Publications related to PET REBINNING WITH REGULARIZED DENSITY SPLINES

Related publications (34)

Machine learning enhanced tomographic reconstruction for multispectral imaging on TCV

A multispectral camera setup is used to infer a 2D map of plasma parameters in a tokamak from spectral emissions. However, the light measured by these cameras is line integrated in the toroidal direction, whereas emissivities on the poloidal plane are nece ...

2025

Integrated electronics for time-of-flight positron emission tomography photodetectors

Andrada Alexandra Muntean

Positron emission tomography is a nuclear imaging technique well known for its use in oncology for cancer diagnosis and staging. A PET scanner is a complex machine which comprises photodetectors placed in a ring configuration that detect gamma photons gen ...

EPFL2023

Correlated-photon imaging at 10 volumetric images per second

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü, Paul Mos

The correlation properties of light provide an outstanding tool to overcome the limitations of traditional imaging techniques. A relevant case is represented by correlation plenoptic imaging (CPI), a quantum-inspired volumetric imaging protocol employing s ...

Nature Portfolio2023

Down-conversion of a single photon as a probe of many-body localization

Cristiano Ciuti

Decay of a particle into more particles is a ubiquitous phenomenon to interacting quantum systems, taking place in colliders, nuclear reactors or solids. In a nonlinear medium, even a single photon would decay by down-converting (splitting) into lower-freq ...

NATURE PORTFOLIO2023

Medipix4, a high granularity four sides buttable pixel readout chip for high resolution spectroscopic X-ray imaging at rates compatible with medical CT scans

Viros Sriskaran

Medipix4 is the latest member in the Medipix/Timepix family of pixel detector chips aimed at high rate spectroscopic X-ray imaging using high-Z materials. The chip address the limitations of conventional hybrid pixel detectors for X-ray imaging. Its predec ...

EPFL2022

Bragg edge tomography characterization of additively manufactured 316L steel

Roland Logé, Christian Leinenbach, Nikola Kalentics

In this work we perform a neutron Bragg edge tomography of stainless steel 316L additive manufacturing samples, one as built via standard laser powder bed fusion, and one using the novel three-dimensional (3D) laser shock peening technique. First, we consi ...

AMER PHYSICAL SOC2022

Recent results with radiation-tolerant TowerJazz 180 nm MALTA sensors

Francesco Piro

To achieve the physics goals of future colliders, it is necessary to develop novel, radiation-hard silicon sensors for their tracking detectors. We target the replacement of hybrid pixel detectors with Depleted Monolithic Active Pixel Sensors (DMAPS) that ...

ELSEVIER2022

High-Performance CMOS SPAD-Based Sensors for Time-of-Flight PET Applications

Francesco Gramuglia

Detecting light, photon by photon, has been possible since the 1930s, with the invention of the photomultiplier tube (PMT). However, it is only since the 1970s, that solid-state single-photon detectors have emerged and only since 2003 that a new technology ...

EPFL2022

Method and light microscope with a plurality of arrays of photon-counting detector elements

Edoardo Charbon, Claudio Bruschini, Ivan Michel Antolovic

A method for operating a light microscope comprises emitting and guiding a plurality of illumination light beams towards a specimen (6) to form a plurality of separated illumination light spots (2A, 2B, 2C, 2D) at the specimen; and guiding detection light ...

2022

Pixel super-resolution with spatially entangled photons

Edoardo Charbon, Jiuxuan Zhao

Pixelation is common in quantum imaging systems and limit the image spatial resolution. Here, the authors introduce a pixel super-resolution approach based on measuring the full spatially-resolved joint probability distribution of spatially-entangled photo ...

Nature Portfolio2022

Data-driven myelin water imaging based on T-1 and T-2 relaxometry

Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Marco Pizzolato

Long acquisition times preclude the application of multiecho spin echo (MESE) sequences for myelin water fraction (MWF) mapping in daily clinical practice. In search of alternative methods, previous studies of interest explored the biophysical modeling of ...

WILEY2021

Large-Format Time-Gated SPAD Cameras for Real-Time Phasor-Based FLIM

Arin Can Ülkü

Fluorescence lifetime imaging microscopy (FLIM) is an imaging modality often used to monitor biochemical properties of a cell or a tissue. In addition to conventional fluorescence microscopy features, such as selective labeling and non-invasiveness, FLIM e ...

EPFL2021

Revisiting the T-2 spectrum imaging inverse problem: Bayesian regularized non-negative least squares

Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Multi-echo T-2 magnetic resonance images contain information about the distribution of T-2 relaxation times of compartmentalized water, from which we can estimate relevant brain tissue properties such as the myelin water fraction (MWF). Regularized non-neg ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2021

n-photon blockade with an n-photon parametric drive

Fabrizio Minganti

We propose a mechanism to engineer an n-photon blockade in a nonlinear cavity with an n-photon parametric drive lambda(adagger n + an). When an n-photon-excitation resonance condition is satisfied, the presence of n photons in the cavity suppress ...

AMER PHYSICAL SOC2021

Roadmap toward the 10 ps time-of-flight PET challenge

Edoardo Charbon, Mathieu Benoit

Since the seventies, positron emission tomography (PET) has become an invaluable medical molecular imaging modality with an unprecedented sensitivity at the picomolar level, especially for cancer diagnosis and the monitoring of its response to therapy. Mor ...

IOP PUBLISHING LTD2020

Model-informed machine learning for multi-component T2 relaxometry

Jean-Philippe Thiran, Tobias Kober, Meritxell Bach Cuadra, Tom Hilbert, Erick Jorge Canales Rodriguez, Cristina Granziera, Muhamed Barakovic, Marco Pizzolato, Elda Fischi Gomez, Thomas Yu, Gian Franco Piredda

Recovering the distribution from multi-echo magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this work, we propose to comb ...

2020

Methods and apparatus for tomographic additive manufacturing with a spatially coherent light source

Christophe Moser, Damien Claude-Marie Loterie, Paul Delrot

A method of fabricating a three-dimensional article comprises providing a spatially coherent light source (101, 201), generating from said light source (101, 201), patterns of light based on computed tomographic projections of said three-dimensional articl ...

2020

Toward Bright and Pure Single Photon Emitters at 300 K Based on GaN Quantum Dots on Silicon

Nicolas Grandjean, Raphaël Butté, Gordon Jens Callsen, Sebastian Pascal Tamariz Kaufmann, Johann Nicolaï Stachurski, Kanako Shojiki

Quantum dots (QDs) based on III-nitride semi-conductors are promising for single photon emission at noncryogenic temperatures due to their large exciton binding energies. Here, we demonstrate GaN QD single photon emitters operating at 300 K with g((2)) (0) ...

AMER CHEMICAL SOC2020

Quanta burst photography

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü

Single-photon avalanche diodes (SPADs) are an emerging sensor technology capable of detecting individual incident photons, and capturing their time-of-arrival with high timing precision. While these sensors were limited to singlepixel or low-resolution dev ...

Association for Computing Machinery (ACM)2020

Neural network training for cross-protocol radiomic feature standardization in computed tomography

Adrien Raphaël Depeursinge

Radiomics has shown promising results in several medical studies, yet it suffers from a limited discrimination and informative capability as well as a high variation and correlation with the tomographic scanner types, pixel spacing, acquisition protocol, a ...

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS2019