Romain GuietExpertise
Development of BioImage Analysis workflows and algorithms to extract quantitative data from microscopy images.BioSample Preparation : in vitro cell, organoid, time-lapse, fixation, staining strategies, actin, mitochondria, fluorescent protein expressionBioImage Acquisition : Widefield, Confocal, Whole Slide Imaging, Super-resolution (SIM, STORM, STED), FRET, FRAP, FLIMBioImage Analysis: Colocalisation analysis, Deconvolution, Time-lapse , Whole Slide ImagingTools & Software: ImageJ/Fiji, QuPath, i
Anne-Laure Mahul MellierExpertise
Cellular Biology: Cell culture of mammalian cell lines (U2OS, N2a, M17, SH-S5Y5, Cos, HeLa, HEK, MCF7), Astrocytic and neuronal primary cultures (hippocampus, cortex, striatum, midbrain) from P0 mouse or rat pups or from E16-E19 mice embryos, iPSC neuronal cultures (proliferation, passaging, differentiation in iNeurons or iDopaminergic neurons), Cellular transfection (DNA plasmid, siRNA, shRNA), Lentiviruses production and infection of neuronal primary cultures or mammalian cell lines, Samples pre
Bruno Emanuel Ferreira De Sousa CorreiaThroughout my PhD and postdoctoral studies I was trained in world-renowned laboratories and institutions in the United States of America (University of Washington and The Scripps Research Institute). Very early in my scientific career I found out my fascination about protein structure and function. My PhD studies evolved in the direction of immunogen design and vaccine engineering which sparked my interest in the many needs and opportunities in vaccinology and translational research. My efforts resulted in an enlightening piece of work where for the first time, computationally designed immunogens elicited potent neutralizing antibodies. During my postdoctoral studies I joined a chemical biology laboratory at the Scripps Research Institute. In this stage I developed novel chemoproteomics methods for the identification of protein-small molecule interaction sites in complex proteomes. In March 2015, I joined the École Polytechnique Fédérale de Lausanne (EPFL) – Switzerland as a tenure track assistant professor. The focus of my research group is to develop computational tools for protein design with particular emphasis in applying these strategies to immunoengineering (e.g. vaccine and cancer immunotherapy). The activities in my laboratory focus on computational design methods development and experimental characterization of the designed proteins. Our laboratory has been awarded with 2 prestigious research grants from the European Research Council. Lastly, I have been awarded the prize for best teacher of Life sciences in 2019.
Johanni Michael BreaTeaching & PhD PhD Students Aude Maier, Lucas Louis Gruaz, Flavio Martinelli Courses Artificial intelligence and society HUM-286 This course integrates social sciences and humanities with engineering sciences, and introduces students to the social, technical and political issues surrounding artificial intelligence. Biological data science II : machine learning BIO-322 Students understand basic concepts and methods of machine learning. They can describe them in mathematical
Quentin BarraudExpertise
Translational neuroscience · Neuromodulation · Spinal cord injury & Parkinson’s disease · Multi-omics (single-cell, spatial transcriptomics, 3D cleared-tissue imaging) · Preclinical platform management
Mission
To develop, coordinate, and supervise the preclinical activities of .NeuroRestore at EPFL, integrating innovative neuromodulation, gene therapy, and multi-omic strategies. To ensure regulatory compliance of all animal work, support scientific teams in experimental design, and build bridges b
Berend SmitBerend Smit received an MSc in Chemical Engineering in 1987 and an MSc in Physics both from the Technical University in Delft (the Netherlands). He received in 1990 cum laude PhD in Chemistry from Utrecht University (the Netherlands). He was a (senior) Research Physicists at Shell Research from 1988-1997, Professor of Computational Chemistry at the University of Amsterdam (the Netherlands) 1997-2007.
In 2004 Berend Smit was elected Director of the European Center of Atomic and Molecular Computations (CECAM) Lyon France. Since 2007 he is Professor of Chemical Engineering and Chemistry at U.C. Berkeley and Faculty Chemist at Materials Sciences Division, Lawrence Berkeley National Laboratory. Since 2014 he has been director of the Energy Center at EPFL.
Fosco Bernasconi2014-Present:
post-doc at the EPFL, Laboratory of Congitive Neuroscience.
2012-2014:
Postdoctoral Research Associate, Charité University Medicine, Berlin, Germany.
2012:
Postdoctoral Research Associate,Psychiatric University Hospital (PUK), Zurich, Switzerland.
2008-2011:
PhD in Neurosciences,Lemanic Neurosciences Doctoral School, Faculty of Biology and Medicine, Lausanne University, Switzerland.
2007-2008:
Master in Medical Biology,Faculty of Biology & Medicine, Lausanne University,Switzerland.
