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Dominique Pioletti

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Publications associées (190)

Controlled release from a mechanically-stimulated thermosensitive self-heating composite hydrogel

Dominique Pioletti, Harm-Anton Klok, Mohamadreza Nassajian Moghadam, Vitaliy Kolesov

Temperature has been extensively explored as a trigger to control the delivery of a payload from environment-sensitive polymers. The need for an external heat source only allows limited spatiotem- poral control over the delivery process. We propose a new a ...

Elsevier Sci Ltd2014

Mechanical Properties Of A Photopolymerizable Hydrogel For Intervertebral Disc Replacement

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi

We report on the modelling and experimental validation of a photopolymerizable hydrogel for a Nucleus Pulposus replacement. ...

De Gruyter2013

Cartilage self-heating contributes to chondrogenic expression

Dominique Pioletti, Arne Christian Vogel, Philippe Abdel Sayed, Mohamadreza Nassajian Moghadam

Articular cartilage is a soft tissue showing inelastic properties. Under cyclic loading, inelastic materials may dissipate mechanical energy into heat. In knee cartilage, due to an intrinsic reduced heat convection related to its avascularity, a local temp ...

European Cells & Materials Ltd2013

Importance of the subscapularis muscle after total shoulder arthroplasty

Dominique Pioletti, Alexandre Terrier, Xabier Larrea, Alain Farron, Valérie Hélène Emilie Malfroy Camine

Background: The rotator cuff muscles are the main stabilizer of the glenohumeral joint. After total shoulder arthroplasty using anterior approaches, a dysfunction of the subscapularis muscle has been reported. In the present paper we tested the hypothesis ...

Elsevier Sci Ltd2013

Activities of daily living with reverse prostheses: importance of scapular compensation for functional mobility of the shoulder

Dominique Pioletti, Alexandre Terrier, Alain Farron, Patricia Scheuber

Hypothesis: The nonanatomical design of reverse shoulder prostheses induce medial displacement of the center of rotation, impingements and may reduce the mobility of the shoulder. The aim of this study is to test the hypothesis that during activities of da ...

Elsevier2013

Multi-Scale Modeling Of Photopolymerization For Medical Hydrogel-Implant Design

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Salma Farahi

We report on the modeling of a photopolymerizable hydrogel and its application as a replacement of the interior of the intervertebral disc (so called Nucleus Pulposus). The hydrogel is initially injected in its liquid form and then photopolymerized via a s ...

Spie-Int Soc Optical Engineering2013

Response to Letter to the Editor: Comment on "injectable calcium phosphate cement for augmentation around cancellous bone screws. In vivo biomechanical studies"

Dominique Pioletti

Elsevier Sci Ltd2013

Capillary-valve-based platform towards cell-on-chip mechanotransduction assays

Hicham Majd, Dominique Pioletti, Christophe Yamahata, Martinus Gijs, Tanja Cloé Hausherr, Arnaud Müller

Reliable in vitro models are required to understand the ability of cells to respond and adapt to mechanical stimuli. To mimic and interface with the microenvironment, lab-on-a-chip devices and microelectromechanical systems (MEMS) provide excellent options ...

Elsevier2013

Effect of a pathological scapular tilt after total shoulder arthroplasty

Dominique Pioletti, Alexandre Terrier, Alain Farron

Total shoulder arthroplasty (TSA) is an accepted and most successfully used treatment for different shoulder pathologies. Different risk factors for the failure of the prosthesis are known. A pathological scapular orientation, observed in elderly people or ...

Taylor & Francis2013

Integration of mechanotransduction concepts in bone tissue engineering

Dominique Pioletti

Mechanical stimulus has been identified for a long time as a key player in the adaptation of the musculo-skeletal tissues to their function. Mechanical loading is then an intrinsic variable to be considered when new developments are proposed in bone tissue ...

Taylor & Francis2013

A flow sensing model for mesenchymal stromal cells using morphogen dynamics

Dominique Pioletti, Alexandre Terrier, Miguel Gortchacow

The differentiation of mesenchymal stromal cells has been shown to be af- fected by many parameters such as morphogens, flow rate, medium viscosity, and shear stress when exposed to fluid flow. The mechanism by which these cells sense their environment is ...

Elsevier2013

Dissipation Can Act as a Mechanobiological Signal in Cartilage Differentiation

Dominique Pioletti, Arne Christian Vogel, Philippe Abdel Sayed

Knee cartilage is a soft tissue having viscoelastic properties. Under cyclic loadings, viscoelastic materials dissipate mechanical loadings through heat generation. In knee cartilage, this heat might not be convected because of the tissue avascularity, res ...

ASME2013

Composite hydrogels

Dominique Pioletti, Pierre-Etienne Bourban, Arne Christian Vogel

The present invention relates to reinforced composite hydrogel based on a polymer blend and comprising a network of fibres, said polymer blend comprising UV sensitive molecules. It also relates to a process for preparing the reinforced composite hydrogel a ...

2012

Development of a nano-composite drug eluting bone plug enhancing fixation of screws in low quality bone

Dominique Pioletti, Raphaël Rodolphe Obrist, Ulrike Kettenberger

Wiley-Blackwell2012

Synthesis and photopolymerization of Tween 20 Methacrylate/N-vinyl-2-Pyrrolidone blend

Dominique Pioletti, Pierre-Etienne Bourban, John Christopher Plummer, Ana Borges de Couraça

Poly(oxyethylene 20 sorbitan) monolaurate (Tween® 20) methacrylates were synthesized by coupling methacryloyl chloride (MeOCl) to Tween 20 in the presence of 4-(N,N-dimethylamino) pyridine, using THF as a solvent, in order to investigate their suitability ...

Elsevier Science Bv2012

Injectable calcium phosphate cement for augmentation around cancellous bone screws. In vivo biomechanical studies

Dominique Pioletti, Vincent Stadelmann

In lower cancellous apparent bone density, it can be difficult to achieve adequate screw fixation and hence stable fracture fixation. Different strategies have been proposed, one of them is through augmentation using calcium phosphate cement in the region ...

Elsevier2012

Epiphyseal chondro-progenitors provide a stable cell source for cartilage cell therapy

Dominique Pioletti, Corinne Scaletta, Lee Ann Laurent-Applegate, Salim Elias Darwiche

Articular cartilage regeneration poses particularly tough challenges for implementing cell-‐based therapies. Many cell types have been investigated looking for a balanced combination of responsiveness and stability, yet techniques are still far from defin ...

2012

Importance of polyethylene thickness in total shoulder arthroplasty: A finite element analysis

Dominique Pioletti, Alexandre Terrier, Alain Farron, Vittoria Brighenti

Background: Articular surfaces reconstruction is essential in total shoulder arthroplasty. Because of the limited glenoid bone support, thin glenoid component could improve anatomical reconstruction, but adverse mechanical effects might appear. Methods: Wi ...

Elsevier2012

Simultaneous and multisite measure of micromotion, subsidence and gap to evaluate femoral stem stability

Dominique Pioletti, Alexandre Terrier, Miguel Gortchacow

The initial stability of cementless femoral components is crucial for the long-term success of total hip arthroplasty. This has been reported in animal and clinical studies. Until now, the stability was evaluated by the measurement of relative micromotion ...

Elsevier2012

Human epiphyseal chondro-progenitors provide a stable cell source for cartilage repair and regeneration

Dominique Pioletti, Corinne Scaletta

Wiley-Blackwell2012

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