Recherche

Afficher tous les résultats pour

Accueil

Personne

Rolf Gruetter

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (418)

Clinical Neuroimaging Using 7 T MRI: Challenges and Prospects

François Lazeyras, Rolf Gruetter, Lijing Xin, Özlem Ipek, Pascal Martelli

The aim of this article is to illustrate the principal challenges, from the medical and technical point of view, associated with the use of ultrahigh field (UHF) scanners in the clinical setting and to present available solutions to circumvent these limita ...

2018

Mapping and characterization of positive and negative BOLD responses to visual stimulation in multiple brain regions at 7T

Rolf Gruetter, Wietske Van der Zwaag, João Pedro Forjaco Jorge, Patricia Figueiredo

External stimuli and tasks often elicit negative BOLD responses in various brain regions, and growing experimental evidence supports that these phenomena are functionally meaningful. In this work, the high sensitivity available at 7T was explored to map an ...

Wiley2018

An Add-On Trial With N-Acetyl-Cysteine (Nac) In Early Psychosis Patients: Towards Biomarker Guided Treatment

Rolf Gruetter, Lijing Xin, Kim Do

Oxford University Pres2018

Metabolic And Transcriptional Profiles Of Gbm Invasion: Comparison Of Patients And Paired Patient Derived Xenografts Using1H Magnetic Resonance Spectroscopy And Imaging (7T And 14T) And Rna-Sequencing

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu, Mario Gaetano Lepore, Marta Lai

OXFORD UNIV PRESS INC2018

Increased hepatic fatty acid polyunsaturation precedes ectopic lipid deposition in the liver in adaptation to high-fat diets in mice

Rolf Gruetter, João Miguel das Neves Duarte, Ana Francisca Leal Silva Soares

2018

Astrocytic and neuronal oxidative metabolism are coupled to the rate of glutamate-glutamine cycle in the tree shrew visual cortex

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay, Anne Catherine Clerc, Gregor Rainer

Astrocytes play an important role in glutamatergic neurotransmission, namely by clearing synaptic glutamate and converting it into glutamine that is transferred back to neurons. The rate of this glutamate–glutamine cycle (VNT) has been proposed to couple t ...

Wiley-Blackwell2018

In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose

Bernard Lanz, Rolf Gruetter, Carole Poitry-Yamate, Cristina Ramona Cudalbu, Marta Lai, Corina Mihaela Berset

In vivo (13)C magnetic resonance spectroscopy (MRS) enables the investigation of cerebral metabolic compartmentation while, e.g. infusing (13)C-labeled glucose. Metabolic flux analysis of (13)C turnover previously yielded quantitative information of glutam ...

2018

Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized C-13 magnetic resonance

Arnaud Comment, Rolf Gruetter, Mor-Miri Mishkovsky

The mammalian brain relies primarily on glucose as a fuel to meet its high metabolic demand. Among the various techniques used to study cerebral metabolism, C-13 magnetic resonance spectroscopy (MRS) allows following the fate of C-13-enriched substrates th ...

Springer Nature2017

Coupling of the glutamate-glutamine cycle rate with both glial and neuronal oxidative metabolism in the visual cortex of the Tupaia belangeri

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay, Anne Catherine Clerc

Sage Publications Inc2017

Redox dysregulation in schizophrenia pathophysiology: add-on trial with N-acetylcysteine (NAC) in early psychosis patients

Rolf Gruetter, Lijing Xin, Kim Do

Elsevier Science Bv2017

In vivo detection of hypothalamic glucose metabolism in HFD and regular fed mice

Rolf Gruetter, Hongxia Lei, Antoine Timothée Cherix, Blanca Lizarbe Serra

Sage Publications Inc2017

Influence of physiological noise on accelerated 2D and 3D resting state functional MRI data at 7 T

Rolf Gruetter, Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques, João Pedro Forjaco Jorge, Olivier Benoit Thomas Reynaud

Physiological noise often dominates the blood-oxygen level-dependent (BOLD) signal fluctuations in high-field functional MRI (fMRI) data. Therefore, to optimize fMRI protocols, it becomes crucial to investigate how physiological signal fluctuations impact ...

Wiley-Blackwell2017

Altered glycogen metabolism in the brain of insulin-resistant Goto-Kakizaki rats: a 13C magnetic resonance spectroscopy study in V

Rolf Gruetter, João Miguel das Neves Duarte, Ana Francisca Leal Silva Soares

Wiley2017

Defining mitochondrial biomarkers and function using magnetic resonance spectroscopy at 14.1 Tesla in a mouse model of mood disorders

Rolf Gruetter, Hongxia Lei, Guillaume Donati, Antoine Timothée Cherix, Blanca Lizarbe Serra

Sage Publications Inc2017

Sexual dimorphism in hepatic lipids is associated with the evolution of metabolic status in mice

Rolf Gruetter, Marc Moniatte, Hongxia Lei, Jonathan Paz Montoya, Ana Francisca Leal Silva Soares

Ectopic lipid accumulation in the liver is implicated in metabolic disease in an age- and sex-dependent manner. The role of hepatic lipids has been well established within the scope of metabolic insults in mice, but has been insufficiently characterized un ...

Wiley-Blackwell2017

Investigating mitochondrial biomarkers and function using MRS at 14.1 Tesla in a mouse model of mood disorders

Rolf Gruetter, Hongxia Lei, Guillaume Donati, Antoine Timothée Cherix, Blanca Lizarbe Serra

Wiley2017

Energy metabolism in the rat cortex under thiopental anaesthesia measured

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

Barbiturates, commonly used as general anaesthetics, depress neuronal activity and thus cerebral metabolism. Moreover, they are likely to disrupt the metabolic support of astrocytes to neurons, as well as the uptake of nutrients from circulation. By employ ...

Wiley-Blackwell2017

How Energy Metabolism Supports Cerebral Function: Insights from 13C Magnetic Resonance Studies In vivo

Rolf Gruetter, João Miguel das Neves Duarte, Sarah Catherine Sonnay

Cerebral function is associated with exceptionally high metabolic activity, and requires continuous supply of oxygen and nutrients from the blood stream. Since the mid-20th century the idea that brain energy metabolism is coupled to neuronal activity has e ...

Frontiers Research Foundation2017

Comparison diffusion behavior of metabolites in brains of congenital portal systemic shunt and healthy mice in vivo at 14.1 t

Nicolas Kunz, Rolf Gruetter, Hongxia Lei, Masoumeh Dehghani Moghadam

Wiley2017

Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex

Rolf Gruetter, João Miguel das Neves Duarte, Alberto Corcoba, Kim Do

Environmental stress can interact with genetic predisposition to increase the risk of developing psychopathology. In this work, we tested the hypothesis that social isolation stress interacts with impaired glutathione synthesis and have cumulative effects ...

Wiley-Blackwell2017

Page 4 sur 21