Maud EhrmannMaud Ehrmann is a research scientist at EPFL’s Digital Humanities Laboratory lead by Prof.
Frédéric Kaplan
. She holds a PhD in Computational Linguistics from the Paris Diderot Universtiy (Paris 7) and has been engaged in a large number of scientific projects centred on information extraction and text analysis, both for present-time and historical documents. Her main research interests span Natural Language Processing and Digital Humanities and include, among others, historical text annotation, historical data processing and representation, named entity recognition, and multilingual linguistic resources creation.
Her current work at the DHLAB focuses on
‘impresso - Media Monitoring of the Past’
, a SNF sinergia project she initiated with
Marten Düring
(
C2DH
) and
Simon Clematide
(
ICL
) and which aims at enabling critical analysis of historical newspapers. In addition to the overall project management, her contributions to this project include system design and data management, annotation and benchmarking and named entity processing. Besides, she participates to the activities of the
Venice Time Machine
, working particularly on information extraction and knowledge representation tasks. Previously, she worked on the
Garzoni
project where she supervised and contributed to the development of a web-based transcription and annotation interface - in collaboration with Orlin Topalov, and built a linked data-based historical knowledge base. She also contributed to the
Le Temps Digital Archives project
.
Prior to joining the DHLAB, she worked at the
Linguistics Computing Laboratory
at the Sapienza University of Rome with Roberto Navigli, where she worked on the
BabelNet
resource - a very large multilingual encyclopaedic dictionary and semantic network - and contributed to the
LIDER
project. Before that, she has been working for four years at the European Commission’s Joint Research Centre in Ispra, Italy, as member of the OPTIMA unit (now
Text and Data mining
unit), which develops innovative and application-oriented solutions for retrieving and extracting information from the Internet with a focus on high multilinguality. Together with Erik van der Goot,
Ralf Steinberger
, Hristo Tanev, Leo della Rocca and many others, she contributed to the development of the
Europe Media Monitor
(EMM). Prior, she worked at the Xerox Europe Research Centre in Grenoble, France (now
Naver Labs Europe
) in the Parsing & Semantics group led by Frédérique Segond, first as PhD candidate supported through a CIFRE grant under the supervision of
Caroline Brun
and
Bernard Victorri
, then as a post-doctoral researcher. There her research focused mainly on the automatic processing and fine-grained analysis of entities of interest, specifically named entities and temporal expressions.
Sara BonellaExpertise
Simulation and modelling of condensed phase systems, quantum and classical dynamics and statistical mechanics, adiabatic dynamics for classical polarizable models and first principles simulations, classical charge transport for systems in external magnetic fields.
Expertise
Simulation and modelling of condensed phase systems, quantum and classical dynamics and statistical mechanics, adiabatic dynamics for classical polarizable models and first principles simulations, classical charge transport for
Jan Sickmann HesthavenProf. Hesthaven received an M.Sc. in computational physics from the Technical University of Denmark (DTU) in August 1991. During the studies, the last 6 months of 1989 was spend at JET, the european fusion laboratory in Culham, UK. Following graduation, he was awarded a 3 year fellowship to begin work towards a Ph.D. at Riso National Laboratory in the Department of Optics and Fluid Dynamics. During the 3 years of study, the academic year of 1993-1994 was spend in the Division of Applied Mathematics at Brown University and three 3 months during the summer of 1994 in Department of Mathematics and Statistics at University of New Mexico. In August 1995, he recieved a Ph.D. in Numerical Analysis from the Institute of Mathematical Modelling (DTU). Following graduation in August 1995, he was awarded an NSF Postdoctoral Fellowship in Advanced Scientific Computing and was approinted Visiting Assistant Professor in the Division of Applied Mathematics at Brown University. In December of 1996, he was appointed consultant to the Institute of Computer Applications in Science and Engineering(ICASE) at NASA Langley Research Center (NASA LaRC). As of July 1999, he was appointed Assistant Professor of Applied Mathematics, in September 2000 he was awarded an Alfred P. Sloan Fellowship, as of July 2001 he was awarded a Manning Assistant Professorship, and in March 2002, he was awarded an NSF Career Award. In January 2003, he was promoted to Associate Professor of Applied Mathematics with tenure and in May 2004 he was awarded Philip J. Bray Award for Excellence in Teaching in the Sciences (the highest award given for teaching excellence in all sciences at Brown University). He was promoted to Professor of Applied Mathematics as of July 2005. From October 2006 to June 2013, he was the Founding Director of the Center for Computation and Visualization (CCV) at Brown University. As of October 2007, he holds the (honorary) title of Professor (Adjunct) at the Technical University of Denmark. In November 2009, he successfully defended his dr.techn thesis at the Technical University of Denmark and was rewarded the degree of Doctor Technices -- the highest academic distinction awarded based on ... substantial and lasting contributions that has helped to move the research area forward and penetrated into applications. As grant Co-PI he served from Aug 2010 to June 2013 as Deputy Director of the Institute of Computational and Experimental Research in Mathematics (ICERM), the newest NSF Mathematical Sciences Research Institute. After having spend his entire academic career at Brown University, Prof Hesthaven decided to pursue new challenges and joined the Mathematics Institute of Computational Science and Engineering (MATHICSE) at Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland in July 2013. In March 2014 he was elected SIAM Fellow for contributions to high-order methods for partial differential equations.
