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Alessandro Daducci

Cette personne a quitté l’EPFL

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Publications associées (82)

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Unified multi-modal characterization of microstructural parameters of brain tissue using diffusion MRI and multi-echo T2 data

Jean-Philippe Thiran, Alessandro Daducci, Erick Jorge Canales Rodriguez, Nicolas Kunz, Marco Pizzolato

In this study, a unified framework to estimate different microstructure indices from diffusion MRI and multi-echo T2 (MET2) data was proposed.The new methodology takes into account the common and complementary information provided by both modalities. While ...

2018

A new method for accurate in vivo mapping of human brain connections using microstructural and anatomical information

Jean-Philippe Thiran, Alessandro Daducci, Maxime Descoteaux, Muhamed Barakovic

Diffusion magnetic resonance imaging is a noninvasive imaging modality that has been extensively used in the literature to study the neuronal architecture of the brain in a wide range of neurological conditions using tractography. However, recent studies h ...

AMER ASSOC ADVANCEMENT SCIENCE2020

Multimodal microstructure imaging: joint T2-relaxometry and diffusometry to estimate myelin, intracellular, extracellular, and cerebrospinal fluid properties

Jean-Philippe Thiran, Alessandro Daducci, Erick Jorge Canales Rodriguez, Marco Pizzolato

We propose a multimodal joint estimation that aims at exploiting the complementary information of diffusion and multi-echo spin echo data to disentangle the contributions and properties of the main tissue microstructure compartments. We recovered T2, diffu ...

ISMRM2018

A new early and automated MRI-based predictor of motor improvement after stroke

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Gunnar Krüger, Djalel Eddine Meskaldji, Cristina Granziera, Nouchine Hadjikhani, Alexis Roche, Richard Frackowiak

Objectives: In this study, we investigated the structural plasticity of the contralesional motor network in ischemic stroke patients using diffusion magnetic resonance imaging (MRI) and explored a model that combines a MRI-based metric of contralesional ne ...

2012

On evaluating the accuracy and biological plausibility of diffusion MRI tractograms

Jean-Philippe Thiran, Alessandro Daducci, David Paul Roger Romascano

One of the major limitations of diffusion MRI tractography is that the tractograms, i.e. set of fiber tracts, recovered by existing algorithms are not truly quantitative. Hence, the structural connectivity between different brain regions, a.k.a. connectomi ...

2015

Tractostorm: The what, why, and how of tractography dissection reproducibility

Alessandro Daducci, Gabriel Girard, David Paul Roger Romascano, Maxime Descoteaux, Muhamed Barakovic

Investigative studies of white matter (WM) brain structures using diffusion MRI (dMRI) tractography frequently require manual WM bundle segmentation, often called "virtual dissection." Human errors and personal decisions make these manual segmentations har ...

Wiley2020

An evaluation of volume-based morphometry for prediction of mild cognitive impairment and Alzheimer's disease

Reto Meuli, Meritxell Bach Cuadra, Alessandro Daducci, Gunnar Krüger, Cristina Granziera, Bénédicte Marie Maréchal, Daniel Andreas Schmitter, Alexis Roche, Delphine Ribes Lemay

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer’s disease (AD) related brain atrophy and to enable fairly accurate automated classification of AD patients, mild cognitive impaired patients (MCI) and e ...

Elsevier2015

A multi-center study: Intra-scan and inter-scan variability of Diffusion Spectrum Imaging

Jean-Philippe Thiran, Alessandro Daducci, Gunnar Krüger, Alia Lemkaddem, François Lazeyras, Kieran O'Brien

The objective of this study was to investigate whether it is possible to pool together diffusion spectrum imaging data from four different scanners, located at three different sites. Two of the scanners had identical configuration whereas two did not. To m ...

Elsevier2012

3D Printing of Rat Salivary Glands: The Submandibular-Sublingual Complex

Alessandro Daducci

The morphology and the functionality of the murid glandular complex, composed of the submandibular and sublingual salivary glands (SSC), were the object of several studies conducted mainly using magnetic resonance imaging (MRI). Using a 4.7 T scanner and a ...

Wiley-Blackwell2014

Fast and high-resolution myelin water imaging: Accelerating multi-echo GRASE with CAIPIRINHA

Jean-Philippe Thiran, Reto Meuli, Tobias Kober, Alessandro Daducci, Tom Hilbert, Erick Jorge Canales Rodriguez, Marco Pizzolato, Gian Franco Piredda

Purpose Although several MRI methods have been explored to achievein vivomyelin quantification, imaging the whole brain in clinically acceptable times and sufficiently high resolution remains challenging. To address this problem, this work investigates the ...

