Publication

Enzymatic hydrolysis of organic-core microcapsules to produce aqueous-core microcapsules

Related publications (25)

Optimality principles for the analysis of biological processes across scales: From enzyme kinetics to microbiome dynamics

Microorganisms are essential for life on Earth, performing key roles in numerous biological processes. Their influence extends across a wide spectrum, from human health and ecological balance to advancements in biotechnology and industrial applications. Th ...

EPFL2024

An explainability framework for deep learning on chemical reactions exemplified by enzyme-catalysed reaction classification

Daniel Probst

Assigning or proposing a catalysing enzyme given a chemical or biochemical reaction is of great interest to life sciences and chemistry alike. The exploration and design of metabolic pathways and the challenge of finding more sustainable enzyme-catalysed a ...

2023

Model-based scale-up of a continuously operated consolidated bioprocess based on a microbial consortium for the production of ethanol

David Beat Dempfle

This work demonstrated that consolidated bioprocessing is a promising concept for conversion of lignocellulose to ethanol at industrial scale. CBP offers great cost saving potential, is feasible to be operated continuously and may be scaled up due to exten ...

EPFL2022

Dissecting the role of the asparagine synthesis in acute liver injury

Yu Sun

Amino acids are some of the main building stones of life used in a variety of biological processes, such as protein synthesis, energy metabolism or even as precursors for hormone synthesis. How-ever, some of them also participate and coordinate certain cel ...

EPFL2022

Adsorption of organic matter on titanium surfaces with nano- and micro-scale roughness studied with the electrochemical quartz crystal microbalance dissipation technique

Stefano Mischler, Anna Neus Igual Muñoz

Adsorption of calf serum organic matter from a phosphate-buffered solution was studied using the electrochemical quartz crystal microbalance with additional dissipation measurements. Two types of crystal surfaces were used: one rough with micrometer-range ...

AIP Publishing2021

Hetero-Bis-Conjugation of Bioactive Molecules to Half-Sandwich Ruthenium(II) and Iridium(III) Complexes Provides Synergic Effects in Cancer Cell Cytotoxicity

Paul Joseph Dyson, Lucinda Kate Batchelor, Mouna Hadiji

Four bipyridine-type ligands variably derivatized with two bioactive groups (taken from ethacrynic acid, flurbiprofen, biotin, and benzylpenicillin) were prepared via sequential esterification steps from commercial 2,2'-bipyridine-4,4'-dicarboxylic acid an ...

AMER CHEMICAL SOC2021

Organohalide respiration in Firmicutes: energy metabolism and transcription regulation

Mathilde Stéphanie Willemin

Organohalides are a class of compounds often considered as persistent pollutants and harmful to environmental and human health. Some bacteria, among which are representatives from the Firmicutes phylum, are capable of using these compounds as terminal acce ...

EPFL2021

Modeling, predicting and mining metabolism at atom-level resolution

Jasmin Maria Hafner

Living organisms can catalyze many thousands of biochemical reactions that they use to convert energy and matter, which provides them with the essentials for life. The sum of these chemical reactions happening in an organism is called metabo-lism. Understa ...

EPFL2020

Method and system for analysis of organic material by auto-cathodoluminescence

Hans Mattias Larsson, Marcin Stefan Zielinski

Analyzing isolated collagen gel samples of a rat-tail and bovine hide, we demonstrated in situ detection of spectrally deconvoluted auto-cathodoluminescence signatures of specific molecular content with precise spatial localization over a maximum field of ...

2020

Evaluation of the NAD(+) biosynthetic pathway in ALS patients and effect of modulating NAD(+) levels in hSOD1-linked ALS mouse models

Johan Auwerx

Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of motor neurons. Astrocytes from diverse ALS models induce motor neuron death in co-culture. Enhancing NAD(+) availability, or increasing the expression of the NAD(+)-depende ...

2020

Molecular engineering of functional materials for optoelectronic applications

Nikita Drigo

Organic functional materials are indispensable components for the last generation of light-energy conversion devices. Photo- and electroactive small organic molecules constitute thin active (emitting, transporting, blocking, injecting etc.) layers of organ ...

