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Meritxell Bach Cuadra

Cette personne a quitté l’EPFL

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Publications associées (112)

Page 1 sur 6

Partial-volume modeling reveals reduced gray matter in specific thalamic nuclei early in the time course of psychosis and chronic schizophrenia

Meritxell Bach Cuadra, Patric Hagmann, Erick Jorge Canales Rodriguez

The structural complexity of the thalamus, due to its mixed composition of gray and white matter, make it challenging to disjoint and quantify each tissue contribution to the thalamic anatomy. This work promotes the use of partial-volume-based over probabi ...

Wiley2020

CVSnet: A machine learning approach for automated central vein sign assessment in multiple sclerosis

Reto Meuli, Tobias Kober, Meritxell Bach Cuadra, Cristina Granziera, Jonas Richiardi, Francesco La Rosa, João Pedro Forjaco Jorge

The central vein sign (CVS) is an efficient imaging biomarker for multiple sclerosis (MS) diagnosis, but its application in clinical routine is limited by inter-rater variability and the expenditure of time associated with manual assessment. We describe a ...

2020

Model-informed machine learning for multi-component T2 relaxometry

Jean-Philippe Thiran, Tobias Kober, Meritxell Bach Cuadra, Tom Hilbert, Erick Jorge Canales Rodriguez, Cristina Granziera, Muhamed Barakovic, Marco Pizzolato, Elda Fischi Gomez, Thomas Yu, Gian Franco Piredda

Recovering the distribution from multi-echo magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this work, we propose to comb ...

2020

Fluid and White Matter Suppression New Sensitive 3 T Magnetic Resonance Imaging Contrasts for Cortical Lesion Detection in Multiple Sclerosis

Meritxell Bach Cuadra, Francesco La Rosa

Objective Cortical lesions are common in multiple sclerosis (MS), but their visualization is challenging on conventional magnetic resonance imaging. The uniform image derived from magnetization prepared 2 rapid acquisition gradient echoes (MP2RAGE(uni)) de ...

LIPPINCOTT WILLIAMS & WILKINS2022

Episodic memory decline in Parkinson' s disease: relation with white matter hyperintense lesions and influence of quantification method

Tobias Kober, Meritxell Bach Cuadra, Bénédicte Marie Maréchal

The relation of white matter hyperintense lesions to episodic memory impairment in patients with Parkinson's disease (PD) is still controversial. We aimed at evaluating the relation between white matter hyperintense lesions and episodic memory decline in p ...

SPRINGER2019

Bi-planar 2D-to-3D Registration in Fourier Domain for Stereoscopic X-Ray Motion Tracking

Jean-Philippe Thiran, Kamiar Aminian, Meritxell Bach Cuadra, Benoît Le Callennec, Dominique Zosso

In this paper we present a new method to track bone movements in stereoscopic X-ray image series of the knee joint. The method is based on two different X-ray image sets: a rotational series of acquisitions of the still subject knee that will allow the tom ...

2008

Streamline RimNet: Tools for Automatic Classification of Paramagnetic Rim Lesions in MRI of Multiple Sclerosis

Joe Najm, Meritxell Bach Cuadra, Cristina Granziera, Francesco La Rosa

This site provides two software tools related to "RimNet: A deep 3D multimodal MRI architecture for paramagnetic rim lesion assessment in multiple sclerosis" by Barquero et al. NeuroImage: Clinical (2020). People using in part or f ...

Zenodo2023

Chronic White Matter Inflammation and Serum Neurofilament Levels in Multiple Sclerosis

Meritxell Bach Cuadra, Francesco La Rosa

Objective To assess whether chronic white matter inflammation in patients with multiple sclerosis (MS) as detected in vivo by paramagnetic rim MRI lesions (PRLs) is associated with higher serum neurofilament light chain (sNfL) levels, a marker of neuroaxon ...

LIPPINCOTT WILLIAMS & WILKINS2021

GAMER MRI: Gated-attention mechanism ranking of multi-contrast MRI in brain pathology

Meritxell Bach Cuadra, Francesco La Rosa

Introduction: During the last decade, a multitude of novel quantitative and semiquantitative MRI techniques have provided new information about the pathophysiology of neurological diseases. Yet, selection of the most relevant contrasts for a given patholog ...

2021

A Multimodal Evaluation Method for Medical Image Segmentation

Meritxell Bach Cuadra

Evaluation of segmentation methods is a crucial aspect in image processing, especially in the medical imaging field, where small differences between segmented regions in the anatomy can be of paramount importance. Usually, segmentation evaluation is based ...

