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Tamar Kohn

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Related publications (102)

Direct photolysis of human metabolites of the antibiotic sulfamethoxazole: Evidence for abiotic back-transformation

Florence Bonvin, Julien Omlin, Tamar Kohn, Rebecca Rutler, Timothy Strathmann

The presence of potentially persistent and bioactive human metabolites in surface waters gives rise to concern; yet little is known to date about the environmental fate of these compounds. This work investigates the direct photolysis of human metabolites o ...

Amer Chemical Soc2013

Micropollutant dynamics in Vidy Bay - A coupled hydrodynamic-photolysis model to assess the spatial extent of ecotoxicological risk

Florence Bonvin, David Andrew Barry, Tamar Kohn, Amir Mehdi Razmi

The direct discharge of effluent wastewater into Vidy Bay (Lake Geneva) results in the formation of an effluent plume with locally high concentrations of wastewater-derived micropollutants. The micropollutant hotspots above the wastewater outfall present a ...

Amer Chemical Soc2013

Photoinactivation of virus on iron-oxide coated sand: enhancing inactivation in sunlit waters

Loïc Decrey, Tamar Kohn, Brian Pecson

Adsorption onto iron oxides can enhance the removal of waterborne viruses in constructed wetlands and soils. If reversible adsorption is not coupled with inactivation, however, infective viruses may be released when changes in solution conditions cause des ...

Elsevier2012

Virus disinfection mechanisms: the role of virus composition, structure, and function

Tamar Kohn, Krista Rule Wigginton

Drinking waters are treated for enteric virus via a number of disinfection techniques including chemical oxidants, irradiation, and heat, however the inactivation mechanisms during disinfection remain elusive. Due to the fact that a number of significant w ...

Elsevier Sci Ltd2012

Virus inactivation mechanisms: impact of disinfectants on virus function and structural integrity

Anne Thérèse Sigstam, Tamar Kohn, Brian Pecson, Krista Rule Wigginton, Franziska Sara Bosshard

Oxidative processes are often harnessed as tools for pathogen disinfection. Although the pathways responsible for bacterial inactivation with various biocides are fairly well understood, virus inactivation mechanisms are often contradictory or equivocal. I ...

Amer Chemical Soc2012

Inactivation and tailing during UV254 disinfection of viruses: contributions of viral aggregation, light shielding within viral aggregates and recombination

Michael Jon Mattle, Tamar Kohn

UV disinfection of viruses frequently leads to tailing after an initial exponential decay. Aggregation, light shielding, recombination or resistant virus sub-populations were proposed as explanations; however, none of these options has conclusively been de ...

Amer Chemical Soc2012

Pharmaceuticals and their human metabolites in Lake Geneva: occurrence, fate and ecotoxicological relevance

Florence Bonvin, Tamar Kohn, Rebecca Rutler

This study assesses the presence, fate and effects of five environmentally relevant pharmaceuticals and eight of their corresponding human metabolites in Lake Geneva. Over a 10-month period, lake samples were taken at various depths and locations in the Vi ...

2012

Inactivation of bacteriophage MS2 with potassium ferrate(VI)

Anne Thérèse Sigstam, Tamar Kohn, Timothy Strathmann

Ferrate [Fe(VI); FeO42-] is an emerging oxidizing agent capable of controlling chemical and microbial water contaminants. Here, inactivation of MS2 coliphage by Fe(VI) was examined. The inactivation kinetics observed in individual batch experiments was wel ...

Amer Chemical Soc2012

UV radiation induces genome-mediated, site-specific cleavage in viral protein

Hisham Ben Hamidane, Anne Thérèse Sigstam, Michele Cascella, Tamar Kohn, Yury Tsybin, Laure Menin, Krista Rule Wigginton

Much research has been dedicated to understanding the molecular basis of UV damage to biomolecules, yet many questions remain regarding the specific pathways involved. Here we describe a genome-mediated mechanism that causes sitespecific virus protein clea ...

2012

Spatial and temporal presence of a wastewater-derived micropollutant plume in Lake Geneva

Florence Bonvin, Tamar Kohn, Rebecca Rutler

This study discusses the occurrence and environmental risk associated with a micropollutant plume originating from the direct discharge of treated wastewater into the Vidy Bay of Lake Geneva, Switzerland. The temporal variations and spatial extent of the p ...

