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Publications associées (209)

Nickamine and Analogous Nickel Pincer Catalysts for Cross-Coupling of Alkyl Halides and Hydrosilylation of Alkenes

CONSPECTUS: Ligand development plays an essential role in the advance of homogeneous catalysis. Tridentate, meridionally coordinating ligands, commonly termed pincer ligands, have been established as a privileged class of ligands in catalysis because they ...

American Chemical Society2019

Renewable hydrogen generation from a dual-circuit redox flow battery

Hubert Girault, Christos Comninellis, Xile Hu, Heron Vrubel, Véronique Amstutz, Kathryn Ellen Toghill

Redox flow batteries (RFBs) are particularly well suited for storing the intermittent excess supply of renewable electricity; so-called “junk” electricity. Conventional RFBs are charged and discharged electrochemically, with electricity stored as chemical ...

Royal Soc Chemistry2014

Hydrogen evolution from a copper(I) oxide photocathode coated with an amorphous molybdenum sulphide catalyst

Michael Graetzel, Xile Hu, Heron Vrubel, Stanley David Tilley, Carlos Gilberto Morales Guio

Concerns over climate change resulting from accumulation of anthropogenic carbon dioxide in the atmosphere and the uncertainty in the amount of recoverable fossil fuel reserves are driving forces for the development of renewable, carbon-neutral energy tech ...

Nature Publishing Group2014

Growth and Activation of an Amorphous Molybdenum Sulfide Hydrogen Evolving Catalyst

Xile Hu, Heron Vrubel

Amorphous molybdenum sulfide films, prepared by electrodeposition, are a class of highly active catalysts for hydrogen evolution. The growth mechanism of the films and the true active species were unclear. Herein, we report a study of the growth and activa ...

American Chemical Society2013

Electronic Elements Governing the Binding of Small Molecules to a [Fe]-hydrogenase Mimic

Xile Hu, Matthew Wodrich

[Fe]-hydrogenase, one of three types of hydrogenases, activates molecular hydrogen. Here, using DFT computations, we examine the electronic elements governing the binding of small ligands to a recently synthesized [Fe]-hydrogenase biomimic. Computed reacti ...

Wiley-Blackwell2013

Spectroscopic and Electrokinetic Evidence for a Bifunctional Mechanism of the Oxygen Evolution Reaction**

Xile Hu, Lichen Bai, Seunghwa Lee

A bifunctional oxygen evolution reaction (OER) mechanism, in which the energetically demanding step of the attack of hydroxide on a metal oxo unit is facilitated by a hydrogen atom transfer to a second site, has the potential to circumvent the scaling rela ...

Wiley-VCH Verlag GmbH2021

Synthesis and Reactivity of Mononuclear Iron Models of [Fe]-Hydrogenase that Contain an Acylmethylpyridinol Ligand

Xile Hu, Dafa Chen

[Fe]-hydrogenase has a single iron-containing active site that features an acylmethylpyridinol ligand. This unique ligand environment had yet to be reproduced in synthetic models; however the synthesis and reactivity of a new class of small molecule mimics ...

Wiley-V C H Verlag Gmbh2014

Enantio- and diastereoselective construction of vicinal C(sp(3)) centres via nickel-catalysed hydroalkylation of alkenes

Xile Hu, Srikrishna Bera, Chao Fan

In drug discovery, the proportion of aliphatic carbons (C(sp(3))) and the presence of chiral carbons in organic molecules are positively correlated to their chance of clinical success. Although methods exist for the synthesis of chiral C(sp(3))-rich molecu ...

2022

Cu Photoredox Catalysts Supported by a 4,6-Disubstituted 2,2 '-Bipyridine Ligand: Application in Chlorotrifluoromethylation of Alkenes

Xile Hu, Murat Alkan

Interest in base metal catalysis motivates the development of Cu-based photoredox catalysts for organic synthesis. However, only a few Cu catalysts have been applied in photoredox reactions, the majority of which contain one or two 1,10-phenanthroline liga ...

2018

A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC

Xile Hu, Tao Xu, Lichen Bai

[Fe]-hydrogenase hosts an iron-guanylylpyridinol (FeGP) cofactor. The FeGP cofactor contains a pyridinol ring substituted with GMP, two methyl groups, and an acylmethyl group. HcgC, an enzyme involved in FeGP biosynthesis, catalyzes methyl transfer from S- ...

