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Silvestro Micera

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Publications associées (314)

Shared human–robot proportional control of a dexterous myoelectric prosthesis

Aude Billard, Edoardo D'Anna, Nicolas Sommer, Silvestro Micera, Emanuele Formento, Saurav Aryan, Vincent Alexandre Mendez, Francesco Maria Petrini, Fiorenzo Artoni, Katie Zhi Zhuang

Myoelectric prostheses allow users to recover lost functionality by controlling a robotic device with their remaining muscle activity. Such commercial devices can give users a high level of autonomy, but still do not approach the dexterity of the intact hu ...

2019

A closed-loop hand prosthesis with simultaneous intraneural tactile and position feedback

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

Current myoelectric prostheses allow transradial amputees to regain voluntary motor control of their artificial limb by exploiting residual muscle function in the forearm. However, the overreliance on visual cues resulting from a lack of sensory feedback i ...

AMER ASSOC ADVANCEMENT SCIENCE2019

High frequency shift in Carotid Sinus Nerve and Sympathetic Nerve activity in Type 2 Diabetic Rat Model

Silvestro Micera

Overactivity of the sympathetic nervous system (SNS) is associated to several cardiovascular and metabolic dysfunctions, such as hypertension and insulin resistance. Indirect biochemical measurements and surgical manipulations have provided preliminary evi ...

IEEE2019

Implantable Neural Interfaces and Wearable Tactile Systems for Bidirectional Neuroprosthetics Systems

Silvestro Micera

Neuroprosthetics and neuromodulation represent a promising field for several related applications in the central and peripheral nervous system, such as the treatment of neurological disorders, the control of external robotic devices, and the restoration of ...

WILEY2019

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

Silvestro Micera, Stanisa Raspopovic, Marco Capogrosso, Francesco Maria Petrini, Jacopo Rigosa, Alessandra Pampaloni, Beatrice Barra

Background:The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the process-ing of descending efferent neural signals recorded using peripheral neural interfaces ...

2019

Neurotechnology-aided interventions for upper limb motor rehabilitation in severe chronic stroke

José del Rocio Millán Ruiz, Silvestro Micera, Martina Coscia, John Donoghue, Friedhelm Christoph Hummel, Maximilian Jonas Wessel

Upper limb motor deficits in severe stroke survivors often remain unresolved over extended time periods. Novel neurotechnologies have the potential to significantly support upper limb motor restoration in severely impaired stroke individuals. Here, we revi ...

2019

Combined rehabilitation promotes recovery of motor functionality in a mouse model of stroke

Silvestro Micera, Maria Pasquini

Neuro-rehabilitative research is developing novel strategies to enhance the effectiveness of therapies after stroke by using a combination of physical and plasticizing treatments 1-3. Previous studies have shown that repeated optogenetics stimulation of ne ...

SPIE-INT SOC OPTICAL ENGINEERING2019

Ambulatory Assessment of the Dynamic Margin of Stability Using an Inertial Sensor Network

Silvestro Micera

Loss of stability is a precursor to falling and therefore represents a leading cause of injury, especially in fragile people. Thus, dynamic stability during activities of daily living (ADLs) needs to be considered to assess balance control and fall risk. T ...

2019

Detection of movement onset using EMG signals for upper-limb exoskeletons in reaching tasks

Silvestro Micera

BackgroundTo assist people with disabilities, exoskeletons must be provided with human-robot interfaces and smart algorithms capable to identify the user's movement intentions. Surface electromyographic (sEMG) signals could be suitable for this purpose, bu ...

BioMed Central2019

Combined Rehabilitation Promotes the Recovery of Structural and Functional Features of Healthy Neuronal Networks after Stroke

Silvestro Micera, Francesco Saverio Pavone, Stefano Lai

Rehabilitation is considered the most effective treatment for promoting the recovery of motor deficits after stroke. One of the most challenging experimental goals is to unambiguously link brain rewiring to motor improvement prompted by rehabilitative ther ...

