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Concept

False positives and false negatives

Publications associées (28)

Tractography passes the test: Results from the diffusion-simulated connectivity (disco) challenge

Jean-Philippe Thiran, Alessandro Daducci, Erick Jorge Canales Rodriguez, Gabriel Girard, Marco Pizzolato, Ying-Chia Lin, Juan Luis Villarreal Haro

Estimating structural connectivity from diffusion-weighted magnetic resonance imaging is a challenging task, partly due to the presence of false-positive connections and the misestimation of connection weights. Building on previous efforts, the MICCAI-CDMR ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2023

Review on Uric Acid Recognition by MOFs with a Future in Machine Learning

Shaswati Mandal

Uric acid (UA) is produced from purine metabolism and serves as a prevalent biomarker for multiple diseases including cancer. Hyperuricemia or hypouricemia can cause multiple dysfunctions throughout the biological processes. Consequently, there is a pressi ...

Amer Chemical Soc2023

Assessing real-world gait with digital technology? Validation, insights and recommendations from the Mobilise-D consortium

Kamiar Aminian, Anisoara Ionescu, Abolfazl Soltani

Background: Although digital mobility outcomes (DMOs) can be readily calculated from real-world data collected with wearable devices and ad-hoc algorithms, technical validation is still required. The aim of this paper is to comparatively assess and validat ...

BioMed Central2023

Accurate Diagnosis of Cortical and Infratentorial Lesions in Multiple Sclerosis Using Accelerated Fluid and White Matter Suppression Imaging

Tobias Kober

Objectives: The precise location of multiple sclerosis (MS) cortical lesions can be very challenging at 3 T, yet distinguishing them from subcortical lesions is essential for the diagnosis and prognosis of the disease. Compressed sensing-accelerated fluid ...

LIPPINCOTT WILLIAMS & WILKINS2023

Unramified F-divided objects and the etale fundamental pro-groupoid in positive characteristic

Giulio Orecchia

Let X /S be a flat algebraic stack of finite presentation. We define a new & eacute;tale fundamental pro-groupoid pi(1)(X /S), generalizing Grothendieck's enlarged & eacute;tale fundamental group from SGA 3 to the relative situation. When S is of equal pos ...

GEOMETRY & TOPOLOGY PUBLICATIONS2022

On the Kawamata-Viehweg vanishing theorem for log del Pezzo surfaces in positive characteristic

Emelie Kerstin Arvidsson, Fabio Bernasconi

We prove the Kawamata-Viehweg vanishing theorem for surfaces of del Pezzo type over perfect fields of positive characteristic p > 5. As a consequence, we show that klt threefold singularities over a perfect base field of characteristic p > 5 are rational. ...

CAMBRIDGE UNIV PRESS2022

Evaluation and optimization of novel extraction algorithms for the automatic detection of atrial activations recorded within the pulmonary veins during atrial fibrillation

Jean-Marc Vesin, Etienne Pruvot, Sasan Yazdani, Adrian Luca, Yann Prudat

Background and objective The automated detection of atrial activations (AAs) recorded from intracardiac electrograms (IEGMs) during atrial fibrillation (AF) is challenging considering their various amplitudes, morphologies and cycle length. Activation time ...

BMC2022

Smart pooling: AI-powered COVID-19 informative group testing

Jorge Andres Madrid Wolff

Massive molecular testing for COVID-19 has been pointed out as fundamental to moderate the spread of the pandemic. Pooling methods can enhance testing efficiency, but they are viable only at low incidences of the disease. We propose Smart Pooling, a machin ...

Nature Portfolio2022

Optimizing the mitigation of epidemic spreading through targeted adoption of contact tracing apps

Andrea Santoro

The ongoing COVID-19 pandemic is the first epidemic in human history in which digital contact tracing has been deployed at a global scale. Tracking and quarantining all the contacts of individuals who test positive for a virus can help slow down an epidemi ...

AMER PHYSICAL SOC2022

Wastewater monitoring outperforms case numbers as a tool to track COVID-19 incidence dynamics when test positivity rates are high

Tamar Kohn, Timothy R. Julian, Joseph Chadi Benoit Lemaitre, Xavier Fernandez Cassi, Alex Tunas Corzon, Federica Cariti

Wastewater-based epidemiology (WBE) has been shown to coincide with, or anticipate, confirmed COVID-19 case numbers. During periods with high test positivity rates, however, case numbers may be underreported, whereas wastewater does not suffer from this li ...

