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Carlotta Guiducci

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Related publications (39)

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Comparison against current standards of a DNA aptamer for the label-free quantification of tobramycin in human sera employed for therapeutic drug monitoring

Carlotta Guiducci, Anna Ferretti, Enrico Tenaglia

2018

Hybridization chain reaction performed on a metal surface as a means of signal amplification in SPR and electrochemical biosensors

Carlotta Guiducci, Fabio Mario Spiga

A more specific and intense signal is desirable for most kinds of biosensors for biomedical or environmental applications, and it is especially so for label-free biosensors. In this paper, we show that hybridization chain reaction (HCR) can be exploited fo ...

Elsevier2014

A 0.18 mu m Biosensor Front-End Based on 1/f Noise, Distortion Cancelation and Chopper Stabilization Techniques

Christian Enz, Carlotta Guiducci, Yüksel Temiz, Anna Ferretti

This paper presents a novel sensor front-end circuit that addresses the issues of 1/f noise and distortion in a unique way by using canceling techniques. The proposed front-end is a fully differential transimpedance amplifier (TIA) targeted for current mod ...

Ieee-Inst Electrical Electronics Engineers Inc2013

Die-Level TSV Fabrication Platform for CMOS-MEMS Integration

Yusuf Leblebici, Carlotta Guiducci, Michail Zervas, Yüksel Temiz

This paper reports a new post-CMOS processing platform for die-level through-silicon-via (TSV) fabrication, based on wafer reconstitution from embedded dies, parylene deposition, stencil lithography, and bottom-up electroplating. The goal of this work is t ...

2011

Peak Shift Measurement of Localized Surface Plasmon Resonance by a Portable Electronic System

Luca Benini, Carlotta Guiducci, Enrico Accastelli, Giulia Cappi

In recent years, the characterization of surface molecular layers by localized surface plasmon resonance (LSPR) has attracted a lot of interest thanks to its ability to provide a higher spatial resolution with respect to standard SPR. LSPR can be observed ...

Elsevier2013

Detecting particles flowing through interdigitated 3D microelectrodes

Carlotta Guiducci, Enrico Accastelli, Samuel Kilchenmann, Elena Bianchi, Enrica Rollo

Counting cells in a large microchannel remains challenging and is particularly critical for in vitro assays, such as cell adhesion assays. This paper addresses this issue, by presenting the development of interdigitated three-dimensional electrodes, which ...

Ieee2012

Digital approaches in Electronic biochips

Carlotta Guiducci, Enrico Accastelli, Fabio Mario Spiga

Download Citation Email Print Request Permissions Save to Project Electronic biochips are defined by the merge of integrated electronics, containing diverse sensors, with reaction solution and sample hold in reaction chamber(s). Based on their overall stru ...

IEEE2013

Isothermal multiple displacement amplification of DNA templates in minimally buffered conditions using phi29 polymerase

Carlotta Guiducci, Enrico Tenaglia

The isothermal amplification of DNA in minimally buffered conditions allows to perform and monitor nucleic acid amplification with minimal technological and operative requirements. We show in this work how phi29 can operate multiple displacement amplificat ...

Royal Society of Chemistry2018

Integrating Bio-sensing Functions on CMOS Chips

Yusuf Leblebici, Carlotta Guiducci, Yüksel Temiz, Enrico Accastelli, Giulia Cappi, Anna Ferretti, Elena Bianchi

The paper discusses the recent achievements in the development of chips with integrated sensing of biomolecules. In particular, it focuses on integrated sensing electrodes on silicon and presents innovative solutions for the enhanced robustness of the elec ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2010

Post-cmos processing and 3d integration based on dry-film lithography

Yusuf Leblebici, Carlotta Guiducci, Yüksel Temiz

A method for performing a post processing pattern on a diced chip having a foot-print, comprises the steps of providing a support wafer; applying a first dry film photoresist to the support wafer; positioning a mask corresponding to the footprint of the di ...

2015

Dielectrophoresis detection device

Carlotta Guiducci, Pierre-Emmanuel Marie Thiriet

A dielectrophoretic detection device comprising a chip, with a flow channel having at least one inlet and one outlet, and at least a detection area configured to detect analytes trapped on functionalised beads flowing within said flow channel, a first and ...

2021

Label-Free Detection of Tobramycin in Serum by Transmission-Localized Surface Plasmon Resonance

Carlotta Guiducci, Giulia Cappi, Fabio Mario Spiga, Anna Ferretti

In order to improve the efficacy and safety of treatments, drug dosage needs to be adjusted to the actual needs of each patient in a truly personalized medicine approach. Key for widespread dosage adjustment is the availability of point-of-care devices abl ...

Amer Chemical Soc2015

Multi-Wire Tri-Gate Silicon Nanowires Reaching Milli-pH Unit Resolution in One Micron Square Footprint

Carlotta Guiducci, Enrico Accastelli

The signal-to-noise ratio of planar ISFET pH sensors deteriorates when reducing the area occupied by the device, thus hampering the scalability of on-chip analytical systems which detect the DNA polymerase through pH measurements. Top-down nano-sized tri-g ...

Mdpi Ag2016

Novel Front-End Circuit Architectures for Integrated Bio-Electronic Interfaces

Yusuf Leblebici, Alexandre Schmid, Carlotta Guiducci

2008

Another transistor-based revolution: on-chip qPCR

Carlotta Guiducci, Fabio Mario Spiga

More than 40 years after the invention of semiconductor pH microtransducers known as ISFETs, this transistor-based technology may revolutionize quantitative PCR. ...

Nature Publishing Group2013

Particle-sorting fluidic device and methods for using thereof

Carlotta Guiducci, Kevin Keim, Gloria Porro, Till Jonathan Ryser

Device, system and method for sorting particles comprised into a fluid are disclosed that improve the current settings of deterministic lateral displacement (DLD)-based microfluidic devices, so to sort and detect small particles such as extracellular vesic ...

2022

3D Integration Technology for Lab-on-a-Chip Applications

Yusuf Leblebici, Carlotta Guiducci, Yüksel Temiz, Samuel Kilchenmann

A review is presented of advances and challenges in fully integrated systems for personalised medicine applications. One key issue for the commercialisation of such systems is the disposability of the assay-substrate at a low cost. This work adds a new dim ...

Institution of Engineering and Technology2011

Active Posts in Deterministic Lateral Displacement Devices

Carlotta Guiducci, Kevin Keim

Using electrically connected metal-coated posts in a deterministic lateral displacement (DLD) device and applying electric fields, electrokinetics is used to tune separations, significantly decrease the critical size for separation, and increase the dynami ...

Wiley2019

Device and method for pre-term birth risk assessment

Loulia Kasem, Carlotta Guiducci, Erick Antonio Garcia Cordero, Gloria Porro

The invention relates to a vaginal fluid monitoring device embedded into a feminine sanitary pad, said device comprising a stack of the following elements: An absorbent layer (100) configured to be in proximity to, and collect, a vaginal fluid; and A biose ...

2021