Recherche

Afficher tous les résultats pour

Accueil

Personne

Sandrine Gerber

Cette personne a quitté l’EPFL

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (97)

Page 2 sur 5

Gd3+-Functionalized Lithium Niobate Nanoparticles for Dual Multiphoton and Magnetic Resonance Bioimaging

Marinella Mazzanti, Sandrine Gerber, Anne-Sophie Chauvin, Luigi Bonacina, Katarzyna Pierzchala, Ileana Ozana Jelescu, Jérémy Vuilleumier, Raphaël Jovita De Matos, Laura Camille Louise Nicolle, Adrian Stefan Gheata, Dario Diviani

Harmonic nanoparticles (HNPs) have emerged as appealing exogenous probes for optical bioimaging due to their distinctive features such as long-term photostability and spectral flexibility, allowing multiphoton excitation in the classical (NIR-I) and extend ...

2022

The prolyl-aminodipeptidases and their inhibitors as therapeutic targets for fibrogenic disorders

Sandrine Gerber

Many biologically active peptides are protected from general proteolytic degradation by evolutionary conserved prolines (Pro), due to conformational constraints imposed by the Pro residue. Thus the biological importance of prolyl-specific peptidases points ...

2009

Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-Cadherin interaction and prolong function of transplanted encapsulated islets in mice

Jutta Christine Wandrey, Sandrine Gerber, Redouan Mahou

Background: Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets. Methods: Human MSC ...

Biomed Central Ltd2017

Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles

Sandrine Gerber, Luigi Bonacina, Solène Marcelle Françoise Marie Passemard, Davide Städler

Bismuth Ferrite (BFO) nanoparticles (BFO-NP) display interesting optical (nonlinear response) and magnetic properties which make them amenable for bio-oriented diagnostic applications as intra- and extra membrane contrast agents. Due to the relatively rece ...

Elsevier2015

A Short and Convenient Synthesis of 1-Deoxymannojirimycin (DMJ) and N-oxy-Analogues from D-Fructose

Pierre Vogel, Sandrine Gerber

The ketonitrone 8 was prepared from D-fructose as an inexpensive starting material, and was used in a stereoselective synthesis of 1-deoxymannojirimycin (4), its previously unknown N-hydroxy analogue 15, as well as the polyhydroxylated ketonitrone 14. The ...

2009

A DNA biosensors-based microfluidic platform for attomolar real-time detection of unamplified SARS-CoV-2 virus

Sandrine Gerber, Mounir Driss Mensi, Céline Marie Anne Journot, Perrine Agnes Edith Robin, Igor Stefanini, Lucas Mayoraz

The emergence of the coronavirus 2019 (COVID-19) arose the need for rapid, accurate and massive virus detection methods to control the spread of infectious diseases. In this work, a device, deployable in non-medical environments, has been developed for the ...

2023

Modulating the Surface Properties of Lithium Niobate Nanoparticles by Multifunctional Coatings Using Water-in-Oil Microemulsions

Sandrine Gerber, Alessandra Spada, Adrian Stefan Gheata

Inorganic nanoparticles (NPs) have emerged as promising tools in biomedical applications, owing to their inherent physicochemical properties and their ease of functionalization. In all potential applications, the surface functionalization strategy is a key ...

2023

Observations of Pauli paramagnetic effects on the flux line lattice in CeCoIn5

Sandrine Gerber, Joël Mesot, Jonathan White

From small-angle neutron scattering studies of the flux line lattice (FLL) in CeCoIn5, with magnetic field applied parallel to the crystal c-axis, we obtain the field and temperature dependence of the FLL form factor (FF), which is a measure of the spatial ...

2010

Synthesis of bone-like structured foams

Sandrine Gerber, Françoise Borcard

Here we present a processing route to produce multi-structured ceramic foams based on the combination of particle-stabilized foams with polymeric sponges to produce positive and negative templating structures. Polyester sponges are infiltrated with freshly ...

Elsevier Sci Ltd2013

Synthetic calibrators for the analysis of sulfoconjugated metanephrines in urine: hydrolysis conditions revisited

Sandrine Gerber, Jonathan Simonin

Background: The quantification of total (free + sulfated) metanephrines in urine is recommended to diagnose pheochromocytoma. Urinary metanephrines include metanephrine itself, normetanephrine and methoxytyramine, mainly in the form of sulfate conjugates ( ...

Elsevier2012

Functionalized pyrrolidines as alpha-mannosidase inhibitors and growth inhibitors of human glioblastoma and melanoma cells

Pierre Vogel, Sandrine Gerber, Sylvain Favre, Hélène Fiaux

New substituted pyrrolidine-3,4-diol derivatives were prepared from D-(-)- and L-(+)-phenyl glycinol. The influence of the configuration and the substitution of the lateral side chain of these derivatives on the inhibition of 25 commercial glycosidases wer ...