Wiley-VCH Verlag GmbH2017

High-Efficiency Anion Exchange Membrane Water Electrolysis Employing Non-Noble Metal Catalysts

Xile Hu, Pengzuo Chen

Alkaline anion exchange membrane (AEM) water electrolysis is a promising technology for producing hydrogen using renewable energies. However, current AEM electrolyzers still employ noble-metal-containing electrocatalysts, or have significant overpotential ...

2020

Stability profiles of transition metal oxides in the oxygen evolution reaction in alkaline medium

Xile Hu, Aliki Moysiadou

The electrochemical water splitting reaction can convert renewable electricity into clean hydrogen fuel. The efficiency of water splitting is limited to a large extent by the sluggish oxygen evolution reaction (OER). Numerous transition metal oxides have b ...

Royal Society of Chemistry2019

Smart chemistry for traceless release of anticancer therapeutics

Xile Hu, Li Tang, Céline Jasmin Prange

In the design of delivery strategies for anticancer therapeutics, the controlled release of intact cargo at the destined tumor and metastasis locations is of particular importance. To this end, stimuli-responsive chemical linkers have been extensively inve ...

Elsevier Sci Ltd2023

Encapsulated Co–Ni alloy boosts high-temperature CO2 electroreduction

Jiaming Tian, Xile Hu, Jeremy Luterbacher, Wenhao Ren, Wenchao Ma, Seongmin Jin

Electrochemical CO 2 reduction into chemicals and fuels holds great promise for renewable energy storage and carbon recycling 1–3 . Although high-temperature CO 2 electroreduction in solid oxide electrolysis cells is industrially relevant, current catalyst ...

Springer Science and Business Media LLC2025

Copper lattice tension boosts full-cell CO electrolysis to multi-carbon olefins and oxygenates

Xile Hu, Wenchao Ma

Electrocatalytic upgrading of CO to value-added multi-carbon (C2+) compounds is a promising approach to efficient carbon utilization. However, current full-cell systems have low energy conversion effi-ciencies under practical conditions due to the requirem ...

Cell Press2023

Hydrogen evolution catalyzed by MoS3 and MoS2 particles

Xile Hu, Heron Vrubel, Daniel Andreas Merki

Amorphous MoS3 particles are prepared using a simple chemical method. Several deposition techniques are developed to fabricate electrodes loaded with MoS3 particles. These electrodes are highly active for hydrogen evolution. The catalytically active specie ...

2012

In Vitro Biosynthesis of the [Fe]-Hydrogenase Cofactor Verifies the Proposed Biosynthetic Precursors

Xile Hu, Huijie Pan

In the FeGP cofactor of [Fe]-hydrogenase, low-spin Fe-II is in complex with two CO ligands and a pyridinol derivative; the latter ligates the iron with a 6-acylmethyl substituent and the pyridinol nitrogen. A guanylylpyridinol derivative, 6-carboxymethyl-3 ...

Wiley-VCH Verlag GmbH2022

Deciphering Iron-Dependent Activity in Oxygen Evolution Catalyzed by Nickel-Iron Layered Double Hydroxide

Xile Hu, Lichen Bai, Seunghwa Lee

Nickel iron oxyhydroxide is the benchmark catalyst for the oxygen evolution reaction (OER) in alkaline medium. Whereas the presence of Fe ions is essential to the high activity, the functions of Fe are currently under debate. Using oxygen isotope labeling ...

Wiley-VCH Verlag GmbH2020

Operando Nanoscale Characterization Reveals Fe Doping of Ni Oxide Enhances Oxygen Evolution Reaction via Fragmentation and Formation of Dual Active Sites

Xile Hu, Magalí Alejandra Lingenfelder, Victor Carle Adrien Boureau, Seunghwa Lee, Yunchang Liang, Karla Banjac

Efficient catalytic water splitting demands advanced catalysts to improve the slow kinetics of the oxygen evolution reaction (OER). Earth-abundant transition metal oxides show promising OER activity in alkaline media. However, most experimental information ...

2025

Deoxygenative trifluoromethylthiolation of carboxylic acids

Xile Hu, Runze Mao, Srikrishna Bera, Alexis Baptiste Cheseaux

Here we describe a deoxygenative trifluoromethylthiolation method that yields trifluoromethyl thioesters from readily available carboxylic acids. The method is built upon an "umpolung" strategy where triphenylphosphine is used to first activate an electrop ...

2019