Anne-Laure Mahul MellierExpertise
Cellular Biology: Cell culture of mammalian cell lines (U2OS, N2a, M17, SH-S5Y5, Cos, HeLa, HEK, MCF7), Astrocytic and neuronal primary cultures (hippocampus, cortex, striatum, midbrain) from P0 mouse or rat pups or from E16-E19 mice embryos, iPSC neuronal cultures (proliferation, passaging, differentiation in iNeurons or iDopaminergic neurons), Cellular transfection (DNA plasmid, siRNA, shRNA), Lentiviruses production and infection of neuronal primary cultures or mammalian cell lines, Samples pre
Fosco BernasconiBio I am a neuroscientist, interested in consciousness. I obtained a Ph.D. in neuroscience with Stéphanie Clarke & Lucas Spierer in Lausanne (Switzerland) in 2012. I then worked with Franz X Vollenweider in Zurich (Switzerland), and Niko A Busch in Berlin (Germany). Since 2014, I am working with Olaf Blanke at the EPFL & école polytechnique fédérale de Lausanne in Geneva. Currently, we investigate the role of altered (bodily) self-consciousness in aberrant perceptions, notably observed in psychiatric and n
Quentin BarraudExpertise
Translational neuroscience · Neuromodulation · Spinal cord injury & Parkinson’s disease · Multi-omics (single-cell, spatial transcriptomics, 3D cleared-tissue imaging) · Preclinical platform management · Swiss animal research regulation
Mission
To develop, coordinate, and supervise the preclinical activities of .NeuroRestore at EPFL, integrating innovative neuromodulation, gene therapy, and multi-omic strategies. To ensure regulatory compliance of all animal work, support scientific teams in exper
Romain GuietExpertise
Development of BioImage Analysis workflows and algorithms to extract quantitative data from microscopy images.BioSample Preparation : in vitro cell, organoid, time-lapse, fixation, staining strategies, actin, mitochondria, fluorescent protein expressionBioImage Acquisition : Widefield, Confocal, Whole Slide Imaging, Super-resolution (SIM, STORM, STED), FRET, FRAP, FLIMBioImage Analysis: Colocalisation analysis, Deconvolution, Time-lapse , Whole Slide ImagingTools & Software: ImageJ/Fiji, QuPath, i
Silvestro MiceraEnseignement et PhD Doctorant·es actuel·les Johannes Sebastiaan Nieuwenhuis, Mouhamed Zorkot, Angela Braccia, Jonathan Muheim, Xiangyu Xu A dirigé les thèses EPFL de Elvira Pirondini, Andrea Crema, Marco Bonizzato, Sophie Marie Marthe Wurth, Edoardo D'Anna, Emanuele Formento, Jenifer Cléa Miehlbradt, Flavio Raschella, Nawal Kinany, Théo Lemaire, Marion Aimée Geneviève Badi-Dubois, Tristan Jean Robin Barjavel, Vincent Alexandre Mendez, Outman Akouissi, Giulia Dominijanni, Simone Romeni, Franklin Leong, Ele
Werner Alfons Hilda Van GeitWerner is the Group Leader of the Cells team within the Simulation Neuroscience Division in Blue Brain.
The goal of his team is to build the single cell models which are the building blocks of the larger network models used in the Blue Brain Project. The first step when building these cell models consists of reconstructing, analysing and artificially recreating neuron morphologies. Next, a biophysically detailed electrical model for the different cell types is built. For the latter the team uses automated parameter optimisation tools like Blue Brain’s open source BluePyOpt tool, but they are also active in extending and developing other Blue Brain software packages related to single cells.
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