2021

Multiple testing with test statistics following heavy-tailed distributions

Zhiwen Jiang

In multiple testing problems where the components come from a mixture model of noise and true effect, we seek to first test for the existence of the non-zero components, and then identify the true alternatives under a fixed significance level

\alpha

. Two ...

EPFL2021

Using footstep-induced vibrations for occupant detection and recognition in buildings

Ian Smith, Yves Sylvain Gilles Reuland, Sai Ganesh Sarvotham Pai, Slah Drira

Occupant detection and recognition support functional goals such as security, healthcare, and energy management in buildings. Typical sensing approaches, such as smartphones and cameras, undermine the privacy of building occupants and inherently affect the ...

2021

FANOK: Knockoffs in Linear Time

Quentin Rebjock

We describe a series of algorithms that efficiently implement Gaussian model-X knockoffs to control the false discovery rate on large-scale feature selection problems. Identifying the knockoff distribution requires solving a large-scale semidefinite progra ...

SIAM PUBLICATIONS2021

Large variation in anti-SARS-CoV-2 antibody prevalence among essential workers in Geneva, Switzerland

Didier Trono, Idris Guessous, Francisco Javier Perez Saez, Francesco Pennacchio

Limited data exist on SARS-CoV-2 infection rates across sectors and occupations, hindering our ability to make rational policy, including vaccination prioritization, to protect workers and limit SARS-CoV-2 spread. Here, we present results from our SEROCoV- ...

Nature Research2021

On the cortical connectivity in the macaque brain: A comparison of diffusion tractography and histological tracing data

Jean-Philippe Thiran, Gabriel Girard, Maxime Descoteaux, Giorgio Innocenti

Diffusion-weighted magnetic resonance imaging (DW-MRI) tractography is a non-invasive tool to probe neural connections and the structure of the white matter. It has been applied successfully in studies of neurological disorders and normal connectivity. Rec ...

2020

Multiple sclerosis cortical and WM lesion segmentation at 3T MRI: a deep learning method based on FLAIR and MP2RAGE

Jean-Philippe Thiran, Meritxell Bach Cuadra, Cristina Granziera, Muhamed Barakovic, Francesco La Rosa

The presence of cortical lesions in multiple sclerosis patients has emerged as an important biomarker of the disease. They appear in the earliest stages of the illness and have been shown to correlate with the severity of clinical symptoms. However, cortic ...

2020

Longitudinal analysis of white matter and cortical lesions in multiple sclerosis

Tobias Kober, Meritxell Bach Cuadra, Cristina Granziera

Purpose: The goals of this study were to assess the performance of a novel lesion segmentation tool for longitudinal analyses, as well as to validate the generated lesion progression map between two time points using conventional and non-conventional MR se ...

2019

On the intrahemispheric connectivity of the monkey: a diffusion tractography and tract tracing analysis

Gabriel Girard, Maxime Descoteaux, Giorgio Innocenti

In this work, we compare diffusion tractography with neuronal retrograde tract tracing of the frontal, cingulate and parietal areas of the monkey. In this work, we compare diffusion tractography with neuronal retrograde tract tracing of the frontal, cingul ...

International Society for Magnetic Resonance in Medicine2019

Occupant- detection strategy using footstep-induced floor vibrations

Ian Smith, Yves Sylvain Gilles Reuland, Sai Ganesh Sarvotham Pai, Slah Drira

Identification of occupant presence and location inside buildings is essential to functional goals such as security, healthcare, and energy management. Floor-vibration measurements, induced by footstep impacts, provide a non-intrusive sensing method for oc ...

ACM2019

Image-Based Marker-Free Screening of GABA(A) Agonists, Antagonists, and Modulators

Pierre Marquet, Gerardo Turcatti, Benjamin Rappaz, Pascal Jourdain, Fabien Kuttler, Damiano Banfi

The ionotropic GABA(A) receptors represent the main target for different groups of widely used drugs having hypnotic and anxiolytic effects. So far, most approaches used to assess GABA activity involve invasive low -throughput electrophysiological techniqu ...

2019