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Rolf Gruetter

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Publications associées (418)

Three-dimensional echo planar imaging with controlled aliasing: A sequence for high temporal resolution functional MRI

Rolf Gruetter, Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques, Mayur Narsude, Daniel Gallichan

Purpose In this work, we combine three-dimensional echo planar imaging (3D-EPI) with controlled aliasing to substantially increase temporal resolution in whole-brain functional MRI (fMRI) while minimizing geometry-factor (g-factor) losses. Theory and Metho ...

Wiley-Blackwell2016

Glutathione deficit affects the integrity and function of the fimbria/fornix and anterior commissure in mice: relevance for schizophrenia

Rolf Gruetter, João Miguel das Neves Duarte, Yohan Van de Looij, Aline Monin, Alberto Corcoba, Kim Do

BACKGROUND: Structural anomalies of white matter (WM) are found in various brain regions of patients with schizophrenia, bipolar and other psychiatric disorders, but the causes at cellular and molecular levels remain unclear. Oxidative stress and redox dys ...

Oxford Univ Press2016

Early detection of human glioma sphere xenografts in mouse brain using diffusion MRI at 14.1 T

Rolf Gruetter, Hongxia Lei

Glioma models have provided important insights into human brain cancers. Among the investigative tools, MRI has allowed their characterization and diagnosis. In this study, we investigated whether diffusion MRI might be a useful technique for early detecti ...

Wiley-Blackwell2016

N-Acetyl-Cysteine in a double-blind randomized placebo-controlled trial: Towards biomarker guided treatment in early psychosis

Rolf Gruetter, Lijing Xin, Kim Do

Wiley-Blackwell2016

A double-quadrature radiofrequency coil design for proton-decoupled carbon-13 magnetic resonance spectroscopy in humans at 7T

Eulalia Serés Roig, Rolf Gruetter, Lijing Xin, Guillaume Donati, Özlem Ipek

Purpose Carbon-13 magnetic resonance spectroscopy (13C-MRS) is challenging because of the inherent low sensitivity of 13C detection and the need for radiofrequency transmission at the 1H frequency while receiving the 13C signal, the latter requiring electr ...

Wiley-Blackwell2015

In Vivo Longitudinal (1)H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T

Rolf Gruetter, Cristina Ramona Cudalbu, Mélanie Craveiro

In vivo (1)H MR spectroscopy allows the non invasive characterization of brain metabolites and it has been used for studying brain metabolic changes in a wide range of neurodegenerative diseases. The prion diseases form a group of fatal neurodegenerative d ...

Springer Verlag2015

Single acquisition electrical property mapping based on relative coil sensitivities: A proof-of-concept demonstration

Rolf Gruetter, José Pedro Rebelo Ferreira Marques, Özlem Ipek

All methods presented to date to map both conductivity and permittivity rely on multiple acquisitions to compute quantitatively the magnitude of radiofrequency transmit fields, B1+. In this work, we propose a method to compute both conductivity and permitt ...

Wiley-Blackwell2015

A Modulated Closed Form solution for Quantitative Susceptibility Mapping - A thorough evaluation and comparison to iterative methods based on edge prior knowledge

Rolf Gruetter, Yves Wiaux, José Pedro Rebelo Ferreira Marques, Diana Khabipova

The aim of this study is to perform a thorough comparison of quantitative susceptibility mapping (QSM) techniques and their dependence on the assumptions made. The compared methodologies were: two iterative single orientation methodologies minimizing the l ...

Elsevier2015

Fasting-induced changes of hepatic lipid and carbohydrate stores in the absence of GLUT2

Rolf Gruetter, Hongxia Lei, Ana Francisca Leal Silva Soares

Wiley-Blackwell2015

Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients

Jean-Philippe Thiran, Patric Hagmann, Philipp Baumann, Rolf Gruetter, Lijing Xin, Alessandra Griffa, Aline Monin, Kim Do

Schizophrenia pathophysiology implies both abnormal redox control and dysconnectivity of the prefrontal cortex, partly related to oligodendrocyte and myelin impairments. As oligodendrocytes are highly vulnerable to altered redox state, we investigated the ...