James Richard LarusExpertise
James Larus is a Professor Emeritus and former Dean of the School of Computer and Communication Sciences (IC) at EPFL (école Polytechnique Fédérale de Lausanne). Before joining IC in October 2013, Larus was a researcher, manager, and director in Microsoft Research for over 16 years and an Assistant and Associate Professor in the Computer Sciences Department at the University of Wisconsin, Madison.Larus has been an active contributor to numerous communities. He published over 100 papers (with 14 be
Luciano Andres AbriataExpertise
Protein NMRNMR of paramagnetic systemsMetalloproteinsBiomolecular SpectroscopyStructural BiologyStructural BioinformaticsMolecular Modeling
ResearchPapers Link to Google Scholar
Teaching & PhD Courses Basic and advanced NMR - Level 1 A (EPFL) CH-601(x) Basic theoretical and experimental aspects of NMR will be taught. Students will be familarized with modern NMR spectrometers. Basic and advanced NMR - Level 2 (EPFL) CH-703 The goal is to give a sound theoretical an
Eduardo Martin MoraudExpertise
The Moraud group develops closed-loop neuromodulation therapies for movement disorders, particularly Parkinson’s disease, with a specific emphasis on gait and balance impairments. The group integrates multimodal monitoring of motor and neural biomarkers to enable real-time decoding of dysfunctional states and their underlying neural dynamics, advancing a circuit-level understanding of locomotor control and informing the design of state-dependent adaptive therapies.
Mission
The group aims to transl
Andreas PautzTeaching & PhD PhD Students Sofia Portolan, Michel Saliba, Bishal Torrente, Alexis Paul Boris Claude Dupont-Bembinoff, Cynthia Camila Güttlein Past EPFL PhD Students Ting Zhu, Vladimir Vladimirov Brankov, Boris Aviv Hombourger, Damar Canggih Wicaksono, Petra Mala, Adolfo Rais, Valentyn Bykov, Daniel Jerôme Siefman, Evgeny Nikitin, Dionysios Chionis, Oskari Ville Pakari, Friederike Bostelmann, Jiani Gao, Efstathios Vlassopoulos, Alessandro Scolaro, Stefan Radman, Alexander Aures, Lubomír Bures, Ahmed Salah
Isabella Di LenardoPh.D. in Theories and Art History. Isabella di Lenardo is senior scientist in Digital Humanities and Urban History. Her research activity is focused on digital tools and methods applied to Urban History. She is an expert in ancient cartography, city representations, cadastral sources interpreted through digital modeling, extraction and analysis systems.She's also interested in network analysis questioning the production and circulation of artistic and architectural knowledge in Europe XVIth – XVIIIth centuries in particular on North-South relationships and influences. The development of collaboration projects with European institutions and the activity carried out on various initiatives supported by the European Commission have allowed her to acquire specialism in the field of science applied to heritage, developing in particular specific skills for the enhancement of Cultural Heritage through digital tools. She leads projects in collaboration with Bibliothèque national de France (Paris), Institut National d’Histoire de l’Art (Paris), Ecole nationale des chartes (Paris), Université Paris I Panthéon-Sorbonne, Centre Allemand d’Histoire de l’Art (Paris), Musée du Louvre, Archives Nationales de Paris, Bibliothèque Historique de la Ville de Paris, Réunion des Musées Nationaux. She supervised all the urban modeling simulations for the Venice Time Machine project and acted as content curator for all the exhibitions (Venice Biennale, Grand Palais-Paris, Datasquare - ArtLab-Lausanne, Museo Correr-Venice). She was Head of “Replica” project : digitizing 1 million photos of artworks in the Fondazione Giorgio Cini (Venice) and visual patterns extraction through a search engine for visual similarities. She has a Ph.D in Art History and also studied Archaeology and Urban Studies. She has published essays and articles about Venetian Art and Urban History and participated in many Art exhibitions in European museums. She coordinated summer schools and workshops about Digital Tools for Art History and Urban History. She attended conferences on digital methods for History in universities and patrimonial institutions.
