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Alessandra Griffa

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Publications associées (82)

Diffusion spectrum imaging connectomics: a biomarker for staging in psychotic disorders

Jean-Philippe Thiran, Patric Hagmann, Alessandra Griffa, Kim Do

2015

Characterizing the connectome in schizophrenia with diffusion spectrum imaging

Jean-Philippe Thiran, Patric Hagmann, Alessandra Griffa, Kim Do

Schizophrenia is a complex psychiatric disorder characterized by disabling symptoms and cognitive deficit. Recent neuroimaging findings suggest that large parts of the brain are affected by the disease, and that the capacity of functional integration betwe ...

Wiley-Blackwell2015

Intrahemispheric cortico-cortical connections of the human auditory cortex

Jean-Philippe Thiran, Patric Hagmann, Stephanie Clarke, Reto Meuli, Alessandra Griffa, Leila Cammoun

The human auditory cortex comprises the supratemporal plane and large parts of the temporal and parietal convexities. We have investigated the relevant intrahemispheric cortico-cortical connections using in vivo DSI tractography combined with landmark-base ...

Springer Heidelberg2015

Mapping resting-state dynamics on spatio-temporal graphs: a combined functional and diffusion MRI approach

Jean-Philippe Thiran, Pierre Vandergheynst, Xavier Bresson, Patric Hagmann, Alessandra Griffa, Kirell Maël Benzi, Benjamin Ricaud

2015

Resting-brain functional connectivity predicted by analytic measures of network communication

Jean-Philippe Thiran, Patric Hagmann, Alessandra Griffa, Olaf Sporns

6 The complex relationship between structural and functional connectivity, as measured by noninvasive imaging of the human brain, poses many unresolved challenges and open questions. Here, we apply analytic measures of network communication to the structur ...

National Academy of Sciences2014

MR connectomics identifies a distributed subnetwork lesioned in schizophrenia

Jean-Philippe Thiran, Patric Hagmann, Alessandra Griffa, Kim Do

2014

Multi-scale integration and predictability in resting state brain activity

Patric Hagmann, Alessandra Griffa

The human brain displays heterogeneous organization in both structure and function. Here we develop a method to characterize brain regions and networks in terms of information-theoretic measures. We look at how these measures scale when larger spatial regi ...

2014

Glutathione Deficit Affects White Matter Integrity in Prefrontal Cortex and Impairs Brain Connectivity in Schizophrenia

Jean-Philippe Thiran, Patric Hagmann, Rolf Gruetter, Lijing Xin, Alessandra Griffa, Aline Monin, Kim Do

Elsevier Science Inc2014

Comparing connectomes across subjects and populations at different scales

Stephan Morgenthaler, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Patric Hagmann, Alessandra Griffa, Elda Fischi Gomez

Brain connectivity can be represented by a network that enables the comparison of the different patterns of struc- tural and functional connectivity among individuals. In the literature, two levels ofstatistical analysis have been con- sidered in comparing ...

2013

A Connectome-Based Comparison of Diffusion MRI Schemes

Jean-Philippe Thiran, Xavier Gigandet, Patric Hagmann, Reto Meuli, Alessandra Griffa, Gunnar Krüger, Tobias Kober, Alessandro Daducci

Public Library of Science2013

Group-representative partitions of human brain structural networks

Jean-Philippe Thiran, Patric Hagmann, Alessandra Griffa, Kim Do

2013

Structural connectomics in brain diseases

Jean-Philippe Thiran, Patric Hagmann, Philipp Baumann, Alessandra Griffa

Imaging the connectome in vivo has become feasible through the integration of several rapidly developing fields of science and engineering, namely magnetic resonance imaging and in particular diffusion MRI on one side, image processing and network theory o ...

Elsevier2013

Automated analysis of single stem cells in microfluidic traps

Matthias Lütolf, Olivier Burri, Alessandra Griffa, Stefan Kobel, Arne Seitz, Mukul Girotra

We report a reliable strategy to perform automated image cytometry of single (non-adherent) stem cells captured in microfluidic traps. The method rapidly segments images of an entire microfluidic chip based on the detection of horizontal edges of microflui ...

2012

Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy

Nikolaos Stergiopoulos, Michaël Unser, Daniel Sage, Alessandra Griffa, Aristotelis Agianniotis, Jelle Tymen Christiaan Schrauwen

Mechanical properties of the adventitia are largely determined by the organization of collagen fibers. Measurements on the waviness and orientation of collagen, particularly at the zero-stress state, are necessary to relate the structural organization of c ...

Springer Verlag2012

Altered structural connectivity in patients with medial temporal lobe epilepsy: A Diffusion Spectrum Imaging and Graph Analysis study

Jean-Philippe Thiran, Alia Lemkaddem, Alessandra Griffa, Alessandro Daducci

In this study we investigated the effect of medial temporal lobe epilepsy (MTLE) on the global characteristics of brain connectivity estimated by topological measures. We used DSI (Diffusion Spectrum Imaging) to construct a connectivity matrix where the no ...

2012

Whole-brain structural connectivity in temporal lobe epilepsy: a Diffusion Spectrum Imaging study

Jean-Philippe Thiran, François Lazeyras, Alia Lemkaddem, Alessandra Griffa, Alessandro Daducci

Introduction: Medial Temporal Lobe Epilepsy (mTLE) with hippocampal sclerosis is the most frequent cause of drug-resistant focal epilepsy in adults. These patients suffer from widespread subtle white matter abnormalities and abnormal functional connectivit ...

2012

The Connectome Mapper: an open-source processing pipeline to map connectomes with MRI

Jean-Philippe Thiran, Xavier Gigandet, Patric Hagmann, Reto Meuli, Alia Lemkaddem, Alessandra Griffa, Alessandro Daducci, Leila Cammoun

Researchers working in the field of global connectivity analysis using diffusion magnetic resonance imaging (MRI) can count on a wide selection of software packages for processing their data, with methods ranging from the reconstruction of the local intra- ...

Public Library of Science2012

The influence of frontal glutathione levels on white matter connectivity in healthy and early psychosis subjects: a preliminary study

Jean-Philippe Thiran, Patric Hagmann, Rolf Gruetter, Lijing Xin, Alessandra Griffa, Kim Do

2012

Graph theory to analyse developmental plasticity in connectivity of preterm children

Jean-Philippe Thiran, François Lazeyras, Alessandra Griffa, Elda Fischi Gomez, Alessandro Daducci

2012

Comparison of Deconvolution Software in 3D Microscopy: A User Point of View—Part 1

Daniel Sage, Alessandra Griffa

Deconvolution is an image restoration technique which improves image contrast, resolution and signal to noise ratio. In modern optical microscopy and biological research deconvolution is becoming a fundamental processing step which allows for better image ...

EMS2010

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