Integrated Nanophotonic Biosensors for Point-of Care Diagnostics and Bioanalytical Applications

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Critical review of standards for indoor thermal environment and air quality

Dolaana Khovalyg

Quality of the indoor environment has become an important parameter to account for in new and existing buildings due to the increasing number of people spending most of their time indoors. Generally, the design and evaluation of indoor environments in buil ...

2020

Microfluidic staining technology and automated image processing for fast and accurate tissue-based diagnostics

Diego Gabriel Dupouy

The development of microfluidics has led to significant improvements in many areas of in vitro diagnostics. This thesis proposes the use of microfluidic device technology in the field of anatomic pathology, leading to faster and more accurate tissue-based ...

EPFL2016

Piégeage optique résonant et analyse du mouvement de nanoparticules piégées dans des cristaux photoniques à cavités creuses

Mario Lucien Henri Tonin

Optical trapping was used for decades in biotechnology for a broad range of applications. It can be used for remote manipulation, application of pico-Newton forces and even study DNA processes. Nevertheless, optical trapping setups can be cumbersome. In or ...

EPFL2016

Chlorothalonil transformation products in drinking water resources: Widespread and challenging to abate

Urs von Gunten

Chlorothalonil, a fungicide applied for decades worldwide, has recently been banned in the European Union (EU) and Switzerland due to its carcinogenicity and the presence of potentially toxic transformation products (TPs) in groundwater. The spread and con ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Continuous quantification of HER2 expression by microfluidic precision immunofluorescence estimates HER2 gene amplification in breast cancer

Martinus Adela Maria Gijs, Ata Tuna Ciftlik, Diego Gabriel Dupouy

Chromogenic immunohistochemistry (IHC) is omnipresent in cancer diagnosis, but has also been criticized for its technical limit in quantifying the level of protein expression on tissue sections, thus potentially masking clinically relevant data. Shifting f ...

Nature Research2016

Microfluidic systems for cancer diagnostics

Sebastian Maerkl

Although not employed in the clinic as of yet, microfluidic systems are likely to become a key technology for cancer diagnostics and prognosis. Microfluidic devices have been developed for the analysis of various biomarkers including circulating tumor cell ...

2020

Merging microfluidics and micro-array concepts: from molecular to nematode-based bioassays

Matteo Cornaglia

Essential in biomedical research is the necessity of gathering statistically relevant data about large populations of specific biological entities, e.g. organisms, cells or molecules, while preserving detailed information about each single entity under in ...

EPFL2015

Unsupervised Stereo Matching Using Confidential Correspondence Consistency

Seungryong Kim

Stereo matching aims to perceive the 3D geometric configuration of scenes and facilitates a variety of computer vision in advanced driver assistance systems (ADAS) applications. Recently, deep convolutional neural networks (CNNs) have shown dramatic perfor ...

IEEE Institute of Electrical and Electronics Engineers2020

Band-bending induced passivation: high performance and stable perovskite solar cells using a perhydropoly(silazane) precursor

Mohammad Khaja Nazeeruddin, Mounir Driss Mensi, Valentin Ianis Emmanuel Queloz, Yonghui Lee, Kyung Taek Cho, Sanghyun Paek, Cristina Roldán Carmona, Aron Joel Huckaba, Giulia Grancini, Yi Zhang, Hiroyuki Kanda, Nadja Isabelle Desiree Klipfel, Mo Li

Surface passivation of the perovskite photo absorber is a key factor to improve the photovoltaic performance. So far robust passivation strategies have not yet been revealed. Here, we demonstrate a successful passivation strategy which controls the Fermi-l ...

2020

Ultra-rapid prototyping of flexible, multi-layered microfluidic devices via razor writing

Matthias Lütolf, Steffen Cosson, Nathalie Brandenberg

The fabrication of microfluidic devices is often still a time-consuming and costly process. Here we introduce a very simple and cheap microfabrication process based on "razor writing", also termed xurography, for the ultra-rapid prototyping of microfluidic ...

Royal Soc Chemistry2015

Microfluidic Scintillation Detectors for High Energy Physics

Pietro Maoddi

This thesis deals with the development and study of microfluidic scintillation detectors, a technology of recent introduction for the detection of high energy particles. Most of the interest for such devices comes from the use of a liquid scintillator, whi ...

EPFL2015

Estimation of regional trip length distributions for the calibration of the aggregated network traffic models

Nikolaos Geroliminis

The calibration of trip lengths is an important challenge for multi-regional MFD-based applications, as it can influence the dynamics of regional densities (and speeds). Existing research has not paid significant attention in the topic, giving opportunitie ...

2019