2005

Quantum and thermal ionic motion, oxygen isotope effect, and superexchange distribution in La2CuO4

Vera Irina Schnells, Henrik Moodysson Rønnow, Sandrine Gerber, Bruce Normand, Bastien Dalla Piazza

We study the zero-point and thermal ionic motion in La2CuO4 by means of high-resolution neutron-diffraction experiments. Our results demonstrate anisotropic motion of O and, to a lesser extent, Cu ions, both consistent with the structure of coupled CuO6 oc ...

2014

Surface Modification of Biomaterials for Conjugation with Human Fetal Osteoblasts

Sandrine Gerber, Françoise Borcard, Davide Städler, Céline Marie Anne Journot, Phally Kong

Surface functionalization of hydroxyapatite (HA) and β-tricalcium phosphate (TCP) bioceramics with chemical ligands containing a pyrrogallol moiety was developed to improve the adhesion of bone cell precursors to the biomaterials. Fast and biocompatible co ...

Swiss Chemical Soc2013

FAP Targeting of Photosensitizer-Loaded Polymersomes for Increased Light-Activated Cell Killing

Sandrine Gerber

As current chemo- and photodynamic cancer therapies are associated with severe side effects due to a lack of specificity and to systemic toxicity, innovative solutions in terms of targeting and controlled functionality are in high demand. Here, we present ...

American Chemical Society2024

Contribution of polymeric materials to progress in xenotransplantation of microencapsulated cells - A review

Sandrine Gerber, Jutta Christine Wandrey, Redouan Mahou, Solène Marcelle Françoise Marie Passemard, François Rémi Pierre Noverraz

Cell microencapsulation and subsequent transplantation of the microencapsulated cells require multidisciplinary approaches. Physical, chemical, biological, engineering, and medical expertise has to be combined. Several natural and synthetic polymeric mater ...

2016

Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR

Geoffrey Bodenhausen, Sandrine Gerber, Sami Jannin, Aurélien Bornet, Jonas Milani, Basile Vuichoud, Solène Marcelle Françoise Marie Passemard, Daniele Mammoli, Nicola Salvi, Roberto Buratto

Transverse and longitudinal relaxation times (T11 and T1) have been widely exploited in NMR to probe the binding of ligands and putative drugs to target proteins. We have shown recently that long-lived states (LLS) can be more sensitive to ligand binding. ...

Wiley-Blackwell2014

Multi-harmonic imaging in the second near-infrared window of nanoparticle-labeled stem cells as effective monitoring tool in tissue depth

Sandrine Gerber, Luigi Bonacina, Solène Marcelle Françoise Marie Passemard

In order to assess the therapeutic potential of cell-based strategies, it is of paramount importance to elaborate and validate new tools for monitoring the behavior of injected cells in terms of tissue dissemination and engraftment properties. Here, we app ...

American Chemical Society2017

Multicomponent Alginate-Derived Hydrogel Microspheres Presenting Hybrid Ionic-Covalent Network and Drug Eluting Properties

Sandrine Gerber, François Rémi Pierre Noverraz, Luca Szabó

The development of multifunctional encapsulation biomaterials could help the translation of cell‐based therapies into standard medical care. One of the major hurdles in the field of encapsulated cell transplantation is the current lack of materials present ...

Wiley-VHCA AG2020

Enzymatic desymmetrization of 1,1 '-methylenedi-[(1R,1 ' S,3R,3 ' S,5S,5 ' R)-3-hydroxy-8-oxabicyclo[3.2.1]-oct-6-ene-1-yl]: Novel precursors of long chain polyketides

Sandrine Gerber, Gérald Coste

meso-1,1'-Methylenedi[(1R,1'S,3R,3'S,5S,5'R)-3-hydroxy-S-oxabicyclo[3.2. 1]oct-6-ene-1-yl] 14 obtained through the [4+3]-cycloaddition of 2,T-methylenedifuran to oxyallyl cation, followed by reduction, has been desymmetrized by means of a lipase catalyzed ...

2005

Covalent cell surface functionalization of human fetal osteoblasts for tissue engineering

Sandrine Gerber, Françoise Borcard, Corinne Scaletta, Aurélien Godinat, Davide Städler

The chemical functionalization of cell-surface proteins of human primary fetal bone cells with hydrophilic bioorthogonal intermediates was investigated. Toward this goal, chemical pathways were developed for click reaction-mediated coupling of alkyne deriv ...

2011