Romain GuietExpertise
Development of BioImage Analysis workflows and algorithms to extract quantitative data from microscopy images.BioSample Preparation : in vitro cell, organoid, time-lapse, fixation, staining strategies, actin, mitochondria, fluorescent protein expressionBioImage Acquisition : Widefield, Confocal, Whole Slide Imaging, Super-resolution (SIM, STORM, STED), FRET, FRAP, FLIMBioImage Analysis: Colocalisation analysis, Deconvolution, Time-lapse , Whole Slide ImagingTools & Software: ImageJ/Fiji, QuPath, i
Anne-Laure Mahul MellierExpertise
Cellular Biology: Cell culture of mammalian cell lines (U2OS, N2a, M17, SH-S5Y5, Cos, HeLa, HEK, MCF7), Astrocytic and neuronal primary cultures (hippocampus, cortex, striatum, midbrain) from P0 mouse or rat pups or from E16-E19 mice embryos, iPSC neuronal cultures (proliferation, passaging, differentiation in iNeurons or iDopaminergic neurons), Cellular transfection (DNA plasmid, siRNA, shRNA), Lentiviruses production and infection of neuronal primary cultures or mammalian cell lines, Samples pre
Bruno Emanuel Ferreira De Sousa CorreiaThroughout my PhD and postdoctoral studies I was trained in world-renowned laboratories and institutions in the United States of America (University of Washington and The Scripps Research Institute). Very early in my scientific career I found out my fascination about protein structure and function. My PhD studies evolved in the direction of immunogen design and vaccine engineering which sparked my interest in the many needs and opportunities in vaccinology and translational research. My efforts resulted in an enlightening piece of work where for the first time, computationally designed immunogens elicited potent neutralizing antibodies. During my postdoctoral studies I joined a chemical biology laboratory at the Scripps Research Institute. In this stage I developed novel chemoproteomics methods for the identification of protein-small molecule interaction sites in complex proteomes. In March 2015, I joined the École Polytechnique Fédérale de Lausanne (EPFL) – Switzerland as a tenure track assistant professor. The focus of my research group is to develop computational tools for protein design with particular emphasis in applying these strategies to immunoengineering (e.g. vaccine and cancer immunotherapy). The activities in my laboratory focus on computational design methods development and experimental characterization of the designed proteins. Our laboratory has been awarded with 2 prestigious research grants from the European Research Council. Lastly, I have been awarded the prize for best teacher of Life sciences in 2019.
Johanni Michael BreaTeaching & PhD PhD Students Aude Maier, Lucas Louis Gruaz, Flavio Martinelli Courses Artificial intelligence and society HUM-286 This course integrates social sciences and humanities with engineering sciences, and introduces students to the social, technical and political issues surrounding artificial intelligence. Biological data science II : machine learning BIO-322 Students understand basic concepts and methods of machine learning. They can describe them in mathematical
Quentin BarraudExpertise
Translational neuroscience · Neuromodulation · Spinal cord injury & Parkinson’s disease · Multi-omics (single-cell, spatial transcriptomics, 3D cleared-tissue imaging) · Preclinical platform management
Mission
To develop, coordinate, and supervise the preclinical activities of .NeuroRestore at EPFL, integrating innovative neuromodulation, gene therapy, and multi-omic strategies. To ensure regulatory compliance of all animal work, support scientific teams in experimental design, and build bridges b
Berend SmitBerend Smit received an MSc in Chemical Engineering in 1987 and an MSc in Physics both from the Technical University in Delft (the Netherlands). He received in 1990 cum laude PhD in Chemistry from Utrecht University (the Netherlands). He was a (senior) Research Physicists at Shell Research from 1988-1997, Professor of Computational Chemistry at the University of Amsterdam (the Netherlands) 1997-2007.
In 2004 Berend Smit was elected Director of the European Center of Atomic and Molecular Computations (CECAM) Lyon France. Since 2007 he is Professor of Chemical Engineering and Chemistry at U.C. Berkeley and Faculty Chemist at Materials Sciences Division, Lawrence Berkeley National Laboratory. Since 2014 he has been director of the Energy Center at EPFL.
Fosco Bernasconi2014-Present:
post-doc at the EPFL, Laboratory of Congitive Neuroscience.
2012-2014:
Postdoctoral Research Associate, Charité University Medicine, Berlin, Germany.
2012:
Postdoctoral Research Associate,Psychiatric University Hospital (PUK), Zurich, Switzerland.
2008-2011:
PhD in Neurosciences,Lemanic Neurosciences Doctoral School, Faculty of Biology and Medicine, Lausanne University, Switzerland.
2007-2008:
Master in Medical Biology,Faculty of Biology & Medicine, Lausanne University,Switzerland.
Maud EhrmannMaud Ehrmann is a research scientist at EPFL’s Digital Humanities Laboratory lead by Prof.
Frédéric Kaplan
. She holds a PhD in Computational Linguistics from the Paris Diderot Universtiy (Paris 7) and has been engaged in a large number of scientific projects centred on information extraction and text analysis, both for present-time and historical documents. Her main research interests span Natural Language Processing and Digital Humanities and include, among others, historical text annotation, historical data processing and representation, named entity recognition, and multilingual linguistic resources creation.
Her current work at the DHLAB focuses on
‘impresso - Media Monitoring of the Past’
, a SNF sinergia project she initiated with
Marten Düring
(
C2DH
) and
Simon Clematide
(
ICL
) and which aims at enabling critical analysis of historical newspapers. In addition to the overall project management, her contributions to this project include system design and data management, annotation and benchmarking and named entity processing. Besides, she participates to the activities of the
Venice Time Machine
, working particularly on information extraction and knowledge representation tasks. Previously, she worked on the
Garzoni
project where she supervised and contributed to the development of a web-based transcription and annotation interface - in collaboration with Orlin Topalov, and built a linked data-based historical knowledge base. She also contributed to the
Le Temps Digital Archives project
.
Prior to joining the DHLAB, she worked at the
Linguistics Computing Laboratory
at the Sapienza University of Rome with Roberto Navigli, where she worked on the
BabelNet
resource - a very large multilingual encyclopaedic dictionary and semantic network - and contributed to the
LIDER
project. Before that, she has been working for four years at the European Commission’s Joint Research Centre in Ispra, Italy, as member of the OPTIMA unit (now
Text and Data mining
unit), which develops innovative and application-oriented solutions for retrieving and extracting information from the Internet with a focus on high multilinguality. Together with Erik van der Goot,
Ralf Steinberger
, Hristo Tanev, Leo della Rocca and many others, she contributed to the development of the
Europe Media Monitor
(EMM). Prior, she worked at the Xerox Europe Research Centre in Grenoble, France (now
Naver Labs Europe
) in the Parsing & Semantics group led by Frédérique Segond, first as PhD candidate supported through a CIFRE grant under the supervision of
Caroline Brun
and
Bernard Victorri
, then as a post-doctoral researcher. There her research focused mainly on the automatic processing and fine-grained analysis of entities of interest, specifically named entities and temporal expressions.
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