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Meritxell Bach Cuadra

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Publications associées (113)

Connectome Mapper 3: A Flexible and Open-Source Pipeline Software for Multiscale Multimodal Human Connectome Mapping

Meritxell Bach Cuadra, Patric Hagmann, Sébastien Tourbier, Alessandra Griffa, Emeline Mullier, Joan Rue Queralt, Mustafa Anil Tuncel, Mikkel Schöttner

2022

A multi-scale probabilistic atlas of the human connectome

Meritxell Bach Cuadra, Patric Hagmann, Elena Najdenovska, Alessandra Griffa, Maxime Descoteaux

The human brain is a complex system that can be efficiently represented as a network of structural connectivity. Many imaging studies would benefit from such network information, which is not always available. In this work, we present a whole-brain multi-s ...

NATURE PORTFOLIO2022

Editorial: Computational Neuroimage Analysis Tools for Brain (Diseases) Biomarkers

Meritxell Bach Cuadra, Tim Bjørn Dyrby

FRONTIERS MEDIA SA2022

Through-Plane Super-Resolution With Autoencoders in Diffusion Magnetic Resonance Imaging of the Developing Human Brain

Meritxell Bach Cuadra, Hamza Kebiri, Gabriel Girard, Erick Jorge Canales Rodriguez

Fetal brain diffusion magnetic resonance images (MRI) are often acquired with a lower through-plane than in-plane resolution. This anisotropy is often overcome by classical upsampling methods such as linear or cubic interpolation. In this work, we employ a ...

FRONTIERS MEDIA SA2022

An automatic multi-tissue human fetal brain segmentation benchmark using the Fetal Tissue Annotation Dataset

Meritxell Bach Cuadra, Hamza Kebiri

It is critical to quantitatively analyse the developing human fetal brain in order to fully understand neurodevelopment in both normal fetuses and those with congenital disorders. To facilitate this analysis, automatic multi-tissue fetal brain segmentation ...

NATURE RESEARCH2021

GAMER-MRI in Multiple Sclerosis Identifies the Diffusion-Based Microstructural Measures That Are Most Sensitive to Focal Damage: A Deep-Learning-Based Analysis and Clinico-Biological Validation

Meritxell Bach Cuadra, Francesco La Rosa

Conventional magnetic resonance imaging (cMRI) in multiple sclerosis (MS) patients provides measures of focal brain damage and activity, which are fundamental for disease diagnosis, prognosis, and the evaluation of response to therapy. However, cMRI is ins ...

FRONTIERS MEDIA SA2021

MPRAGE to MP2RAGE UNI translation via generative adversarial network improves the automatic tissue and lesion segmentation in multiple sclerosis patients

Jean-Philippe Thiran, Meritxell Bach Cuadra, Cristina Granziera, Thomas Yu, Francesco La Rosa

Background and objective: Compared to the conventional magnetization-prepared rapid gradient-echo imaging (MPRAGE) MRI sequence, the specialized magnetization prepared 2 rapid acquisition gradient echoes (MP2RAGE) shows a higher brain tissue and lesion con ...

2021

Myelin and axon pathology in multiple sclerosis assessed by myelin water and multi-shell diffusion imaging

Meritxell Bach Cuadra, Francesco La Rosa

Damage to the myelin sheath and the neuroaxonal unit is a cardinal feature of multiple sclerosis; however, a detailed characterization of the interaction between myelin and axon damage in vivo remains challenging. ...

OXFORD UNIV PRESS2021

Chronic White Matter Inflammation and Serum Neurofilament Levels in Multiple Sclerosis

Meritxell Bach Cuadra, Francesco La Rosa

Objective To assess whether chronic white matter inflammation in patients with multiple sclerosis (MS) as detected in vivo by paramagnetic rim MRI lesions (PRLs) is associated with higher serum neurofilament light chain (sNfL) levels, a marker of neuroaxon ...

LIPPINCOTT WILLIAMS & WILKINS2021

Simulated Half-Fourier Acquisitions Single-shot Turbo Spin Echo (HASTE) of the Fetal Brain: Application to Super-Resolution Reconstruction

Meritxell Bach Cuadra, Patric Hagmann, Reto Meuli, Sébastien Tourbier, Tobias Kober, Hamza Kebiri, Tom Hilbert, Thomas Yu

Accurate characterization of in utero human brain maturation is critical as it involves complex interconnected structural and functional processes that may influence health later in life. Magnetic resonance imaging is a powerful tool complementary to the u ...

