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Alessandro Daducci

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Related publications (82)

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A Novel Spatial-Angular Domain Regularisation Approach for Restoration of Diffusion MRI

Jean-Philippe Thiran, Meritxell Bach Cuadra, Alessandro Daducci

In this paper we tackle the problem of regularisation for inverse problems in single shell diffusion weighted image restoration. Our aim is to recover a high-resolution and denoised DWI signal, prior to any model fitting. The main contribution of our metho ...

SPRINGER-VERLAG BERLIN2019

Diagnostic approaches to predict persistent post-traumatic symptoms after mild traumatic brain injury - a literature review

Jean-Philippe Thiran, Alessandro Daducci

Mild traumatic brain injury (mTBI) is one of the most frequently diagnosed neurological disorders in emergency departments. Although there are established recommendations for the diagnosis and treatment in the acute stage, there is an on-going debate in wh ...

Taylor & Francis Ltd2016

Quantitative Analysis of Myelin and Axonal Remodeling in the Uninjured Motor Network After Stroke

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Cristina Granziera, Gunnar Krüger, Djalel Eddine Meskaldji, Gloria Menegaz

Objectives: Contralesional brain connectivity plasticity was previously reported after stroke. This study aims at disentangling the biological mechanisms underlying connectivity plasticity in the uninjured motor network after an ischemic lesion. In particu ...

2015

A Multi-Contrast MRI Study of Microstructural Brain Damage in Patients with Mild Cognitive Impairment

Meritxell Bach Cuadra, Reto Meuli, Alessandro Daducci, Cristina Granziera, Daniel Andreas Schmitter, Alexis Roche, Guillaume Bonnier

Objectives: The aim of this study was to investigate pathological mechanisms underlying brain tissue alterations in mild cognitive impairment (MCI) using multi-contrast 3 T magnetic resonance imaging (MRI). Methods: Forty-two MCI patients and 77 healthy co ...

Elsevier2015

Migraineurs without aura show microstructural abnormalities in the cerebellum and frontal lobe

Alessandro Daducci, Gunnar Krüger, Cristina Granziera, Nouchine Hadjikhani, David Paul Roger Romascano, Alexis Roche

The involvement of the cerebellum in migraine pathophysiology is not well understood. We used a biparametric approach at high-field MRI (3 T) to assess the structural integrity of the cerebellum in 15 migraineurs with aura (MWA), 23 migraineurs without aur ...

Springer US2013

Comparison of non-parametric T2 relaxometry methods for myelin water quantification

Jean-Philippe Thiran, Tobias Kober, Alessandro Daducci, Tom Hilbert, Erick Jorge Canales Rodriguez, Nicolas Kunz, Marco Pizzolato, Gian Franco Piredda, Thomas Yu

Multi-component T2 relaxometry allows probing tissue microstructure by assessing compartment-specific T2 relaxation times and water fractions, including the myelin water fraction. Non-negative least squares (NNLS) with zero-order Tikhonov regularization is ...

2021

Cerebellar Connectomics Provide New Biomarkers in Early Multiple Sclerosis

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Alessandro Daducci, Cristina Granziera, Gunnar Krüger, Djalel Eddine Meskaldji, Jonas Richiardi, Gloria Menegaz, David Paul Roger Romascano, Alexis Roche, Guillaume Bonnier, Ying-Chia Lin

The cerebellum is involved in multiple sclerosis (MS), but its implication in early phases is still poorly understood. We investigated structural and functional cerebellar connectivity alterations in early and minimally impaired MS patients, and their corr ...

2014

Advances in computational and statistical diffusion MRI

Alessandro Daducci

Computational methods are crucial for the analysis of diffusion magnetic resonance imaging (MRI) of the brain. Computational diffusion MRI can provide rich information at many size scales, including local microstructure measures such as diffusion anisotrop ...

2019

A convex optimization framework for global tractography

Jean-Philippe Thiran, Alessandro Daducci, Alia Lemkaddem

In this article we present a novel approach for diffusion MRI global tractography. Our formulation models the signal in each voxel as a linear combination of fiber-tract basis func- tions, which consist of a comprehensive set of plausible fiber tracts that ...

2013

Sparse wars: A survey and comparative study of spherical deconvolution algorithms for diffusion MRI

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Gabriel Girard, David Paul Roger Romascano, Jonathan Rafael Patino Lopez, Alessandro Daducci, Muhamed Barakovic, Marco Pizzolato, Gaëtan Olivier D Rensonnet

Spherical deconvolution methods are widely used to estimate the brain's white-matter fiber orientations from diffusion MRI data. In this study, eight spherical deconvolution algorithms were implemented and evaluated. These included two model selection tech ...

2019

Microstructure informed tractography: pitfalls and open challenges

Jean-Philippe Thiran, Alessandro Daducci, Maxime Descoteaux

One of the major limitations of diffusion MRI tractography is that the fiber tracts recovered by existing algorithms are not truly quantitative. Local techniques for estimating more quantitative features of the tissue microstructure exist, but their combin ...

