Publications related to Inertial microfluidic programming of microparticle-laden flows for solution transfer around cells and particles

Related publications (29)

Noise-induced transitions past the onset of a steady symmetry-breaking bifurcation: The case of the sudden expansion

François Gallaire, Edouard Boujo, Yves-Marie François Ducimetière

We consider fluid flows, governed by the Navier-Stokes equations, subject to a steady symmetry-breaking bifurcation and forced by a weak noise acting on a slow timescale. By generalizing the multiple-scale weakly nonlinear expansion technique employed in t ...

2024

Rapid motion estimation and correction using self-encoded FID navigators in 3D radial MRI

Tobias Kober, Davide Piccini

Purpose: To develop a self-navigated motion compensation strategy for 3D radial MRI that can compensate for continuous head motion by measuring rigid body motion parameters with high temporal resolution from the central k-space acquisition point (self-enco ...

Wiley2023

lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications

Alfio Quarteroni, Luca Dede'

Computational fluid dynamics (CFD) is an important tool for the simulation of the cardiovascular function and dysfunction. Due to the complexity of the anatomy, the transitional regime of blood flow in the heart, and the strong mutual influence between the ...

Elsevier2023

Acoustofluidic large-scale mixing for enhanced microfluidic immunostaining for tissue diagnostics

Martinus Adela Maria Gijs, Diego Gabriel Dupouy, Muaz Salama Abdelmonem Draz

The usage of microfluidics for automated and fast immunoassays has gained a lot of interest in the last decades. This integration comes with certain challenges, like the reconciliation of laminar flow patterns of micro-scale systems with diffusion-limited ...

ROYAL SOC CHEMISTRY2023

Microfluidic device combining hydrodynamic and dielectrophoretic trapping for the controlled contact between single micro-sized objects and application to adhesion assays

Philippe Renaud, Arnaud Bertsch, Clémentine Sophie Sarah Lipp

The understanding of cell-cell and cell-matrix interactions via receptor and ligand binding relies on our ability to study the very first events of their contact. Of particular interest is the interaction between a T cell receptor and its cognate peptide-m ...

ROYAL SOC CHEMISTRY2023

Numerical study on the scale effect of tip vortex cavitation induced by incoming velocities and scale ratios

Mohamed Farhat

Large eddy simulations of tip vortex cavitation (TVC) around an elliptical hydrofoil is performed to study its scale effect. A satisfying agreement is obtained between the numerical and experimental data. It indicates that the scale effect of TVC is remark ...

PERGAMON-ELSEVIER SCIENCE LTD2023

A Fast Hybrid Pressure-Correction Algorithm for Simulating Incompressible Flows by Projection Methods

Jiannong Fang

To enforce the conservation of mass principle, a pressure Poisson equation arises in the numerical solution of incompressible fluid flow using the pressure-based segregated algorithms such as projection methods. For unsteady flows, the pressure Poisson equ ...

2023

Weakly nonlinear versus semi-linear models of the nonlinear evolution of the centrifugal instability

François Gallaire, Eunok Yim

We carry out a weakly nonlinear analysis of the centrifugal instability for a columnar vortex in a rotating fluid, and compare the results to those of the semi-linear model derived empirically by Yim et al. (J. Fluid Mech., vol. 897, 2020, A34). The asympt ...

Cambridge University Press2023

Anomalous Dissipation and Lack of Selection in the Obukhov-Corrsin Theory of Scalar Turbulence

Maria Colombo, Massimo Sorella

The Obukhov-Corrsin theory of scalar turbulence [21, 54] advances quantitative predictions on passive-scalar advection in a turbulent regime and can be regarded as the analogue for passive scalars of Kolmogorov's K41 theory of fully developed turbulence [4 ...

