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Ilaria Malanchi

Cette personne a quitté l’EPFL

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Publications associées (7)

Page 1 sur 1

Interactions between cancer stem cells and their niche govern metastatic colonization

Jörg Hülsken, Hans-Anton Lehr, Albert Santamaria Martinez, Ilaria Malanchi

Metastatic growth in distant organs is the major cause of cancer mortality. The development of metastasis is a multistage process with several rate-limiting steps. Although dissemination of tumour cells seems to be an early and frequent event, the successf ...

2012

Cancer stem cells: never Wnt away from the niche

Jörg Hülsken, Ilaria Malanchi

PURPOSE OF REVIEW: The last years of cancer research have established the concept of cancer stem cells (CSCs) as a subpopulation of cells within a tumor entirely responsible for tumorigenesis. This has aroused expectations that targeting cancer stem cells ...

2009

T-cell development occurs in the combined absence of the canonical Wnt signal-transducers beta- and gamma-catenin

Jörg Hülsken, Fabien Kuttler, Ilaria Malanchi

2008

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

Jörg Hülsken, Ilaria Malanchi

Continuous turnover of epithelia is ensured by the extensive self-renewal capacity of tissue-specific stem cells. Similarly, epithelial tumour maintenance relies on cancer stem cells (CSCs), which co-opt stem cell properties. For most tumours, the cellular ...

2008

Putting cancer stem cells in context

Jörg Hülsken, Ilaria Malanchi

Elsevier Sci Ltd2013

Targeting extracellular matrix molecules for the treatment of cancer

Jörg Hülsken, Ilaria Malanchi

The present invention relates to an agent able to block a cancer supportive function of a fasciclin protein family member and to pharmaceutical compositions containing the same. ...

2011

Interactions Between Breast Cancer Stem Cells and their Niche Govern Metastatic Colonization of the Lung

Jörg Hülsken, Ilaria Malanchi

Elsevier Sci Ltd2012