Frontiers Research Foundation2016

Hierarchical Microstructure Informed Tractography

Alessandro Daducci, Gabriel Girard, Maxime Descoteaux

Background: Tractography uses diffusion magnetic resonance imaging to noninvasively infer the macroscopic pathways of white matter fibers and it is the only available technique to probe in vivo the structural connectivity of the brain. However, despite thi ...

MARY ANN LIEBERT, INC2021

Orientation invariant and non-parametric Axon Diameter Distribution mapping using PGSE and regularized discrete linear modeling

Jean-Philippe Thiran, Alessandro Daducci, David Paul Roger Romascano, Muhamed Barakovic, Anna Auria Rasclosa

Axon Diameter Distributions (ADDs) change during brain development and are altered in several brain pathologies. Mapping ADDs non-invasively using dMRI could provide a useful biomarker, but existing methods are either parametric, orientation dependent, sur ...

2017

Volume-based vs. voxel-based brain morphometry in Alzheimer's disease prediction

Meritxell Bach Cuadra, Alessandro Daducci, Reto Meuli, Gunnar Krüger, Bénédicte Marie Maréchal, Cristina Granziera, Alexis Roche, Delphine Ribes Lemay, Daniel Andreas Schmitter

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer's disease (AD) related brain atrophy and to enable accurate automated classification of AD patients, mild cognitive impaired (MCI) patients and elderly ...

Proceedings of 23rd International Society for Magnetic Resonance in Medicine (ISMRM) Conference2014

Diffusion Spectrum Imaging after stroke shows structural changes in the contra-lateral motor network correlating with functional recovery

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Cristina Granziera, Gunnar Krüger, Leila Cammoun, Djalel Eddine Meskaldji, Xavier Gigandet, Leila Faiza Ben Hamida Cammoun

There is growing interest in understanding the role of the non-injured contra-lateral hemisphere in stroke recovery. In the experimental field, histological evidence has been reported that structural changes occur in the contra-lateral connectivity and cir ...

2011

Tractography passes the test: Results from the diffusion-simulated connectivity (disco) challenge

Jean-Philippe Thiran, Alessandro Daducci, Erick Jorge Canales Rodriguez, Gabriel Girard, Marco Pizzolato, Ying-Chia Lin, Juan Luis Villarreal Haro

Estimating structural connectivity from diffusion-weighted magnetic resonance imaging is a challenging task, partly due to the presence of false-positive connections and the misestimation of connection weights. Building on previous efforts, the MICCAI-CDMR ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2023

Quantitative comparison of reconstruction methods for intra-voxel fiber recovery from diffusion MRI

Jean-Philippe Thiran, Alessandro Daducci, Yves Wiaux, Erick Jorge Canales Rodriguez, Gloria Menegaz, Maxime Descoteaux, Mathews Jacob, Ying-Chia Lin

Validation is arguably the bottleneck in the diffusion MRI community. This paper evaluates and compares 20 algorithms for recovering the local intra-voxel fiber structure from diffusion MRI data and is based on the results of the "HARDI reconstruction chal ...

Institute of Electrical and Electronics Engineers2014

Assessing feasibility and reproducibility of a bundle-specific framework on in vivo axon diameter estimates at 300mT/m

Jean-Philippe Thiran, Alessandro Daducci, Gabriel Girard, David Paul Roger Romascano, Maxime Descoteaux, Muhamed Barakovic, Jonathan Rafael Patino Lopez, Giorgio Innocenti

In vivo quantitative estimation of axon diameter in the white matter could bring new tools to study the structural and functional architecture of the brain. Recently, the feasibility of axon diameter estimation with diffusion-weighted MRI (DW-MRI) has been ...

2018

3D Residual Eddy Current Field Characterisation: applied to Diffusion Weighted Magnetic Resonance Imaging

Rolf Gruetter, Alessandro Daducci, Gunnar Krüger, François Lazeyras, Kieran O'Brien

Clinical use of the Stejskal-Tanner diffusion weighted images is hampered by the geometric distortions that result from the large residual 3D eddy current field induced. In this work we aimed to predict, using linear response theory, the residual 3D eddy c ...

Institute of Electrical and Electronics Engineers2013

The Connectome Mapper: an open-source processing pipeline to map connectomes with MRI

Jean-Philippe Thiran, Patric Hagmann, Alessandro Daducci, Alessandra Griffa, Reto Meuli, Leila Cammoun, Leila Faiza Ben Hamida Cammoun, Alia Lemkaddem, Xavier Gigandet

Researchers working in the field of global connectivity analysis using diffusion magnetic resonance imaging (MRI) can count on a wide selection of software packages for processing their data, with methods ranging from the reconstruction of the local intra- ...

Public Library of Science2012