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Alessandro Daducci

Cette personne n’est plus à l’EPFL

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Publications associées (82)

Reducing false positives in tractography with microstructural and anatomical priors

Jean-Philippe Thiran, Alessandro Daducci, Muhamed Barakovic, Gabriel Girard, Maxime Descoteaux

Tractography has proven particularly effective for studying noninvasively the neuronal architecture of the brain but recent studies have showed that the high incidence of false positives can significantly bias any connectivity analysis. We present a novel ...

2018

Non-parametric axon diameter distribution mapping with PGSE: reconstruction of uni- and multimodal distributions

Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Jonathan Rafael Patino Lopez, Tim Bjørn Dyrby

2018

Fast and robust estimation of NODDI parameters using non-Gaussian noise models and spatial regularization

Jean-Philippe Thiran, Alessandro Daducci, Erick Jorge Canales Rodriguez

In this study, we developed a robust inversion algorithm to estimate the Neurite Orientation Dispersion and Density Imaging (NODDI) model. It is based on the Accelerated Microstructure Imaging via Convex Optimization (AMICO) framework. However, in contrast ...

2018

Unified multi-modal characterization of microstructural parameters of brain tissue using diffusion MRI and multi-echo T2 data

Jean-Philippe Thiran, Nicolas Kunz, Alessandro Daducci, Erick Jorge Canales Rodriguez, Marco Pizzolato

In this study, a unified framework to estimate different microstructure indices from diffusion MRI and multi-echo T2 (MET2) data was proposed.The new methodology takes into account the common and complementary information provided by both modalities. While ...

2018

Central nervous system microbleeds in the acute phase are associated with structural integrity by DTI one year after mild traumatic brain injury: A longitudinal study

Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci, Pietro Bontempi

Introduction: Several imaging modalities are under investigation to unravel the pathophysiological mystery of delayed performance deficits in patients after mild traumatic brain injury (mTBI). Although both imaging and neuropsychological studies have been ...

ELSEVIER URBAN & PARTNER SP Z O O2018

Realistic 3D Fiber Crossing Phantom Models for Monte Carlo Diffusion Simulations

Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Gabriel Girard, Gaëtan Olivier D Rensonnet, Jonathan Rafael Patino Lopez

2018

In-vivo Bundle-Specific Axon Diameter Distributions Estimation across the Corpus Callosum

Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Gabriel Girard, Maxime Descoteaux

Over the last decade microstructure imaging has become commonly endorsed to estimate quantitative features of neuronal tissue. However, those techniques estimate the microstructure only locally. Microstructure informed tractography was recently proposed to ...

2017

When does a volume of a bundle achieve saturation? A microstructure informed tractography study

Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Gabriel Girard, Maxime Descoteaux

Volumetric analysis of bundles derived from tractography is a popular statistical measure used in neurological disorder studies. Recent research performed by Gauvin shows that different bundles saturate with different tractography parameters, however, to a ...

2017

Transient networks of spatio-temporal connectivity map communication pathways in brain functional systems

Jean-Philippe Thiran, Pierre Vandergheynst, Xavier Bresson, Patric Hagmann, Alessandra Griffa, Alessandro Daducci, Kirell Maël Benzi, Benjamin Ricaud

The study of brain dynamics enables us to characterize the time-varying functional connectivity among distinct neural groups. However, current methods suffer from the absence of structural connectivity information. We propose to integrate infra-slow neural ...

Elsevier2017

Orientation invariant and non-parametric Axon Diameter Distribution mapping using PGSE and regularized discrete linear modeling

Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci, Anna Auria Rasclosa, Muhamed Barakovic, Tim Bjørn Dyrby

Axon Diameter Distributions (ADDs) change during brain development and are altered in several brain pathologies. Mapping ADDs non-invasively using dMRI could provide a useful biomarker, but existing methods are either parametric, orientation dependent, sur ...

2017

Diagnostic approaches to predict persistent post-traumatic symptoms after mild traumatic brain injury - a literature review

Jean-Philippe Thiran, Alessandro Daducci

Mild traumatic brain injury (mTBI) is one of the most frequently diagnosed neurological disorders in emergency departments. Although there are established recommendations for the diagnosis and treatment in the acute stage, there is an on-going debate in wh ...