EPFL2020

Nano-sized iron oxides supported on polyester textile to remove fluoroquinolones in hospital wastewater

Sami Rtimi

In this study, we examined the removal kinetics of two fluoroquinolones (FQs), flumequine (FLU) and ciprofloxacin (CIP), in synthetic wastewater (SWW) and real hospital wastewater (RHW) using FeOx thin films, peroxymonosulfate (PMS) and visible light. Nano ...

ROYAL SOC CHEMISTRY2020

Hydrogen-Bonded Small Molecules and Polymers in Organic Electronics

Bilal Özen

Organic semiconductors are important components for applications in different fields of technology, as their advantages include the possibility of low-temperature processing as well as low-cost, large-area manufacturing based on solution-based processes, c ...

EPFL2020

Photovoltaic organic interface for neuronal stimulation in the near-infrared

Naïg Aurelia Ludmilla Chenais, Marta Jole Ildelfonsa Airaghi Leccardi, Diego Ghezzi, Laura Ferlauto, Elodie Geneviève Zollinger

Organic materials, such as conjugated polymers, are attractive building blocks for bioelectronic interfaces. In particular, organic semiconductors show excellent performance in light-mediated excitation and silencing of neuronal cells and tissues. However, ...

2020

Enzyme annotation for orphan and novel reactions using knowledge of substrate reactive sites

Ljubisa Miskovic, Vassily Hatzimanikatis, Noushin Hadadi, Marianne Seijo

Thousands of biochemical reactions with characterized activities are “orphan,” meaning they cannot be assigned to a specific enzyme, leaving gaps in metabolic pathways. Novel reactions predicted by pathway-generation tools also lack associated sequences, l ...

National Academy of Sciences2019

Particle-Based Simulation Reveals Macromolecular Crowding Effects on the Michaelis-Menten Mechanism

Vassily Hatzimanikatis, Daniel Robert Weilandt

Many computational models for analyzing and predicting cell physiology rely on in vitro data collected in dilute and controlled buffer solutions. However, this can mislead models because up to 40% of the intracellular volume-depending on the organism, the ...

2019

Seasonality alters drivers of soil enzyme activity in subalpine grassland soil undergoing climate change

Alexandre Buttler, Thomas Spiegelberger, Konstantin Svetlozarov Gavazov, Robert Thomas Edmund Mills, Vincent Eric Jules Jassey, Bjorn Jozef Maria Robroek

In mountain ecosystems with marked seasonality, climate change can affect various processes in soils, potentially modifying long-term key soil services via change in soil organic carbon (C) storage. Based on a four-year soil transplantation experiment in S ...

PERGAMON-ELSEVIER SCIENCE LTD2018

Heterotetracenes: Flexible Synthesis and in Silico Assessment of the Hole Transport Properties

Kevin Sivula, Anne-Clémence Corminboeuf, Jérôme Waser, Xavier Adrian Jeanbourquin, Yifan Li, Felipe Andres Saenz Padilla, Ganna Gryn'ova

Thienoacenes and furoacenes are among the most frequent molecular units found in organic materials. The efficient synthesis of morphologically different heteroacenes and the rapid determination of their solid-state and electronic properties are still chall ...

2017

Land use controls stream ecosystem metabolism by shifting dissolved organic matter and nutrient regimes

Amber Joy Ulseth

Stream ecosystem metabolism integrates production and respiration of organic matter and plays a fundamental role in the global carbon (C) cycle. Several studies have identified distal and proximal physical controls, for example, land use and transient s ...

Wiley-Blackwell2017

Demonstration and Characterization of Ladder-Type Conjugated Polymer Photoanode for Direct Light-Driven Water Oxidation

Pauline Bornoz

Energy production is not only a scientific challenge. It also has implications on human and animal health, global environment, and international politics and economics. In order to reduce these effects, the development of a new clean and renewable method i ...

EPFL2017