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Tamar Kohn

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Publications associées (102)

Viral Transfer and Inactivation through Zooplankton Trophic Interactions

Virginie Bachmann, Tamar Kohn, Margot Ninon Lauren Olive, Xavier Fernandez Cassi

Waterborne viruses are responsible for numerous diseases and are abundant in aquatic systems. Understanding the fate of viruses in natural systems has important implications for human health. This research quantifies the uptake of bacteriophage T4 and the ...

2020

Global sensitivity analysis of environmental, water quality, photoreactivity, and engineering design parameters in sunlight inactivation of viruses

Tamar Kohn, Xinyi Zhang

Sunlight-mediated inactivation of microorganisms is a low-cost approach to disinfect drinking water and wastewater. The reactions involved are affected by a wide range of factors, and a lack of knowledge about their relative importance make it challenging ...

2020

Removal of trace organic contaminants from wastewater by superfine powdered activated carbon (SPAC) is neither affected by SPAC dispersal nor coagulation

Florence Bonvin, Loïc Decrey, Tamar Kohn

Powdered activated carbon (PAC) is increasingly used as tertiary treatment for the removal of trace organic contaminants (TrOCs) from wastewater (WW). To enhance the sorption kinetics and capacity, the PAC particles can be milled down to super fine powdere ...

2020

Relationship Between Inactivation and Genome Damage of Human Enteroviruses Upon Treatment by UV254, Free Chlorine, and Ozone

Virginie Bachmann, Tamar Kohn, Jason Robert Torrey, Suzanne Marie Young

Quantitative PCR (qPCR) is a convenient tool for monitoring virus concentrations in water and wastewater treatment trains, though it only informs about virus presence, but not infectivity. This limitation can be overcome if the relationship between infecti ...

2019

Health risks for sanitation service workers along a container-based urine collection system and resource recovery value chain

Tamar Kohn, Simon Schindelholz, Timothy R. Julian

Container-based sanitation (CBS) within a comprehensive service system value chain offers a low-cost sanitation option with potential for revenue generation, but may increase microbial health risks to sanitation service workers. This study assessed occupat ...

2019

Differences in viral disinfection mechanisms as revealed by quantitative transfection of Echovirus 11 genomes

Tamar Kohn, Urs von Gunten, Jason Robert Torrey

Virus inactivation mechanisms can be elucidated by methods which measure the loss of specific virus functionality (e.g., host attachment, genome internalization, genome replication). Genome functionality is frequently assessed by PCR-based methods, which a ...

2019

Transfer of Enteric Viruses Adenovirus and Coxsackievirus and Bacteriophage MS2 from Liquid to Human Skin (vol 84, e01809, 2018)

Tamar Kohn, Timothy R. Julian

AMER SOC MICROBIOLOGY2019

Proxies to monitor the inactivation of viruses by ozone in surface water and wastewater effluent

Tamar Kohn, Camille Wolf, Urs von Gunten, Annalisa Pavese

Ozone treatment is an effective barrier against viral pathogens, therefore it is an integral part of many water and wastewater treatment trains. However, the efficacy of ozone treatment remains difficult to monitor, due to the lack of methods to track viru ...

2019

The utility of flow cytometry for potable reuse

Tamar Kohn, Brian Pecson, Krista Rule Wigginton

Protecting public health from pathogens is critical when treating wastewater to drinking water standards (i.e., planned water reuse). Viruses are a principal concern, yet real-time monitoring strategies do not currently measure virus removal through reuse ...

2019

Variability in Disinfection Resistance between Currently Circulating Enterovirus B Serotypes and Strains

Tamar Kohn, Simon Meister, Marius Klinger, Matthew Eric Verbyla

The susceptibility of waterborne viruses to disinfection is known to vary between viruses and even between closely related strains, yet the extent of this variation is not known. Here, different enteroviruses (six strains of coxsackievirus B5, two strains ...

