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Stéphanie Lacour

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Related publications (122)

Optical cuff for optogenetic control of the peripheral nervous system

Léonie Asboth, Frédéric Pierre Gérald Michoud, Stéphanie Lacour, Loïc Sottas, Grégoire Courtine

Objective. Nerves in the peripheral nervous system (PNS) contain axons with specific motor, somatosensory and autonomic functions. Optogenetics offers an efficient approach to selectively activate axons within the nerve. However, the heterogeneous nature o ...

2018

Long-term functionality of a soft electrode array for epidural spinal cord stimulation in a minipig model

Giuseppe Schiavone, Nicolas Vachicouras, Florian Dylan Fallegger, Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Fabien Bertrand Paul Wagner, Beatrice Barra, Jocelyne Bloch, Xiaoyang Kang

IEEE2018

A Method to Form Smooth Films of Liquid Metal Supported by Elastomeric Substrate

Stéphanie Lacour, Arthur Edouard Hirsch

Several methods are proposed to manipulate and pattern liquid metal films into elastic conductors but all lack precise control over the film thickness and roughness, thereby limiting its uniformity, stability, and reproducibility. Here, an approach relying ...

2018

Engineering reversible elasticity in ductile or brittle thin films and products resulting from said engineering

Nicolas Vachicouras, Stéphanie Lacour, Christina Myra Tringides

The present invention relates to how to engineer reversible elasticity in thin films and/or layers and/or substrates, using a repeated Y-shaped motif, which is cut out throughout the film and/or layer and/or substrate. As an example, using a 75 μm thick po ...

2018

Long-term functionality of a soft electrode array for epidural spinal cord stimulation in a minipig model

Giuseppe Schiavone, Nicolas Vachicouras, Florian Dylan Fallegger, Stéphanie Lacour, Grégoire Courtine, Marco Capogrosso, Fabien Bertrand Paul Wagner, Beatrice Barra, Jocelyne Bloch, Xiaoyang Kang

Long-term biointegration of man-made neural interfaces is influenced by the mechanical properties of the implant materials. Substantial experimental work currently aims at replacing conventional hard implant materials with soft alternatives that can favour ...

IEEE2018

Controlled Sub-Micrometer Hierarchical Textures Engineered in Polymeric Fibers and Microchannels via Thermal Drawing

Stéphanie Lacour, Dang Tùng Nguyen, Fabien Sorin, Alexis Gérald Page, Wei Yan, Alba Carla De Luca, Yunpeng Qu, Marco Volpi

The controlled texturing of surfaces at the micro- and nanoscales is a powerful method for tailoring how materials interact with liquids, electromagnetic waves, or biological tissues. The increasing scientific and technological interest in advanced fibers ...

2017

Engineering reversible elasticity in ductile and brittle thin films supported by a plastic foil

Nicolas Vachicouras, Stéphanie Lacour, Christina Myra Tringides

Reversible deformation is a unique property of elastic materials. Here, we design and fabricate highly stretchable multilayered films by patterning Y-shaped motifs through films of non- elastic materials, e.g. plastics, metals, ceramics. By adjusting the g ...

Elsevier Science Bv2017

Electronic Dura Mater Meddling in the Central Nervous System

Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch

IMPORTANCE A growing number of neurologic treatments rely on neural implants capable of delivering electrical and chemical stimulation to targeted regions of the central nervous system for extended periods. OBJECTIVE To assess the potential of a novel clas ...

Amer Medical Assoc2017

In vitro evaluation of gel-encapsulated adipose derived stem cells: Biochemical cues for in vivo peripheral nerve repair

Stéphanie Lacour

Adipose‐derived stem cells (ASC) are becoming one of the most exploited cells in peripheral nerve repair. They are fast‐growing and able to protect neurons from apoptosis; they can reduce postinjury latency and the risk of muscle atrophy. This study evalua ...

Wiley-Blackwell2017

Method for the electrical passivation of electrode arrays and/or conductive paths in general, and a method for producing stretchable electrode arrays and/or stretchable conductive paths in general

Stéphanie Lacour, Ivan Rusev Minev

A method produces a conductive paste comprising 15-20% by weight of PDMS and 80-85% by weight of metallic micro-nano particles, wherein the conductive paste is obtained by repeated addition of singular doses of PDMS to a heptane diluted PDMS low viscosity ...

