CDK4 Phosphorylates AMPK alpha 2 to Inhibit Its Activity and Repress Fatty Acid Oxidation

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Over the past two decades, protein S-acylation (often referred to as S-palmitoylation) has emerged as an important regulator of vital signalling pathways. S-Acylation is a reversible post-translational modification that involves the attachment of a fatty a ...

Communication between the intestine and other organs such as the lungs, brain or bones is mediated by several metabolites, like short-chain fatty acids or bile acids, that relay information about nutritional and microbiota status. Bile acids are endogenous ...

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High-grade gliomas (HGG) are the most common and most aggressive primary tumors of the brain. Despite recent advances in neuro-oncology survival of these tumors remains around 12-15 months. The first-line of treatment is surgical resection. However, due to ...

Curcuminoids and their complexes continue to attract attention in medicinal chemistry, but little attention has been given to their metabolic derivatives. Here, the first examples of (arene)Ru(II) complexes with curcuminoid metabolites, tetrahydrocurcumin ...

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CDK4 Phosphorylates AMPK alpha 2 to Inhibit Its Activity and Repress Fatty Acid Oxidation

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Mechanisms and functions of protein S-acylation

Characterization of the gut-bone marrow axis through bile acid signaling

In situ architecture of Opa1-dependent mitochondrial cristae remodeling

Cyclo His-Pro Attenuates Muscle Degeneration in Murine Myopathy Models

Evaluation of antigravitational support levels provided by a passive upper-limb occupational exoskeleton in repetitive arm movements

Deciphering the nature of cell state transitions in single cells using quantitative modeling of temporal dynamics

Fluorescent fatty acid conjugates for live cell imaging of peroxisomes

A fatty-acid based probe for near-infrared fluorescence guided surgery of glioblastoma

Ru(II)-Arene Complexes of Curcumin and Bisdesmethoxycurcumin Metabolites

Clinically compliant cryopreservation of differentiated retinal pigment epithelial cells

Mitophagy Activation by Urolithin A to Target Muscle Aging

Proteome adaptations of the organohalide-respiring Desulfitobacterium hafniense strain DCB-2 to various energy metabolisms

Modeling, analysis, and design of complex biological networks

Robust gamma-aminobutyric acid and energy metabolism measurements by proton and phosphorus magnetic resonance spectroscopy and fingerprinting

Metabolic dependencies of metastasis-initiating cells in female breast cancer

Engineering extracellular electron transfer for enhanced energy harvesting in microbial electrochemical devices

NAD(+) Metabolism and Interventions in Premature Renal Aging and Chronic Kidney Disease

Genomics of Preaxostyla Flagellates Illuminates the Path Towards the Loss of Mitochondria

Countering T cell exhaustion and senescence for enhanced adoptive T cell therapies against solid tumors

Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging