Publication

Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep

Yohan Van de Looij
2011
Journal Articles

Abstract

Preterm infants exhibit chronic deficits in white matter (WM) and cortical maturation. Although fetal infection/inflammation may contribute to WM pathology, the factors contributing to cortical changes are largely unknown. We examined the effect of fetal lipopolysaccharide (LPS) exposure on WM and cortical development as assessed by magnetic resonance imaging (MRI), electroencephalography (EEG), and histopathology in fetal sheep at preterm human equivalent age.

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Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep

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