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Rolf Gruetter

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Publications associées (418)

Longitudinal neurochemical modifications in the aging mouse brain measured in vivo by 1H magnetic resonance spectroscopy

Rolf Gruetter, João Miguel das Neves Duarte, Kim Do

Alterations to brain homeostasis during development are reflected in the neurochemical profile determined noninvasively by (1)H magnetic resonance spectroscopy. We determined longitudinal biochemical modifications in the cortex, hippocampus, and striatum o ...

Elsevier Science Inc2014

FID-guided retrospective motion correction based on autofocusing

Rolf Gruetter, Gunnar Krüger, Tobias Kober, Cristina Granziera, Maryna Volodimirivna Waszak

This work investigates the possibility of using FID navigator signals to improve the performance of a recently proposed autofocusing-based retrospective motion correction technique. FID navigators were incorporated into an MP-RAGE sequence and 3 subjects w ...

2014

Genetic Association with Prefrontal Glutathione Deficit: A 3T 1H MRS Study in Early Psychosis

Rolf Gruetter, Lijing Xin, Huanxiang Lu, Kim Do

Elsevier Science Inc2014

Impact of hepatic lipid accumulation and composition on glucose tolerance and insulin sensitivity: a longitudinal study in male and female mice

Rolf Gruetter, Hongxia Lei, Ana Francisca Leal Silva Soares

Background and aims: Metabolic disruptions characterized by high hepatic lipid content (HLC) are associated with impairments in whole body glucose homeostasis. To gain insight on the role of hepatic lipids in the metabolic performance in the absence artifi ...

Springer2014

Protective effects of maternal nutritional supplementation with lactoferrin on growth and brain metabolism

Rolf Gruetter, Yohan Van de Looij, Sylviane Métairon

Background:Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. The impact of maternal supplementati ...

Nature Publishing Group2014

Are glutamate and lactate increases ubiquitous to physiological activation? A 1H functional MR spectroscopy study during motor activation in human brain at 7Tesla

Rolf Gruetter, Benoît Schaller, Lijing Xin

Recent studies at high field (7 Tesla) have reported small metabolite changes, in particular lactate and glutamate (below 0.3 μmol/g) during visual stimulation. These studies have been limited to the visual cortex because of its high energy metabolism and ...

Elsevier2014

MRS glucose mapping and PET joining forces: Re-evaluation of the lumped constant in the rat brain under isoflurane anaesthesia

Rolf Gruetter, João Miguel das Neves Duarte, Hongxia Lei, Malte Alf

Although numerous positron emission tomography (PET) studies with ((8) F-fluoro-deoxyglucose) FDG have reported quantitative results on cerebral glucose kinetics and consumption, there is a large variation between the absolute values found in the literatur ...

Wiley-Blackwell2014

Phase-based manganese enhanced MRI, a new methodology to enhance brain cytoarchitectural contrast and study manganese uptake

Rolf Gruetter, José Pedro Rebelo Ferreira Marques, Rajika Maddage

Purpose As the magnetic susceptibility induced frequency shift increases linearly with magnetic field strength, the present work evaluates manganese as a phase imaging contrast agent and investigates the dose dependence of brain enhancement in comparison t ...

Wiley-Blackwell2014

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

Arnaud Comment, Rolf Gruetter, Josefina Adriana Maria Bastiaansen, Yuhei Takado, Hikari Ananda Infinity Yoshihara

2014

In vivo 13C MRS in the mouse brain at 14.1 T and metabolic flux quantification during infusion of [1,6-13C2] Glucose

Bernard Lanz, Rolf Gruetter, Cristina Ramona Cudalbu, Carola Jaquelina del Carmen Romero, Marta Lai

2014

In vivo quantification of neuro-glial metabolism and glial glutamate concentration using 1H-[13C] MRS at 14.1T

Bernard Lanz, Rolf Gruetter, Lijing Xin

Astrocytes have recently become a major center of interest in neurochemistry with the discoveries on their major role in brain energy metabolism. An interesting way to probe this glial contribution is given by in vivo 13C NMR spectroscopy coupled with the ...

Wiley-Blackwell2014

Neurochemical profile differentiation of glioma induced by cancer stem cells expressing WIF1: a 1H-MRS longitudinal study at 14.1T

Bernard Lanz, Rolf Gruetter, Cristina Ramona Cudalbu, Marta Lai

2014

FID navigator triggered acquisition of imaging navigators for retrospective head motion correction

Reto Meuli, Rolf Gruetter, Gunnar Krüger, Maryna Volodimirivna Waszak, Pavel Falkovskiy

2014

Impact of hepatic lipid accumulation and composition on glucose tolerance and insulin sensitivity: a longitudinal study in male and female mice

Rolf Gruetter, Hongxia Lei, Ana Francisca Leal Silva Soares

Springer2014

Metabolic flux analysis of acetylcarnitine turnover and mitochondrial oxidation of [2-13C]acetate in rat skeletal muscle in vivo measured by 13C MRS

Rolf Gruetter, João Miguel das Neves Duarte, Josefina Adriana Maria Bastiaansen

2014

Glutathione Deficit Affects White Matter Integrity in Prefrontal Cortex and Impairs Brain Connectivity in Schizophrenia

Jean-Philippe Thiran, Patric Hagmann, Rolf Gruetter, Lijing Xin, Alessandra Griffa, Aline Monin, Kim Do

Elsevier Science Inc2014

Human finger somatotopy in areas 3b, 1, and 2: A 7T fMRI study using a natural stimulus

Roberto Martuzzi, Rolf Gruetter, Olaf Blanke, Juliane Farthouat, Wietske Van der Zwaag

To study the properties of human primary somatosensory (S1) cortex as well as its role in cognitive and social processes, it is necessary to noninvasively localize the cortical representations of the body. Being arguably the most relevant body parts for ta ...

Wiley-Blackwell2014

Multi-modal assessment of long-term erythropoietin treatment after neonatal hypoxic-ischemic injury in rat brain

Rolf Gruetter, Yohan Van de Looij

Erythropoietin (EPO) has been recognized as a neuroprotective agent. In animal models of neonatal brain injury, exogenous EPO has been shown to reduce lesion size, improve structure and function. Experimental studies have focused on short course treatment ...

Public Library of Science2014

Studying glioblastoma progression in a rat model of human glioma initiating cells using 1H MRS and DTI

Arnaud Comment, Rolf Gruetter, Cristina Ramona Cudalbu, Mor-Miri Mishkovsky, Emine Can

2014

Ultra-High Field Birdcage Coils: a Comparison Study at 14.1T

Arnaud Comment, Rolf Gruetter, Hongxia Lei, Tian Cheng

An essential feature of magnetic resonance (MR) probes for magnetic resonance imaging and spectroscopy is the ability to generate uniform B-1(+) excitation in a volume of interest. When the magnetic field strength is increased, leading to an increase in re ...

Ieee2014

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