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Dominique Pioletti

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Publications associées (190)

3D Printing of Polymers with Hierarchical Continuous Porosity

Dominique Pioletti, Pierre-Etienne Bourban, Matteo Gregorio Modesto Marascio, Jens Antons

Cellular thermoplastic structures with multiscale porosity (1–300 µm microporosity to 0.3–10 mm macroporosity) are produced from an integrated approach of 3D printing by Fused Deposition Modeling printing and Supercritical CO2 Foaming. Porous strands and r ...

Wiley2017

A simulation framework for humeral head translations

Dominique Pioletti, Philippe Müllhaupt, Alexandre Terrier, Alain Farron, Ehsan Sarshari

Humeral head translations (HHT) play a crucial role in the glenohumeral (GH) joint function. The available shoulder musculoskeletal models developed based on inverse dynamics however fall short of predicting the HHT. This study aims at developing a simulat ...

2017

Development of an effective cell seeding technique: simulation, implementation and analysis of contributing factors

Dominique Pioletti, Lee Ann Laurent-Applegate, Naser Nasrollahzadeh Mamaghani

Cell seeding in a biomaterial is an important process for tissue engineering applications. It helps to modulate tissue formation or to control initial conditions for mechanobiological studies. The compression release-induced suction (CRIS) seeding techniqu ...

Mary Ann Liebert, Inc2017

Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair

Dominique Pioletti, Ting Zhu, Weiliang Shen, Jiayun Huang

Rotator cuff tear is one of the most common types of shoulder injuries, often resulting in pain and physical debilitation. Allogeneic tendon-derived decellularized matrices do not have appropriate pore size and porosity to facilitate cell infiltration, whi ...

Elsevier2017

Micromotion-induced peri-prosthetic fluid flow around a cementless femoral stem

Dominique Pioletti, Alexandre Terrier, Valérie Hélène Emilie Malfroy Camine

Micromotion-induced interstitial fluid flow at the bone-implant interface has been proposed to play an important role in aseptic loosening of cementless implants. High fluid velocities are thought to promote aseptic loosening through activation of osteocla ...

Taylor & Francis2017

Human bone progenitor cells for clinical application: what kind of immune reaction does fetal xenograft tissue trigger in immuno-competent rats?

Dominique Pioletti, Tanja Cloé Hausherr, Lee Ann Laurent-Applegate

The potential of human fetal bone cells for successful bone regeneration has been shown in vivo. In particular, it has been demonstrated that the seeding of these cells in porous poly-(L-lactic acid)/ ß-tricalcium phosphate scaffolds improved the bone form ...

Cognizant Communication Corp2017

Active Agent-Particle Combination Supporting Bone Regeneration

Dominique Pioletti, Ulrike Kettenberger

The invention provides for a bioactive composition comprising solid particles, such as e.g. calcium phosphate particles, loaded with an active agent, preferably an osteoconductive/osteoinductive agent or an anti-resorptive agent like a bisphosphonate. The ...

2017

Energy Dissipation as a Target in Cartilage Tissue Engineering Scaffold

Dominique Pioletti

Mary Ann Liebert, Inc2016

Stability enhancement using hyaluronic acid gels for delivery of human fetal progenitor tenocytes

Dominique Pioletti, Alain Farron, Corinne Scaletta, Lee Ann Laurent-Applegate, Anthony Grognuz

Tendon afflictions are very common, and their negative impact is high both at the workplace and in leisure activities. Tendinopathies are increasing in prevalence and can lead to tendon ruptures, where healing is a long process with outcomes that are often ...

2016

A photopolymerized composite hydrogel and surgical implanting tool for a nucleus pulposus replacement

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Nucleus pulposus replacements have been subjected to highly controversial discussions over the last 40 years. Their use has not yet resulted in a positive outcome to treat herniated disc or degenerated disc disease. The main reason is that not a single imp ...

Elsevier2016

Anti-microbial dendrimers against multidrug-resistant P. aeruginosa enhance the angiogenic effect of biological burn-wound bandages

Dominique Pioletti, Jean-Louis Reymond, Philippe Abdel Sayed, Lee Ann Laurent-Applegate, Paris Jafari

Multi-drug resistant Pseudomonas aeruginosa has increased progressively and impedes further regression in mortality in burn patients. Such wound infections serve as bacterial reservoir for nosocomial infections and are associated with signi cant morbidity ...

Nature Research2016

Experimental method to characterize the strain dependent permeability of tissue engineering scaffolds

Dominique Pioletti, Naser Nasrollahzadeh Mamaghani

Permeability is an overarching mechanical parameter encompassing the effects of porosity, pore size, and interconnectivity of porous structures. This parameter directly influences transport of soluble particles and indirectly regulates fluid pressure and v ...

Elsevier2016

Identification of elastic properties of human patellae using micro-finite element analysis

Dominique Pioletti, Alexandre Terrier, Adeliya Latypova

Current homogenized finite element (hFE) models of the patella lack a validated material law and mostly overlook trabecular anisotropy. The objective of this study was to identify the elastic constants of patellar trabecular bone. Using mu CT scans of 20 f ...

Elsevier2016

In-situ photopolymerized and monitored implants: successful application to an intervertebral disc replacement

Dominique Pioletti, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Photopolymerization is a common method to harden materials initially in a liquid state. A surgeon can directly trigger the solidification of a dental implant or a bone or tissue filler by using ultra-violet light. Traditionally, photopolymerization has bee ...

Spie-Int Soc Optical Engineering2016

A framework for forward-dynamics simulation of the human shoulder

Dominique Pioletti, Philippe Müllhaupt, Alexandre Terrier, Alain Farron, Ehsan Sarshari

A vast majority of the available biomechanical models of the human shoulder has been developed based on inverse dynamics, e.g. [1,2]. This imposes a number of limitations on their application. For instance, the glenohumeral joint is approximated as an idea ...

2016

Device for photoactivation and reaction monitoring

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Christophe Moser

The present invention relates to a device to photocure and/or photoactivate a photosensitive material. The device comprises several subsystems to transmit light towards an area of interest where a photosensitive material is applied as well as to collect li ...

2016

Full-field measurement of micromotion around a cementless femoral stem using micro-CT imaging and radiopaque markers

Dominique Pioletti, Alexandre Terrier, Valérie Hélène Emilie Malfroy Camine, Hannes Andreas Rüdiger

A good primary stability of cementless femoral stems is essential for the long-term success of total hip arthroplasty. Experimental measurement of implant micromotion with linear variable differential transformers is commonly used to assess implant primary ...

Elsevier2016

Biodegradable HEMA-based hydrogels with enhanced mechanical properties

Dominique Pioletti, Mohamadreza Nassajian Moghadam

Hydrogels are widely used in the biomedical field. Their main purposes are either to deliver biological active agents or to temporarily fill a defect until they degrade and are followed by new host tissue formation. However for this latter application, bio ...

Wiley-Blackwell2016

Improving hydrogels’ toughness by increasing the dissipative properties of their network

Dominique Pioletti, Mohamadreza Nassajian Moghadam

The weak mechanical performance and fragility of hydrogels limit their application as biomaterials for load bearing applications. The origin of this weakness has been explained by the low resistance to chains breakage composing the hydrogel and to the crac ...

Elsevier2015

Miniature probe for the delivery and monitoring of a photopolymerizable material

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Christophe Moser

Photopolymerization is a common method to cure materials initially in a liquid state, such as dental implants or bone or tissue fillers. Recent advances in the development of biocompatible gel- and cement-systems open up an avenue for in situ photopolymeri ...

SPIE Society of Photo-optical Instrumentation Engineers2015

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