Taylor & Francis Ltd2016

Microstructure informed tractography: pitfalls and open challenges

Jean-Philippe Thiran, Alessandro Daducci, Maxime Descoteaux

One of the major limitations of diffusion MRI tractography is that the fiber tracts recovered by existing algorithms are not truly quantitative. Local techniques for estimating more quantitative features of the tissue microstructure exist, but their combin ...

Frontiers Research Foundation2016

Reducing acquisition time for axon diameter mapping using global optimization in the spatial-angular-microstructure space

Jean-Philippe Thiran, Yves Wiaux, David Paul Roger Romascano, Alessandro Daducci, Anna Auria Rasclosa, Erick Jorge Canales Rodriguez, Tim Bjørn Dyrby

State-of-the-art microstructure imaging methods usually fit biophysical models to the diffusion MRI data on a voxel-by-voxel basis using non-linear procedures that require both long acquisitions and processing time. We recently introduced AMICO, a framewor ...

2016

Reducing acquisition time for microstructure imaging with spatially-regularized global optimization

Jean-Philippe Thiran, Yves Wiaux, David Paul Roger Romascano, Alessandro Daducci, Anna Auria Rasclosa, Erick Jorge Canales Rodriguez, Tim Bjørn Dyrby

Microstructure imaging with diffusion MRI (dMRI) is usually based on fitting models to the data using voxelwise nonlinear procedures that (i) are time consuming and (ii) need long acquisitions. Recently, we introduced the AMICO framework to accelerate the ...

2016

Non-invasive quantification of prostate cancer using AMICO framework for VERDICT MR

Alessandro Daducci

2016

A Multi-Contrast MRI Study of Microstructural Brain Damage in Patients with Mild Cognitive Impairment

Meritxell Bach Cuadra, Reto Meuli, Guillaume Bonnier, Daniel Andreas Schmitter, Cristina Granziera, Alessandro Daducci, Alexis Roche

Objectives: The aim of this study was to investigate pathological mechanisms underlying brain tissue alterations in mild cognitive impairment (MCI) using multi-contrast 3 T magnetic resonance imaging (MRI). Methods: Forty-two MCI patients and 77 healthy co ...

Elsevier2015

An evaluation of volume-based morphometry for prediction of mild cognitive impairment and Alzheimer's disease

Meritxell Bach Cuadra, Reto Meuli, Bénédicte Marie Maréchal, Delphine Ribes Lemay, Daniel Andreas Schmitter, Gunnar Krüger, Ahmed Abdulkadir, Cristina Granziera, Alessandro Daducci, Alexis Roche

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer’s disease (AD) related brain atrophy and to enable fairly accurate automated classification of AD patients, mild cognitive impaired patients (MCI) and e ...

Elsevier2015

On evaluating the accuracy and biological plausibility of diffusion MRI tractograms

Jean-Philippe Thiran, David Paul Roger Romascano, Alessandro Daducci

One of the major limitations of diffusion MRI tractography is that the tractograms, i.e. set of fiber tracts, recovered by existing algorithms are not truly quantitative. Hence, the structural connectivity between different brain regions, a.k.a. connectomi ...

2015

Accelerated Microstructure Imaging via Convex Optimization (AMICO) in crossing fibers

Jean-Philippe Thiran, Yves Wiaux, Alessandro Daducci, Anna Auria Rasclosa, Erick Jorge Canales Rodriguez, Tim Bjørn Dyrby

Mapping the local microstructure properties of the tissue in the brain is crucial to understand any pathological condition from a biological perspective. In recent years, microstructure-imaging techniques aimed at extracting such precious information by us ...

2015

Multicontrast connectometry: A new tool to assess cerebellum alterations in early relapsing‐remitting multiple sclerosis

Jonas Richiardi, Gloria Menegaz, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Dimitri Nestor Alice Van De Ville, Guillaume Bonnier, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche, Ying-Chia Lin

Background: Cerebellar pathology occurs in late multiple sclerosis (MS) but little is known about cerebellar changes during early disease stages. In this study, we propose a new multicontrast “connectometry” approach to assess the structural and functional ...

Wiley-Blackwell2015

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