Publications by Tamar Kohn | EPFL Graph Search

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Waterborne viruses can exhibit resistance to common water disinfectants, yet the mechanisms that allow them to tolerate disinfection are poorly understood. Here, we generated echovirus 11 (E11) with resistance to chlorine dioxide (ClO2) by experimental evo ...

Pharmaceuticals are substances designed to have a biological effect in humans. Their presence in the environment, especially in surface waters, is of increasing concern because of their potential risk to non-target species. A large number of pharmaceutical ...

Differentiated primary human respiratory epithelial cells grown at air-liquid interface have become a widely used cell culture model of the human conducting airways. These cultures contain secretory cells such as goblet and club cells, which produce and se ...

Container-based sanitation (CBS) within a comprehensive service system value chain offers a low-cost sanitation option with potential for revenue generation, but may increase microbial health risks to sanitation service workers. This study assessed occupat ...

The continuing emergence of SARS-CoV-2 variants of concern and variants of interest emphasizes the need for early detection and epidemiological surveillance of novel variants. We used genomic sequencing of 122 wastewater samples from three locations in Swi ...

Wastewater-based epidemiology (WBE) has emerged as an effective tool for monitoring SARS-CoV-2 dynamics during the COVID-19 pandemic. Here, we add a spatial component to WBE and use it to investigate SARS-CoV-2 spread in the canton of Ticino during the ons ...

The susceptibility of waterborne viruses to disinfection is known to vary between viruses and even between closely related strains, yet the extent of this variation is not known. Here, different enteroviruses (six strains of coxsackievirus B5, two strains ...

This paper assesses the inactivation performance and mechanisms in urine nitrification reactors using bacteria and bacteriophages as surrogates for human pathogens. Two parallel continuous-flow moving bed biofilm reactors (MBBRs) were operated over a two-m ...

SARS-CoV-2, the causative agent of COVID-19, is predominantly transmitted by respiratory aerosol and contaminated surfaces. Recent studies demonstrated that aerosols can become acidic, and acidification has been proposed as decontamination method. Here, we ...

Durch Wasser übertragene, infektiöse Humanviren sind oft im Rohwasser präsent. Bereits die Ingestion einer kleinen Anzahl solcher Viren kann diverse Krankheiten wie Gastroenteritis und Atemwegserkrankungen oder Hepatitis auslösen. Es ist also wichtig, Vire ...

Peptide-based chemicals are promising for numerous applications including home and personal care and medical treatments. To better understand and control the environmental fate of peptide-based chemicals, in-depth knowledge on the specificity of wastewater ...

Ozone is an effective disinfectant against all types of waterborne pathogens. However, accurate and quantitative kinetic data regarding virus inactivation by ozone is scarce, due to the experimental challenges associated with the high reactivity of ozone t ...

Sunlight is known to be a pertinent factor governing the infectivity of waterborne viruses in the environment. Sunlight inactivates viruses via endogenous inactivation (promoted by absorption of UVB sunlight by the virus) and exogenous processes (promoted ...

This study investigates the mechanisms underlying the deviation from Chick-Watson kinetics, namely a tailing curve, during the disinfection of viruses by chlorine dioxide (ClO2). Tailing has been previously reported, but is typically attributed to the deca ...

Powdered activated carbon (PAC) is increasingly used as tertiary treatment for the removal of trace organic contaminants (TrOCs) from wastewater (WW). To enhance the sorption kinetics and capacity, the PAC particles can be milled down to super fine powdere ...

The frequent contact people have with liquids containing pathogenic microorganisms provides opportunities for disease transmission. In this work, we quantified the transfer of bacteria—using E. coli as a model- from liquid to skin, estimated liquid retenti ...

Human urine can be processed into market-attractive fertilizers like struvite; however, concerns regarding the microbial safety of such products remain. The present study evaluated the inactivation of in situ heterotrophs, total bacteria as observed by flo ...

Enteroviruses are ubiquitous contaminants of surface waters, yet their fate in presence of microbial congeners is poorly understood. In this work, we investigated the inactivation of Echovirus-11 (E11) and Coxsackievirus-A9 (CVA9) by bacteria isolated from ...

Advanced oxidation processes (AOPs) have emerged as a promising alternative to conventional disinfection methods to control microbial water quality, yet little is known about the fate of viruses in such processes. In this study, we investigated the fate of ...

Drinking waters are treated for enteric virus via a number of disinfection techniques including chemical oxidants, irradiation, and heat, however the inactivation mechanisms during disinfection remain elusive. Due to the fact that a number of significant w ...

Tamar Kohn

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Resistance of echovirus 11 to ClO2 is associated with enhanced host receptor use, altered entry routes and high fitness

Occurrence and fate of micropollutants in the Vidy Bay of Lake Geneva, part I: Priority list for environmental risk assessment of pharmaceuticals

Comparative characterization of bronchial and nasal mucus reveals key determinants of influenza A virus inhibition

Health risks for sanitation service workers along a container-based urine collection system and resource recovery value chain

Early detection and surveillance of SARS-CoV-2 genomic variants in wastewater using COJAC

Wastewater Reveals the Spatiotemporal Spread of SARS-CoV-2 in the Canton of Ticino (Switzerland) during the Onset of the COVID-19 Pandemic

Variability in Disinfection Resistance between Currently Circulating Enterovirus B Serotypes and Strains

Inactivation kinetics and mechanisms of viral and bacterial pathogen surrogates during urine nitrification

Inactivation of SARS-CoV-2 at acidic pH is driven by partial unfolding of spike

Inaktivierung von Viren im Wasser

Conserved specificity of extracellular wastewater peptidases revealed by multiplex substrate profiling by mass spectrometry

Kinetics of inactivation of waterborne enteric viruses by ozone

A modeling approach to estimate the solar disinfection of viral indicator organisms in waste stabilization ponds and surface waters

On the cause of the tailing phenomenon during virus disinfection by chlorine dioxide

Removal of trace organic contaminants from wastewater by superfine powdered activated carbon (SPAC) is neither affected by SPAC dispersal nor coagulation

Retention of E. coli and water on the skin after liquid contact

Bacteria inactivation during the drying of struvite fertilizers produced from stored urine

Bacterial matrix metalloproteases and serine proteases contribute to the extra-host inactivation of enteroviruses in lake water

Virus removal and inactivation by iron (hydr)oxide-mediated Fenton-like processes under sunlight and in the dark

Virus disinfection mechanisms: the role of virus composition, structure, and function