2018

Kinetics of inactivation of waterborne enteric viruses by ozone

Tamar Kohn, Camille Wolf, Urs von Gunten

Ozone is an effective disinfectant against all types of waterborne pathogens. However, accurate and quantitative kinetic data regarding virus inactivation by ozone is scarce, due to the experimental challenges associated with the high reactivity of ozone t ...

2018

Sunlight-mediated inactivation of health-relevant microorganisms in water: A review of mechanisms and modeling approaches

Tamar Kohn, Krista Rule Wigginton, Yang Liu

Health-relevant microorganisms present in natural surface waters and engineered treatment systems that are exposed to sunlight can be inactivated by a complex set of interacting mechanisms. The net impact of sunlight depends on the solar spectral irradianc ...

2018

Inaktivierung von Viren im Wasser

Tamar Kohn

Durch Wasser übertragene, infektiöse Humanviren sind oft im Rohwasser präsent. Bereits die Ingestion einer kleinen Anzahl solcher Viren kann diverse Krankheiten wie Gastroenteritis und Atemwegserkrankungen oder Hepatitis auslösen. Es ist also wichtig, Vire ...

2018

Transfer of enteric viruses (adenovirus and coxsackievirus) and bacteriophage (MS2) from liquid to human skin

Tamar Kohn, Ana Karina Pitol Garcia, Timothy R. Julian

Indirect exposure to waterborne viruses increases risk of infection, especially amongst children with frequent hand-to-mouth contacts. Here, we quantified the transfer of one bacteriophage (MS2) and two enteric viruses (adenovirus and coxsackievirus) from ...

2018

Experimental adaptation of human echovirus 11 to ultraviolet radiation leads to tolerance to disinfection and resistance to ribavirin

Virginie Bachmann, Tamar Kohn, Hyunjin Shim, Qingxia Zhong, Jeffrey David Jensen, Anna Carratala Ripolles

Ultraviolet light in the UVC range is a commonly used disinfectant to control viruses in clinical settings and water treatment. Here, we employed an experimental evolution approach to investigate the adaptation of human echovirus 11 to disinfection by UVC, ...

2017

Resistance of echovirus 11 to ClO2 is associated with enhanced host receptor use, altered entry routes and high fitness

Virginie Bachmann, Tamar Kohn, Hyunjin Shim, Qingxia Zhong, Jeffrey David Jensen, Anna Carratala Ripolles

Waterborne viruses can exhibit resistance to common water disinfectants, yet the mechanisms that allow them to tolerate disinfection are poorly understood. Here, we generated echovirus 11 (E11) with resistance to chlorine dioxide (ClO2) by experimental evo ...

Amer Chemical Soc2017

Identification of the inactivating factors and mechanisms exerted on MS2 coliphage in concentrated synthetic urine

Loïc Decrey, Tamar Kohn

Volume reduction (condensation) is a key for the practical usage of human urine as a fertilizer because it enables the saving of storage space and the reduction of transportation cost. However, concentrated urine may carry infectious disease risks resultin ...

Elsevier2017

Virus transfer at the skin-liquid interface

Tamar Kohn, Timothy R. Julian

Understanding virus transfer between liquid and skin is necessary to estimate transmission during water-related activities. In the present study, we modeled virus transfer from liquid-to-skin and skin-to-liquid. Specifically, we performed human subject stu ...

Amer Chemical Soc2017

Virus inactivation in stored human urine, sludge and animal manure under typical conditions of storage or mesophilic anaerobic digestion

Loïc Decrey, Tamar Kohn

Viruses represent major disease transmitting agents carried by human excreta and animal manure. Understanding virus inactivation is therefore essential in preventing microbial spread due to inadequate treatment of these materials. Here, we investigated the ...

Royal Soc Chemistry2017

Cross-resistance of UV- or chlorine dioxide-resistant echovirus 11 to other disinfectants

Virginie Bachmann, Tamar Kohn, Qingxia Zhong, Anna Carratala Ripolles, Rachele Ossola

The emergence of waterborne viruses with resistance to disinfection has been demonstrated in the laboratory and in the environment. Yet, the implications of such resistance for virus control remain obscure. In this study we investigate if viruses with resi ...

Frontiers Media SA2017

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