Nature Publishing Group2015

Stroking or Buzzing? A Comparison of Somatosensory Touch Stimuli Using 7 Tesla fMRI

Roberto Martuzzi, Rolf Gruetter, Wietske Van der Zwaag

Studying body representations in the brain helps us to understand how we humans relate to our own bodies. The in vivo mapping of the somatosensory cortex, where these representations are found, is greatly facilitated by the high spatial resolution and high ...

Public Library of Science2015

Physiological noise in human cerebellar fMRI

Rolf Gruetter, Wietske Van der Zwaag, Denis Butticaz, João Pedro Forjaco Jorge

Objectives To compare physiological noise contributions in cerebellar and cerebral regions of interest in high-resolution functional magnetic resonance imaging (fMRI) data acquired at 7T, to estimate the need for physiological noise removal in cerebellar f ...

Springer Verlag2015

Direct noninvasive estimation of myocardial tricarboxylic acid cycle flux in vivo using hyperpolarized 13C magnetic resonance

Arnaud Comment, Rolf Gruetter, Hongxia Lei, Tian Cheng, Josefina Adriana Maria Bastiaansen

BACKGROUND: The heart relies on continuous energy production and imbalances herein impair cardiac function directly. The tricarboxylic acid (TCA) cycle is the primary means of energy generation in the healthy myocardium, but direct noninvasive quantificati ...

Elsevier2015

Imaging of prolonged BOLD response in the somatosensory cortex of the rat

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

Blood oxygenation level-dependent (BOLD) functional MRI is a widely employed methodology in experimental and clinical neuroscience, although its nature is not fully understood. To gain insights into BOLD mechanisms and take advantage of the new functional ...

Wiley-Blackwell2015

Brain energy metabolism measured by 13C magnetic resonance spectroscopy in vivo upon infusion of [3-13C]lactate

Rolf Gruetter, João Miguel das Neves Duarte, Freya-Merret Girault

The brain uses lactate produced by glycolysis as an energy source. How lactate originated from the blood stream is used to fuel brain metabolism is not clear. The current study measures brain metabolic fluxes and estimates the amount of pyruvate that becom ...

Wiley-Blackwell2015

Towards high-quality simultaneous EEG-fMRI at 7T: Detection and reduction of EEG artifacts due to head motion

Rolf Gruetter, Wietske Van der Zwaag, João Pedro Forjaco Jorge, Patricia Figueiredo

The enhanced functional sensitivity offered by ultra-high field imaging may significantly benefit simultaneous EEG-fMRI studies, but the concurrent increases in artifact contamination can strongly compromise EEG data quality. In the present study, we focus ...

Elsevier2015

Metabolic flux analysis of hepatic mitochondrial oxidation of hyperpolarized [1-13C] and [2-13C] pyruvate in vivo

Arnaud Comment, Rolf Gruetter, Josefina Adriana Maria Bastiaansen, Emine Can, Hikari Ananda Infinity Yoshihara

2015

Radical-free mixture of co-polarized 13C metabolites for probing separate biochemical pathways in vivo by hyperpolarized 13C MR

Arnaud Comment, Rolf Gruetter, Josefina Adriana Maria Bastiaansen, Andrea Capozzi, Hikari Ananda Infinity Yoshihara

2015

Noninvasive assessment of presymptomatic and symptomatic metabolic changes in the brain and brainstem of an ALS mouse model

Rolf Gruetter, Hongxia Lei

Wiley-Blackwell2015

Parallel imaging with phase scrambling

Rolf Gruetter, Daniel Gallichan

PURPOSE: Most existing methods for accelerated parallel imaging in MRI require additional data, which are used to derive information about the sensitivity profile of each radiofrequency (RF) channel. In this work, a method is presented to avoid the acquisi ...

Wiley-Blackwell2015

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