2009

A dataset of synthetic, maturation-informed magnetic resonance images of the human fetal brain

Andrés Le Boeuf Fló, Meritxell Bach Cuadra

Magnetic resonance imaging (MRI) is a powerful modality for investigating abnormal developmental patterns in utero. However, since it is not the first-line diagnostic tool in this sensitive population, data remain scarce and heterogeneous across scanners a ...

2025

Pretherapeutic resting-state fMRI profiles are associated with MR signature volumes after stereotactic radiosurgical thalamotomy for essential tremor

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Meritxell Bach Cuadra, Constantin Tuleasca, Thomas William Arthur Bolton, Adrien Jean Régis Maurice Hilaire

OBJECTIVE Essential tremor (ET) is the most common movement disorder. Drug-resistant ET can benefit from standard stereotactic deep brain stimulation or radiofrequency thalamotomy or, alternatively, minimally invasive techniques, including stereotactic rad ...

AMER ASSOC NEUROLOGICAL SURGEONS2018

Quantification in Musculoskeletal Imaging Using Computational Analysis and Machine Learning: Segmentation and Radiomics

Meritxell Bach Cuadra

Although still limited in clinical practice, quantitative analysis is expected to increase the value of musculoskeletal (MSK) imaging. Segmentation aims at isolating the tissues and/or regions of interest in the image and is crucial to the extraction of qu ...

THIEME MEDICAL PUBL INC2020

How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification Index

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer

Cortical folding (gyrification) is determined during the first months of life, so that adverse events occurring during this period leave traces that will be identifiable at any age. As recently reviewed by Mangin and colleagues2, several methods exist to q ...

2012

Longitudinal analysis of white matter and cortical lesions in multiple sclerosis

Tobias Kober, Meritxell Bach Cuadra, Cristina Granziera

Purpose: The goals of this study were to assess the performance of a novel lesion segmentation tool for longitudinal analyses, as well as to validate the generated lesion progression map between two time points using conventional and non-conventional MR se ...

2019

Automated Detection and Segmentation of Multiple Sclerosis Lesions Using Ultra-High-Field MP2RAGE

Tobias Kober, Meritxell Bach Cuadra, Cristina Granziera, Kieran O'Brien

Objectives The aim of this study was to develop a new automated segmentation method of white matter (WM) and cortical multiple sclerosis (MS) lesions visible on magnetization-prepared 2 inversion-contrast rapid gradient echo (MP2RAGE) images acquired at 7 ...

LIPPINCOTT WILLIAMS & WILKINS2019

MBIS: Multivariate Bayesian Image Segmentation tool

Jean-Philippe Thiran, Meritxell Bach Cuadra, Subrahmanyam Venkata Ravi Mohana Sai Gorthi

We present MBIS (Multivariate Bayesian Image Segmentation tool), a clustering tool based on the mixture of multivariate normal distributions model. MBIS supports multichannel bias field correction based on a B-spline model. A second methodological novelty ...

Elsevier Ireland Ltd2014

An Ultra-High Field Study of Cerebellar Pathology in Early Relapsing-Remitting Multiple Sclerosis Using MP2RAGE

Tobias Kober, Meritxell Bach Cuadra, Cristina Granziera, Gunnar Krüger, Alexis Roche, Guillaume Bonnier, Kieran O'Brien, Pavel Falkovskiy

Objectives: The aim of this study was to study focal cerebellar pathology in early stages of multiple sclerosis (MS) using ultra-high-field magnetization-prepared 2 inversion-contrast rapid gradient-echo (7T MP2RAGE). Materials and Methods: Twenty early-st ...

Lippincott, Williams & Wilkins2017

Brain Surface Segmentation of Magnetic Resonance Images of the Fetus

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer, Nawal Houhou, Dominique Zosso

In this work we present a method for the image analysis of Magnetic Resonance Imaging (MRI) of fetuses. Our goal is to segment the brain surface from multiple volumes (axial, coronal and sagittal acquisitions) of a fetus. To this end we propose a two-step ...

2008

Normalization of aberrant pretherapeutic dynamic functional connectivity of extrastriate visual system in patients who underwent thalamotomy with stereotactic radiosurgery for essential tremor: a resting-state functional MRI study

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Meritxell Bach Cuadra, Constantin Tuleasca, Thomas William Arthur Bolton

OBJECTIVE The tremor circuitry has commonly been hypothesized to be driven by one or multiple pacemakers within the cerebello-thalamo-cortical pathway, including the cerebellum, contralateral motor thalamus, and primary motor cortex. However, previous stud ...

2020