Publications by Diego Ghezzi | EPFL Graph Search

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Retinal prostheses can restore a functional form of vision in patients affected by dystrophies of the outer retinal layer. Beyond clinical utility, prostheses for the stimulation of the optic nerve, the visual thalamus or the visual cortex could also serve ...

Objective. Temporal resolution is a key challenge in artificial vision. Several prosthetic approaches are limited by the perceptual fading of evoked phosphenes upon repeated stimulation from the same electrode. Therefore, implanted patients are forced to p ...

Bioelectronic and neuroprosthetic interfaces rely on implanted microelectrode arrays (MEAs) to interact with the human body. Printing techniques, such as inkjet and screen printing, are attractive methods for the manufacturing of MEAs because they allow fl ...

Neurotechnology applies methods and devices to mitigate the burden of neurological and mental disorders. In particular, neural interfaces establish a long-term, seamless, symbiotic integration between implants and neural tissue. Materials play a pivotal ro ...

Three-coil inductive power transfer is the state-of-the-art solution to power multiple miniaturised neural implants. However, the maximum delivered power is limited by the efficiency of the powering link and safety constrains. Here we propose a frequency-s ...

The invention relates to a method for manufacturing an electrode, preferably an implantable electrode array comprising the following steps: Applying (101) a layer of electrically conducting material (4) above a substrate material (1) for forming the electr ...

An insertion device (100; 100') for inserting a retinal prosthesis (200) into the eye of a patient comprises: a handle portion (1; 1') arranged to be grasped by a user of the insertion device (100; 100'), a cannula element (12; 12') arranged to be inserted ...

Neurotechnology includes artificial devices integrated with the neural tissue to mitigate the burden of neurological and mental disorders. This field has significantly expanded its range of applications thanks to the development of flexible, stretchable an ...

Off-stoichiometry thiol-ene-epoxy (OSTE+) thermosets show low permeability to gases and little absorption of dissolved molecules, allow direct low-temperature dry bonding without surface treatments, have a low Young's modulus, and can be manufactured via U ...

A fundamental challenge in neuroengineering is determining a proper artificial input to a sensory system that yields the desired perception. In neuroprosthetics, this process is known as artificial sensory encoding, and it holds a crucial role in prostheti ...

Objective. Retinal prostheses hold the potential to restore artificial vision in blind patients suffering from outer retinal dystrophies. The optimal number, density and coverage of the electrodes that a retinal prosthesis should have to provide adequate a ...

In neurostimulation, wireless power transfer is an efficient technology to overcome several limitations affecting medical devices currently used in clinical practice. Several methods were developed over the years for wireless power transfer. In this review ...

There is growing interest in organic semiconductor devices for light-mediated neuromodulation, such as for retinal stimulation. Here, the key working principles of these devices are discussed, as well as promising applications and outstanding challenges fo ...

A modular multiple frequency coils inductive link system to wirelessly provide power for at least a medical implant at an output of a receiving coil, whereby the receiving coil is configured to be implanted in an organism. The modular multiple frequency co ...

Retinal prostheses hold potential for artificial vision in blind people. Here, authors show that POLYRETINA, a large and high-density photovoltaic epiretinal device, restores light-evoked cortical responses in blind Gottingen minipigs at safe irradiance le ...

This work shows an ultra-miniaturised and ultra-low-power CMOS current driver for biphasic intracortical microstimulation. The CMOS driver is composed of a leakage-based voltage-to-current converter and an H-bridge circuit providing biphasic charge-balance ...

Diego Ghezzi

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Spatially selective activation of the visual cortex via intraneural stimulation of the optic nerve

Virtual reality validation of naturalistic modulation strategies to counteract fading in retinal stimulation

All-Printed Electrocorticography Array for In Vivo Neural Recordings

Engineering Materials for Neurotechnology

Editorial: Nanomaterials for Communicating With the Brain

Questions about the role of P3HT nanoparticles in retinal stimulation

A Frequency-Switching Inductive Power Transfer System for Wireless, Miniaturised and Large-Scale Neural Interfaces

Implantable electrode and method for manufacturing

Insertion device for inserting deformable prosthesis into an eye

Transient electronics: new opportunities for implantable neurotechnology

Conformable neural interface based on off-stoichiometry thiol-ene-epoxy thermosets

An actor-model framework for visual sensory encoding

Virtual reality simulation of epiretinal stimulation highlights the relevance of the visual angle in prosthetic vision

Miniaturised Wireless Power Transfer Systems for Neurostimulation: A Review

Organic semiconductors for light-mediated neuromodulation

A modular multiple frequency inductive link to wirelessly power multiple miniaturized implants

POLYRETINA restores light responses in vivo in blind Gottingen minipigs

Organic electronics for neuroprosthetics

Ultra-Miniaturised CMOS Current Driver for Wireless Biphasic Intracortical Microstimulation

Epiretinal photovoltaic prosthesis with high pixel density