Anne-Laure Mahul MellierExpertise
Cellular Biology: Cell culture of mammalian cell lines (U2OS, N2a, M17, SH-S5Y5, Cos, HeLa, HEK, MCF7), Astrocytic and neuronal primary cultures (hippocampus, cortex, striatum, midbrain) from P0 mouse or rat pups or from E16-E19 mice embryos, iPSC neuronal cultures (proliferation, passaging, differentiation in iNeurons or iDopaminergic neurons), Cellular transfection (DNA plasmid, siRNA, shRNA), Lentiviruses production and infection of neuronal primary cultures or mammalian cell lines, Samples pre
Fosco Bernasconi2014-Present:
post-doc at the EPFL, Laboratory of Congitive Neuroscience.
2012-2014:
Postdoctoral Research Associate, Charité University Medicine, Berlin, Germany.
2012:
Postdoctoral Research Associate,Psychiatric University Hospital (PUK), Zurich, Switzerland.
2008-2011:
PhD in Neurosciences,Lemanic Neurosciences Doctoral School, Faculty of Biology and Medicine, Lausanne University, Switzerland.
2007-2008:
Master in Medical Biology,Faculty of Biology & Medicine, Lausanne University,Switzerland.
Quentin BarraudExpertise
Translational neuroscience · Neuromodulation · Spinal cord injury & Parkinson’s disease · Multi-omics (single-cell, spatial transcriptomics, 3D cleared-tissue imaging) · Preclinical platform management
Mission
To develop, coordinate, and supervise the preclinical activities of .NeuroRestore at EPFL, integrating innovative neuromodulation, gene therapy, and multi-omic strategies. To ensure regulatory compliance of all animal work, support scientific teams in experimental design, and build bridges b
Romain GuietExpertise
Development of BioImage Analysis workflows and algorithms to extract quantitative data from microscopy images.BioSample Preparation : in vitro cell, organoid, time-lapse, fixation, staining strategies, actin, mitochondria, fluorescent protein expressionBioImage Acquisition : Widefield, Confocal, Whole Slide Imaging, Super-resolution (SIM, STORM, STED), FRET, FRAP, FLIMBioImage Analysis: Colocalisation analysis, Deconvolution, Time-lapse , Whole Slide ImagingTools & Software: ImageJ/Fiji, QuPath, i
Silvestro MiceraShort biographical sketch Silvestro Micera received the University degree (Laurea) in Electrical Engineering from the University of Pisa, in 1996, and the Ph.D. degree in Biomedical Engineering from the Scuola Superiore Sant'Anna, in 2000. From 2000 to 2009, he has been an Assistant Professor of BioRobotics at the Scuola Superiore Sant'Anna where he is now the Head of the Neural Engineering group. In 2007 he was a Visiting Scientist at the Massachusetts Institute of Technology, Cambridge, USA with a Fulbri
Werner Alfons Hilda Van GeitWerner is the Group Leader of the Cells team within the Simulation Neuroscience Division in Blue Brain.
The goal of his team is to build the single cell models which are the building blocks of the larger network models used in the Blue Brain Project. The first step when building these cell models consists of reconstructing, analysing and artificially recreating neuron morphologies. Next, a biophysically detailed electrical model for the different cell types is built. For the latter the team uses automated parameter optimisation tools like Blue Brain’s open source BluePyOpt tool, but they are also active in extending and developing other Blue Brain software packages related to single cells.
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