SPRINGER INTERNATIONAL PUBLISHING AG2021

Cortical lesion detection using FLAWS in multiple sclerosis

Meritxell Bach Cuadra, Francesco La Rosa

SAGE PUBLICATIONS LTD2021

An assessment of intra-scanner reproducibility of myelin-sensitive MRI measures

Meritxell Bach Cuadra, Cristina Granziera, Po-Jui Lu, Muhamed Barakovic, Lester Melie Garcia, Francesco La Rosa, Yi Wang

SAGE PUBLICATIONS LTD2021

CLaiMS-Net: cortical lesions assessment in multiple sclerosis patients via a convolutional neural network and a single 3T MRI acquisition

Jean-Philippe Thiran, Meritxell Bach Cuadra, Cristina Granziera, Po-Jui Lu, Muhamed Barakovic, Francesco La Rosa

SAGE PUBLICATIONS LTD2021

GAMER MRI: Gated-attention mechanism ranking of multi-contrast MRI in brain pathology

Meritxell Bach Cuadra, Francesco La Rosa

Introduction: During the last decade, a multitude of novel quantitative and semiquantitative MRI techniques have provided new information about the pathophysiology of neurological diseases. Yet, selection of the most relevant contrasts for a given patholog ...

2021

Automated assessment of paramagnetic rim lesions in multiple sclerosis patients with 3T and 7T MP2RAGE

Jean-Philippe Thiran, Meritxell Bach Cuadra, Bénédicte Marie Maréchal, Tobias Kober, Cristina Granziera, Francesco La Rosa

Paramagnetic rim lesions (PRL) in multiple sclerosis are chronic inflammatory lesions depicted in susceptibility-based MRI where high PRL lesion burden has been associated with a more aggressive disease course. As their visual detection is subjective and t ...

ISMRM2021

Quantitative Evaluation of Enhanced Multi-plane Clinical Fetal Diffusion MRI with a Crossing-Fiber Phantom

Meritxell Bach Cuadra, Gabriel Girard, Erick Jorge Canales Rodriguez, Marco Pizzolato

Diffusion Magnetic Resonance Imaging (dMRI) has become widely used to study in vivo white matter tissue properties noninvasively. However, fetal dMRI is greatly limited in Signal-to-Noise ratio and spatial resolution. Due to the uncontrollable fetal motion ...

SPRINGER INTERNATIONAL PUBLISHING AG2021

Automated detection of cortical lesions with single and multi-contrast 7T MRI

Jean-Philippe Thiran, Meritxell Bach Cuadra, Cristina Granziera, Francesco La Rosa

SAGE PUBLICATIONS LTD2021

Higher Order Spherical Harmonics Reconstruction of Fetal Diffusion MRI With Intensity Correction

Meritxell Bach Cuadra

We present a novel method for higher order reconstruction of fetal diffusion MRI signal that enables detection of fiber crossings. We combine data-driven motion and intensity correction with super-resolution reconstruction and spherical harmonic parametris ...

Institute of Electrical and Electronics Engineers2020

Improved susceptibility-weighted imaging for high contrast and resolution thalamic nuclei mapping at 7T

Meritxell Bach Cuadra, Elena Najdenovska, José Pedro Rebelo Ferreira Marques, Frédéric Gretsch, João Pedro Forjaco Jorge, Daniel Gallichan, Constantin Tuleasca

Purpose The thalamus is an important brain structure and neurosurgical target, but its constituting nuclei are challenging to image non-invasively. Recently, susceptibility-weighted imaging (SWI) at ultra-high field has shown promising capabilities for tha ...

Wiley2020

An Anatomically-Informed 3D CNN for Brain Aneurysm Classification with Weak Labels

Meritxell Bach Cuadra

A commonly adopted approach to carry out detection tasks in medical imaging is to rely on an initial segmentation. However, this approach strongly depends on voxel-wise annotations which are repetitive and time-consuming to draw for medical experts. An int ...

Cham2020

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