Wiley2021

Reducing acquisition time for microstructure imaging with spatially-regularized global optimization

Jean-Philippe Thiran, Alessandro Daducci, Yves Wiaux, Erick Jorge Canales Rodriguez, David Paul Roger Romascano, Anna Auria Rasclosa

Microstructure imaging with diffusion MRI (dMRI) is usually based on fitting models to the data using voxelwise nonlinear procedures that (i) are time consuming and (ii) need long acquisitions. Recently, we introduced the AMICO framework to accelerate the ...

2016

Towards a diffusion image processing validation and accuracy prediction framework

Jean-Philippe Thiran, Meritxell Bach Cuadra, Alessandro Daducci, Cristina Granziera, Gloria Menegaz, Alia Lemkaddem

Validation is the main bottleneck preventing the adoption of many medical image processing algorithms in the clinical practice. In the classical approach, a-posteriori analysis is performed based on some objective metrics. In this work, a different approac ...

2011

Reducing acquisition time for axon diameter mapping using global optimization in the spatial-angular-microstructure space

Jean-Philippe Thiran, Alessandro Daducci, Yves Wiaux, Erick Jorge Canales Rodriguez, David Paul Roger Romascano, Anna Auria Rasclosa

State-of-the-art microstructure imaging methods usually fit biophysical models to the diffusion MRI data on a voxel-by-voxel basis using non-linear procedures that require both long acquisitions and processing time. We recently introduced AMICO, a framewor ...

2016

Microstructural alterations in the brain of well treated HIV+ patients with minor neurocognitive disorders: a multi-contrast MRI study at 3T

Alessandro Daducci, Cristina Granziera, Gunnar Krüger, Djalel Eddine Meskaldji, Alexis Roche

2012

When does a volume of a bundle achieve saturation? A microstructure informed tractography study

Jean-Philippe Thiran, Alessandro Daducci, Gabriel Girard, David Paul Roger Romascano, Muhamed Barakovic, Maxime Descoteaux

Volumetric analysis of bundles derived from tractography is a popular statistical measure used in neurological disorder studies. Recent research performed by Gauvin shows that different bundles saturate with different tractography parameters, however, to a ...

2017

Reducing false positives in tractography with microstructural and anatomical priors

Jean-Philippe Thiran, Alessandro Daducci, Gabriel Girard, Maxime Descoteaux, Muhamed Barakovic

Tractography has proven particularly effective for studying noninvasively the neuronal architecture of the brain but recent studies have showed that the high incidence of false positives can significantly bias any connectivity analysis. We present a novel ...

2018

l0-deconvolution for compressive diffusion MRI

Jean-Philippe Thiran, Alessandro Daducci, Yves Wiaux, Anna Auria Rasclosa

Diffusion MRI is a well established imaging modality providing a powerful way to non-invasively probe the structure of the white matter. Despite the potential of the technique, the intrinsic long scan times of these sequences have hampered their use in cli ...

2013

On the reproducibility and anatomical correspondence of DSI tractography

Jean-Philippe Thiran, Reto Meuli, Patric Hagmann, Alessandro Daducci, Gunnar Krüger, Leila Cammoun, Cristina Granziera, Xavier Gigandet, Leila Faiza Ben Hamida Cammoun

Diffusion spectrum imaging (DSI) is increasingly explored in clinical research. The quantitative value of the DSI technique, however, has still to be established. In this context, a better understanding of the reproducibility and the anatomical corresponde ...

2010

Anatomical Priors to improve Global Tractography

Jean-Philippe Thiran, Alessandro Daducci, Alia Lemkaddem

The main assumption of fiber-tracking algorithms is that fiber trajectories are represented by paths of highest diffusion, which is usually accomplished by following the principal diffusion directions in every voxel. The state-of-the-art approaches known a ...

2014

Simulation-based evaluation of susceptibility distortion correction methods in diffusion MRI for connectivity analysis

Meritxell Bach Cuadra, Alessandro Daducci, Kieran O'Brien

Connectivity analysis on diffusion MRI data of the whole- brain suffers from distortions caused by the standard echo- planar imaging acquisition strategies. These images show characteristic geometrical deformations and signal destruction that are an import ...

2014