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Yohan Van de Looij

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Related publications (53)

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Randomized controlled trials of non-pharmacological interventions for healthy seniors: Effects on cognitive decline, brain plasticity and activities of daily living-A 23-year scoping review

Dimitri Nestor Alice Van De Ville, Yohan Van de Looij

Little is known about the simultaneous effects of non-pharmacological interventions (NPI) on healthy older adults ' behavior and brain plasticity, as measured by psychometric instruments and magnetic resonance imaging (MRI). The purpose of this scoping rev ...

Cell Press2024

Genetic and microstructural differences in the cortical plate of gyri and sulci during gyrification in fetal sheep

Yohan Van de Looij

Gyrification of the cerebral cortex is a developmentally important process, but the mechanisms that drive cortical folding are not fully known. Theories propose that changes within the cortical plate (CP) cause gyrification, yet differences between the CP ...

2020

Glutathione deficit affects the integrity and function of the fimbria/fornix and anterior commissure in mice: relevance for schizophrenia

João Miguel das Neves Duarte, Rolf Gruetter, Yohan Van de Looij, Alberto Corcoba

BACKGROUND: Structural anomalies of white matter (WM) are found in various brain regions of patients with schizophrenia, bipolar and other psychiatric disorders, but the causes at cellular and molecular levels remain unclear. Oxidative stress and redox dys ...

Oxford Univ Press2016

High-field diffusion tensor imaging characterization of cerebral white matter injury in lipopolysaccharide-exposed fetal sheep

Yohan Van de Looij, François Lazeyras

BACKGROUND: In gyrencephalic species such as sheep, precise anatomical and microstructural characterization of the consequences of fetal inflammation remains scarce. The goal of this study was to characterize changes in white matter (WM) structure using ad ...

Lippincott, Williams & Wilkins2012

Pharmacokinetics and biodistribution study of self-assembled Gd-micelles demonstrating blood-pool contrast enhancement for MRI

Lothar Helm, Yohan Van de Looij

Magnetic resonance angiography (MRA) requires the use of contrast agents (CAs) to enable accurate diagnosis. There are currently no CAs on the market with appropriate pharmacokinetic (PK) parameters, namely long persistence in the blood, that can be easily ...

2019

Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep

Yohan Van de Looij, François Lazeyras

Preterm infants exhibit chronic deficits in white matter (WM) and cortical maturation. Although fetal infection/inflammation may contribute to WM pathology, the factors contributing to cortical changes are largely unknown. We examined the effect of fetal l ...

2011

Diffusion Tensor Echo Planar Imaging Using Surface Coil Transceiver with a Semiadiabatic RF Pulse Sequence at 14.1T

Rolf Gruetter, Yohan Van de Looij, Nicolas Kunz

Diffusion magnetic resonance studies of the brain are typically performed using volume coils. Although in human brain this leads to a near optimal filling factor, studies of rodent brain must contend with the fact that only a fraction of the head volume ca ...

Wiley-Blackwell2011

Experimental cerebral palsy causes microstructural brain damage in areas associated to motor deficits but no spatial memory impairments in the developing rat

Yohan Van de Looij

Introduction: Cerebral palsy (CP) is the major cause of motor and cognitive impairments during childhood. CP can result from direct or indirect structural injury to the developing brain. In this study, we aimed to describe brain damage and behavioural alte ...

ELSEVIER2021

Assessment Of Cerebral Osmotic Regulation In A Rat Model Of Biliary Cirrhosis Using MR Spectroscopy

Rolf Gruetter, Cristina Ramona Cudalbu Moldovan, Yohan Van de Looij, Nicolas Kunz

Elsevier2012

Effects of Lactoferrin on altered brain metabolism in pup rats after prenatal exposure to Dexamethasone

Rolf Gruetter, Yohan Van de Looij

2010

In vivo longitudinal 1H Spectroscopic Imaging and Diffusion Tensor Imaging studies at 9.4T in a rat model of chronic liver failure

Rolf Gruetter, Cristina Ramona Cudalbu Moldovan, Yohan Van de Looij, Nicolas Kunz

2012

Systemic inflammation disrupts the developmental program of white matter

Yohan Van de Looij

Perinatal inflammation is a major risk factor for neurological deficits in preterm infants. Several experimental studies have shown that systemic inflammation can alter the programming of the developing brain. However, these studies do not offer detailed p ...

2011

Effects of the cumulative exposure to Lypopolysaccharide and Hyperoxia on the developing rat brain assessed by high-field diffusion tensor imaging

Rolf Gruetter, Yohan Van de Looij

2010

Impaired White Matter Integrity in Fornix and Anterior Commissure in a Schizophrenia Mouse Model of Redox Dysregulation

Rolf Gruetter, João Miguel das Neves Duarte, Yohan Van de Looij, Alberto Corcoba

Elsevier Science Inc2014

Hindered or restricted predominance of the diffusion weighted signal function of the diffusion time at ultra-high magnetic field

Rolf Gruetter, Yohan Van de Looij, Nicolas Kunz

2011

Increased neuronal oxytocin via chemogenetic modulation positively affects microglial reactivity and brain development in a mouse model of neonatal inflammation

Yohan Van de Looij

Wiley2023

Magnetic Resonance Spectroscopy and Imaging at 9.4T in P4 rat pup brain following cerebral hypoxia-ischemia

Rolf Gruetter, Yohan Van de Looij, Nicolas Kunz

2008

Advanced magnetic resonance spectroscopy and imaging techniques applied to brain development and animal models of perinatal injury

Yohan Van de Looij

Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) are widely used in the field of brain development and perinatal brain injury. Due to technical progress the magnetic field strength (B0) of MR systems has continuously increased, fa ...

Elsevier2015

White matter changes in lipopolysaccharide (LPS) treated fetal sheep measured by high field diffusion tensor imaging (DTI)

Rolf Gruetter, Yohan Van de Looij, François Lazeyras

2008

High‐field diffusion tensor imaging characterization of cerebral white matter injury in LPS exposed fetal sheep

Rolf Gruetter, Yohan Van de Looij

2012