Rational Design of an Organometallic Glutathione Transferase Inhibitor

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Four arene osmium complexes were prepared containing derivatives of ethacrynic acid, a potent inhibitor of glutathione Stransferases, either by direct coordination or via N- or P-donor ligands. The complexes were characterized by spectroscopic and analytic ...

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Rational Design of an Organometallic Glutathione Transferase Inhibitor

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Phage selection of peptide macrocycles against b-catenin to interfere with Wnt signaling

Development of potent and selective S. aureus sortase A inhibitors Based on Peptide Macrocycles

Arene Osmium Complexes with Ethacrynic Acid-Modified Ligands: Synthesis, Characterization, and Evaluation of Intracellular Glutathione S-Transferase Inhibition and Antiproliferative Activity

Mimicking Enzymatic Active Sites on Surfaces for Energy Conversion Chemistry

Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor

How Structural and Physicochemical Determinants Shape Sequence Constraints in a Functional Enzyme

Phage Selection of Bicyclic Peptides and High-Throughput Screening of Chemical Compounds for the Identification of Novel Inhibitors of the Notch Pathway

Reconstitution of [Fe]-hydrogenase using model complexes

Diminazene Protects Corpus Cavernosum Against Hypercholesterolemia-Induced Injury