A method for determining the functional topography of a peripheral nerve ( 10 ) of a user comprising the steps of prearranging an electrode ( 100 ) comprising a number n of channels c i , with i = 1,2..., n, arranging the electrode (100) in such a way that each channel is in contact with the peripheral nerve (10) at a respective contact point p i , with i = 1,2..., n, generating a model of a cross section S of the peripheral nerve ( 10 ) where the area A of the cross section S comprises a number m of areas α j , with j = 1,2,..., m, computing a lead field matrix L = [R j,i ], wherein R j,i is a value that describes the electrostatic relationship between an area α j and a contact point p i of the cross section S, periodic acquisition, by the electrode (100), of a number n of voltage values V ki at instants t k , with k = 1,2,...,S, obtaining a voltage matrix V = [V k,i ], with i = 1,2,...,n, where V ki is the voltage value determined by the channel c i at the contact point p i at the instant t k , periodic acquisition, by at least one medical device, of a number r of values of physiological signals P k,h of the user at instants t k , with k = 1,2,..., s, obtaining a matrix of the physiological signals P = [P k,h ], with h. = 1,2,...,r, where P k k is the value of the h-th physiological signal determined at the instant t k , computing a discrimination matrix = D = [d h,i ], D being function of the matrices V = [V k,i ] and P = [P k,h ], where d h,i is the discrimination coefficient which represents the correlation between the h-th physiological signal P k,h and the i-th voltage value V k,i referred to a same instant t k , computing a spatial filtering matrix Φ DBF = [φ h,j ], φ h,j being the localization index which represents the correlation between the h-th physiological signal and the area α j of said cross section S, generating a functional topography of said peripheral nerve (10), for each h-th physiological signal, wherein each area α j is graphically identified as a function of the corresponding value φ h,j associated with it by the spatial filtering matrix Φ DBF .
