Biomimetic materials in tissue engineering

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Hydrogels have emerged as promising materials for bioelectronic interfaces due to their tissue-like properties and high-water content. However, conventional hydrogels often suffer from poor electrical conductivity and mechanical stability, limiting their p ...

Chondrocytes within articular cartilage possess the capacity to perceive and react to signals generated by the typical load-bearing actions of daily life, such as walking or running. Articular cartilage is predominantly oriented toward compression-based fu ...

Transient robots are robots designed to be non-long-lasting and degradable over time. This design philosophy is ideal for a wide range of applications, from environmental monitors to implantable systems. In this commentary, we explore the concept of transi ...

Organoids, miniature tissues generated from self-organizing stem cells within three-dimensional (3D) extracellular matrices (ECM), have opened up exciting possibilities for in vitro studies of complex physiological processes. A key factor in the success of ...

Atomic force microscopy (AFM) is a widely used imaging tool for obtaining a variety of information for a range of samples. Although it was initially intended to serve as a method of observing very flat solid surfaces, its use expanded into several other fi ...

Nature produces soft materials with fascinating combinations of mechanical properties. For example, the mussel byssus embodies a combination of stiffness and toughness, a feature that is unmatched by synthetic hydrogels. Key to enabling these excellent mec ...

Most codes of practice adopt a semi probabilistic design approach for the dimensioning and assessment of structures. Accordingly, structural safety is ensured by performing limit state verifications using design values determined with adequately calibrated ...

When two objects slide against each other, wear and friction occur at their interface. The accumulation of wear forms what is commonly referred to as a ``third-body''. Understanding third-body evolution has significant applications in industry, where contr ...

Supramolecular interactions play an important role in defining the structure and the resulting mechanical properties of materials. For instance, interchain hydrogen-bonding in PAs gives them superior strength and stiffness in engineering materials, while t ...

Dielectric elastomer actuators (DEA) are elastic capacitors composed of a pair of compliant electrodes and a soft dielectric elastomer film sandwiched in between. This kind of stretchable capacitors can be actuated when charged, can generate electricity fr ...

Hydrogels are a class of soft materials, which display unique biomimetic properties to biological tissues. Their mechanical properties, high water content, and porosity resemble that of extracellular matrix so that cell growth and proliferation can be reli ...

Hydrogels are among the first materials expressly designed for their use in biomedicine. However, state-of-the-art applications of hydrogels are severely limited because they are typically either too soft or too brittle such that they cannot bear significa ...

Repairing articular osteochondral defects present considerable challenges in self-repair due to the complex tissue structure and low proliferation of chondrocytes. Conventional clinical therapies have not shown significant efficacy, including microfracture ...

Extracellular vesicles (EVs) are small, lipid-bilayer-bound particles released by cells that can contain important bioactive molecules, including lipids, RNAs, and proteins. Once released in the extracellular environment, EVs can act as messengers locally ...

Conventional formworks for concrete curved shells either are expensive, complex and wasteful or have formal restrictions. Using tile vaults (also known as timbrel, Guastavino, thin-tile or Catalan vaults) as stay-in-place formwork for concrete shells could ...

To address the rising demand for plastics, it is essential to create new types of polymers that are both highly recyclable and emit minimal amounts of greenhouse gases. These plastics should be derived from readily available, renewable feedstocks. Such eff ...

Structural, functional and molecular cardiac defects have been reported in spinal muscular atrophy (SMA) patients and mouse models. Previous quantitative proteomics analyses demonstrated widespread molecular defects in the severe Taiwanese SMA mouse model. ...

In this work a multilayer barrier paperboard was produced in a roll-to-roll process by slot-die coating of nanocellulose (microfibrillated cellulose or carboxymethylated cellulose nanofibrils) followed by extrusion coating of biodegradable thermoplastics ( ...

The physical properties of many modern multi-component materials are determined by their internal microstructure. Tools capable of characterizing complex nanoscale architectures in composite materials are, therefore, essential to design materials with targ ...

The vibrational response of solid materials and structural components is substantially governed by their mechanical and geometrical properties. Low-frequency vibrations and modal frequencies are sensitive to global geometrical deviations, while high-freque ...

Biomimetic materials in tissue engineering

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Direct laser writing of electronically conductive microstructures within soft hydrogel substrates

Enhancing Chondrocyte Biosynthetic Activities: Harnessing the Power of Loading-Induced Evolved Temperature

The rise of transient robotics

Engineering hydrogel microenvironments for epithelial organoid culture

Advancements in Nanomechanical Characterization and Biomolecular Imaging with Atomic force Microscopy

Localized Ionic Reinforcement of Double Network Granular Hydrogels

Influence of model uncertainty and long term deformations in action effects calculation in reinforced concrete structures

Modeling friction and wear using an adaptive discrete-continuum coupling

Supramolecular Modifications of Semicrystalline Polymers

Bottlebrush Dielectric Elastomers with Improved Properties for Actuation

Hydrogels and conductive hydrogels for implantable bioelectronics

Controlling the Microstructure and Composition of 3D Printed Soft Load-Bearing Hydrogels

Bioinspired gradient scaffolds for osteochondral tissue engineering

Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report

Experimental testing and structural analysis of composite tile – reinforced concrete domes

Acetal-Stabilized Carbohydrates as Novel Platform Molecules for Renewable Polymer Production

AAV9-mediated SMN gene therapy rescues cardiac desmin but not lamin A/C and elastin dysregulation in Smn(2B/-) spinal muscular atrophy mice

Tailoring the performance of nanocellulose-based multilayer-barrier paperboard using biodegradable-thermoplastics, pigments, and plasticizers

Imaging Radial Distribution Functions of Complex Particles by Relayed Dynamic Nuclear Polarization

Vibrational NDT with Under-sampled Data through Physics-informed Neural Networks