2019

Electrical spinal cord stimulation must preserve proprioception to enable locomotion in humans with spinal cord injury

Camille Georgette Marie Le Goff-Mignardot, Silvestro Micera, Grégoire Courtine, Emanuele Formento, Marco Capogrosso, Jean-Baptiste Mignardot, Fabien Bertrand Paul Wagner, Andreas Rowald, Karen Minassian, Jocelyne Bloch

Epidural electrical stimulation (EES) of the spinal cord restores locomotion in animal models of spinal cord injury but is less effective in humans. Here we hypothesized that this interspecies discrepancy is due to interference between EES and propriocepti ...

2018

Brain-controlled modulation of spinal circuits improves recovery from spinal cord injury

Silvestro Micera, Grégoire Courtine, Marco Bonizzato, Natalia Pavlova, Galyna Pidpruzhnykova, Polina Shkorbatova

The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment recovery from neurological disorders. To test this hypothesis, we conceived a brain-controlled neuromodulation therapy that combines the technical and practi ...

Nature Publishing Group2018

Peptide-based coatings for flexible implantable neural interfaces

Silvestro Micera

In the last decade, the use of flexible biosensors for neuroprosthetic and translational applications has widely increased. Among them, the polyimide (PI)-based thin-film electrodes got a large popularity. However, the usability of these devices is still h ...

Nature Research2018

A neurostimulation system for central nervous stimulation (cns) and peripheral nervous stimulation (pns)

Sophie Marie Marthe Wurth, Silvestro Micera, Grégoire Courtine

The present disclosure relates to a neuromodulation and/or neurostimulation system comprising at least the following components: at least one sensing unit, at least control unit, at least one stimulation unit, at least one Central Nervous System (CNS) stim ...

2018

How are Muscle Synergies Affected by Electromyography Pre-Processing?

Elvira Pirondini, Silvestro Micera, Martina Coscia, Fiorenzo Artoni

2018

Closed-loop control of trunk posture improves locomotion through the regulation of leg proprioceptive feedback after spinal cord injury

Jenifer Cléa Miehlbradt, Sophie Marie Marthe Wurth, Silvestro Micera, Grégoire Courtine, Joachim von Zitzewitz, Eduardo Martin Moraud, Emanuele Formento, Marco Capogrosso

Nature Research2018

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Silvestro Micera

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Shared human–robot proportional control of a dexterous myoelectric prosthesis

A closed-loop hand prosthesis with simultaneous intraneural tactile and position feedback

High frequency shift in Carotid Sinus Nerve and Sympathetic Nerve activity in Type 2 Diabetic Rat Model

Implantable Neural Interfaces and Wearable Tactile Systems for Bidirectional Neuroprosthetics Systems

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

Neurotechnology-aided interventions for upper limb motor rehabilitation in severe chronic stroke

Combined rehabilitation promotes recovery of motor functionality in a mouse model of stroke

Ambulatory Assessment of the Dynamic Margin of Stability Using an Inertial Sensor Network

Detection of movement onset using EMG signals for upper-limb exoskeletons in reaching tasks

Combined Rehabilitation Promotes the Recovery of Structural and Functional Features of Healthy Neuronal Networks after Stroke

Electrical spinal cord stimulation must preserve proprioception to enable locomotion in humans with spinal cord injury

Brain-controlled modulation of spinal circuits improves recovery from spinal cord injury

Peptide-based coatings for flexible implantable neural interfaces

A neurostimulation system for central nervous stimulation (cns) and peripheral nervous stimulation (pns)

How are Muscle Synergies Affected by Electromyography Pre-Processing?

Closed-loop control of trunk posture improves locomotion through the regulation of leg proprioceptive feedback after spinal cord injury

A Wearable Multi-Site System for NMES-Based Hand Function Restoration

Bilateral Tactile Input Patterns Decoded at Comparable Levels But Different Time Scales in Neocortical Neurons

Biomimetic Architectures for Peripheral Nerve Repair: A Review of Biofabrication Strategies

Effective Synchronization of EEG and EMG for Mobile Brain/Body Imaging in Clinical Settings