Cholesterol Hinders the Passive Uptake of Amphiphilic Nanoparticles into Fluid Lipid Membranes

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Bioaccumulation is defined as the enrichment of a compound in an organism relative to the surrounding water or its food, and is an important endpoint in chemical risk assessment. Under laboratory conditions, bioaccumulation is measured as bioconcentration ...

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A key player in the formation of endoplasmic reticulum sheets is CLIMP-63, but mechanistic details remained elusive. Here authors combined cellular experiments and mathematical modelling to show that S-acylation of CLIMP-63 regulates its function by mediat ...

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Serial crystallography at X-ray free-electron lasers (XFELs) permits the determination of radiation-damage free static as well as time-resolved protein structures at room temperature. Efficient sample delivery is a key factor for such experiments. Here, we ...

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Studying the role of molecularly distinct lipid species in cell signaling remains challenging due to a scarcity of methods for performing quantitative lipid biochemistry in living cells. We have recently used lipid uncaging to quantify lipid -pro-tein affi ...

Dysregulations in cholesterol metabolism are associated with neurodegenerative and vascular pathologies, and dementia. Diet-derived plant sterols (phytosterols) have cholesterol-lowering, anti-inflammatory, and antioxidant properties and may interfere with ...

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Cholesterol Hinders the Passive Uptake of Amphiphilic Nanoparticles into Fluid Lipid Membranes

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The Bioaccumulation of Ionizable Organic Compounds in Fish Cell Lines

Time-Resolved Scanning Ion Conductance Microscopy and Single-Molecule Spectroscopy

Dynamics of CLIMP-63 S-acylation control ER morphology

MPD and TMC supply as parameters to describe synthesis-morphology-performance relationships of polyamide thin film composite membranes

Urtica dioica Leaf Infusion Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Cisplatin Treatment

Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase

A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers

Information Theory in Transmembrane Transport

Selectively permeable microcapsules

Quantifying single-cell diacylglycerol signaling kinetics after uncaging

Plant sterols and cholesterol metabolism are associated with five-year cognitive decline in the elderly population

Towards ultrathin metal-organic frameworks membranes for high-performance separation