Springernature2023

On the Capability of Wall-Modeled Large Eddy Simulations to Predict Particle Dispersion in Complex Turbulent Flows

Mohamed Aly Hashem Mohamed Sayed

Predicting particle transport in turbulent flows has a plethora of applications, some of which are: the transport of atmospheric aerosols, the deposition of blood cells in the arteries of human bodies and the atomization of fuel droplets in combustion cham ...

EPFL2022

Experimental and numerical investigation of the unbalance behavior of rigid rotors supported by spiral-grooved gas journal bearings

Jürg Alexander Schiffmann, Elia Iseli

The forced response of rigid rotors, supported by herringbone-grooved gas journal bearings are investigated numerically and experimentally. The rotor configurations are varied by using end cylinders, attached at both sides of the shaft. Three rotors with d ...

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD2022

From coating flow patterns to porous body wake dynamics via multiscale models

Pier Giuseppe Ledda

Multiscale phenomena are involved in countless problems in fluid mechanics. Coating flows are known to exhibit a broad variety of patterns, such as wine tears in a glass and dripping of fresh paint applied on a wall. Coating flows are typically modeled und ...

EPFL2022

Data-Driven Reduced-Order Modeling of Convective Heat Transfer in Porous Media

Carlo Fiorina

This work presents a data-driven Reduced-Order Model (ROM) for parametric convective heat transfer problems in porous media. The intrusive Proper Orthogonal Decomposition aided Reduced-Basis (POD-RB) technique is employed to reduce the porous medium formul ...

MDPI2021

Buoyancy-driven convection of droplets on hot nonwetting surfaces

François Gallaire, Eunok Yim

The global linear stability of a water drop on hot nonwetting surfaces is studied. The droplet is assumed to have a static shape and the surface tension gradient is neglected. First, the nonlinear steady Boussinesq equation is solved to obtain the axisymme ...

AMER PHYSICAL SOC2021

Microfluidics and cell-free synthetic biology in the development of new diagnostic and therapeutic platforms

Grégoire Michielin

In phenylketonuria, absence or malfunction of the phenylalanine hydroxylase enzyme results in toxic accumulation of phenylalanine in the body. An injectable recombinant enzyme therapy was recently approved and has the potential to improve the quality of li ...

EPFL2021

Evolution of the vorticity distribution in vortex rings

Guillaume de Guyon-Crozier

Vortex rings are very efficient at transporting fluid on long distances and can generate large forces, either thrust or drag. These abilities are influenced by the vorticity distribution within the vortex. Previous work on vortices produced by piston-cylin ...

EPFL2021

Stability and Unbalance Analysis of Rigid Rotors Supported by Spiral Groove Bearings: Comparison of Different Approaches

Jürg Alexander Schiffmann, Elia Iseli

The dynamic behavior of spiral-grooved gas bearing supported four degrees-of-freedom (DOF) rotors is investigated by means of linearized bearing force coefficients and full time-integrated transient analysis. The transient method consists of a state-space ...

2021

Cell penetration efficiency analysis of different atomic force microscopy nanoneedles into living cells

Marcos Penedo Garcia

Over the last decade, nanoneedle-based systems have demonstrated to be extremely useful in cell biology. They can be used as nanotools for drug delivery, biosensing or biomolecular recognition inside cells; or they can be employed to select and sort in par ...

Nature Research2021

Microfluidic culture platforms for C. elegans bacterial interaction and digestion studies at single-organism resolution

Vittorio Viri

Increasing interest in understanding fundamental biological processes, among which aging and nutrition, has led to the study of simple and powerful model organisms, as the round-worm Caenorhabditis elegans (C. elegans). The nematode, selected by Sydney Bre ...

EPFL2021

Fundamental study on microlayer dynamics in nucleate boiling

Lubomír Bures

Dynamics of nucleate boiling are strongly affected by the formation and behaviour of the microlayer, a layer of liquid underneath growing bubbles. As a result of its minute thickness, very high heat fluxes occur within the microlayer and its evaporation co ...

EPFL2021