2017

Method for manufacturing electrical conductors, and electrical conductors manufactured according to same

Stéphanie Lacour, Hadrien Olivier Michaud, Arthur Edouard Hirsch, Ivan Rusev Minev

A method for manufacturing an electrical conductor 43 and an electrical conductor 43 manufactured according to the method, said method comprising: providing a substrate 30; depositing a solid metal conductive layer or film 40 on said substrate 30; Depositi ...

2017

Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury

Léonie Asboth, Jérôme Gandar, Stéphanie Lacour, Arthur Edouard Hirsch, Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Ivan Rusev Minev, Rubia van den Brand, Quentin Barraud, Simone Ellen Joze Duis, Eduardo Martin Moraud, Pavel Musienko, Marco Capogrosso, Natalia Pavlova, Julie Kreider, Laetitia Danielle Philippine Baud, Andrea Mortera, Jocelyne Bloch

Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in animal models and humans. However, the physiological principles underlying the effect of this intervention remain poorly understood, which has limited the ther ...

Nature Publishing Group2016

Performance of Indium Gallium Zinc Oxide Thin-Film Transistors in Saline Solution

Stéphanie Lacour

Transistors are often envisioned as alternative transducing devices to microelectrodes to communicate with the nervous system. Independently of the selected technology, the transistors should have reliable performance when exposed to physiological conditio ...

Springer Verlag2016

A Wireless System with Stimulation and Recording Capabilities for Interfacing Peripheral Nerves in Rodents

Qiuting Huang, Amélie Anne Guex, Frédéric Pierre Gérald Michoud, Stéphanie Lacour, Noé Brun

Considerable progress has been made in the last decade in implantable bioelectronic neurosystems. Yet most neural implants are used in acute and tethered experimental conditions. Here, we present a preliminary prototype of a multichannel system for simulta ...

2016

Design and Functional Evaluation of an Epidermal Strain Sensing System for Hand Tracking

Laurent Mirko Dejace, Stéphanie Lacour, Hadrien Olivier Michaud, Séverine Claire Marie De Mulatier

2016

Materials and technologies for soft implantable neuroprostheses

Stéphanie Lacour, Grégoire Courtine

Implantable neuroprostheses are engineered systems designed to restore or substitute function for individuals with neurological deficits or disabilities. These systems involve at least one uni-or bidirectional interface between a living neural tissue and a ...

Nature Publishing Group2016

Synthetic skin for recording and modulating physiological activities

Stéphanie Lacour, Arthur Edouard Hirsch, Grégoire Courtine, Ivan Rusev Minev, Pavel Musienko

A method for producing a device adapted to be implanted into the human body for purposes such as neural stimulation, sensing or the like, and device produced according to said method, said method comprising: providing a stretchable layer or membrane (21) o ...

2016

Intrinsically Stretchable Biphasic (Solid–Liquid) Thin Metal Films

Stéphanie Lacour, Hadrien Olivier Michaud, Arthur Edouard Hirsch, Aaron Powers Gerratt, Séverine Claire Marie De Mulatier

Stretchable biphasic conductors are formed by physical vapor deposition of gallium onto an alloying metal film. The properties of the photolithography-compatible thin metal films are highlighted by low sheet resistance (0.5 Ω sq−1) and large stretchability ...

Wiley-V C H Verlag Gmbh2016

Soft metal constructs for large strain sensor membrane

Joan Teixidor, Stéphanie Lacour, Hadrien Olivier Michaud

Thin gold films on silicone display large reversible change in electrical resistance upon stretching. Eutectic liquid metal conductors maintain bulk metal conductivity, even upon extensive elongation. When integrated together, the soft metals enable multid ...

Iop Publishing Ltd2015

Biomaterials. Electronic dura mater for long-term multimodal neural interfaces

Tomislav Milekovic, Léonie Asboth, Jérôme Gandar, Nicolas Vachicouras, Stéphanie Lacour, Arthur Edouard Hirsch, Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Ivan Rusev Minev, Quentin Barraud, Simone Ellen Joze Duis, Eduardo Martin Moraud, Pavel Musienko, Marco Capogrosso, Natalia Pavlova

The mechanical mismatch between soft neural tissues and stiff neural implants hinders the long-term performance of implantable neuroprostheses. Here, we designed and fabricated soft neural implants with the shape and elasticity of dura mater, the protectiv ...

American Association for the Advancement of Science2015

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