2011

A framework for using quantitative PCR as a non-culture based method to estimate virus infectivity

Tamar Kohn, Brian Pecson, Martin Ackermann

Measuring the efficiency of virus disinfection with quantitative PCR (qPCR) has been criticized as inadequate due to the production of false-positive signals. Such a claim, however, presupposes an understanding of the theoretical qPCR response. Many studie ...

2011

Fate of the pathogen indicators phage phiX174 and Ascaris suum eggs during the production of struvite fertilizer from source-separated urine

Loïc Decrey, Tamar Kohn, Brian Pecson, Kai Udert

Human urine has the potential to be a sustainable, locally and continuously available source of nutrients for agriculture. Phosphate can be efficiently recovered from human urine in the form of the mineral struvite (MgNH4PO4•6H2O). However, struvite format ...

Elsevier2011

Role of Temperature and Suwannee River Natural Organic Matter on Inactivation Kinetics of Rotavirus and Bacteriophage MS2 by Solar Irradiation

Tamar Kohn

Although the sunlight mediated inactivation of viruses has been recognized as an important process that controls surface water quality, the mechanisms of virus inactivation by sunlight are not yet clearly understood. We investigated the synergistic role of ...

2011

Impact of virus aggregation on inactivation by peracetic acid and implications for other disinfectants

Benoît Crouzy, Michael Jon Mattle, Tamar Kohn, Paolo Perona, Moritz Brennecke, Krista Rule Wigginton

Viruses in wastewater and natural environments are often present as aggregates. The disinfectant dose required for their inactivation, however, is typically determined with dispersed viruses. This study investigates how aggregation affects virus inactivati ...

2011

Pharmaceuticals and Personal Care Products (PPCPs) in Effluent Matrices: A Survey of Transformation and Removal during Wastewater Treatment and Implications for Wastewater Management

Tamar Kohn

Pharmaceuticals and personal care products (PPCPs) represent pollutants of emerging concern, originating in surface and drinking waters largely from their persistence in wastewater effluent. Accordingly, a wealth of recent investigations has examined PPCP ...

Royal Society of Chemistry2010

Occurrence and fate of micropollutants in the Vidy Bay of Lake Geneva, part I: Priority list for environmental risk assessment of pharmaceuticals

Chiara Perazzolo, Tamar Kohn

Pharmaceuticals are substances designed to have a biological effect in humans. Their presence in the environment, especially in surface waters, is of increasing concern because of their potential risk to non-target species. A large number of pharmaceutical ...

Society of Environmental Toxicology and Chemistry Press2010

Oxidation of Virus Proteins during UV(254) and Singlet Oxygen Mediated Inactivation

Tamar Kohn, Jonathan Paz Montoya, Krista Rule Wigginton

Despite the widespread use of UV254 irradiation and solar disinfection for water treatment, little is known about the photochemical pathways that lead to virus inactivation by these treatments. The goal of this study was to identify reactions that occur in ...

2010

Reactivity of Alkyl Polyhalides toward Granular Iron: Development of QSARs and Reactivity Cross Correlations for Reductive Dehalogenation

Tamar Kohn

Attempts to develop quantitative structure-activity relationships (QSARs) for reductive dehalogenation have been hindered by the unavailability of high quality predictor variables, have included relatively few compounds, and on occasion have relied on data ...

2010

Occurrence and fate of micropollutants in the Vidy Bay of Lake Geneva, part II: Micropollutant removal between wastewater and raw drinking water

Frédéric Bonvin, Luiz Felippe De Alencastro, Dominique Grandjean, Chiara Perazzolo, Florence Bonvin, Tamar Kohn

The occurrence and removal of 58 pharmaceuticals, endocrine disruptors, corrosion inhibitors, biocides, and pesticides, were assessed in the wastewater treatment plant (WWTP) of the city of Lausanne, Switzerland, as well as in the effluent-receiving water ...

Society of Environmental Toxicology and Chemistry Press2010

Inactivation of MS2 coliphage in Fenton and Fenton-like systems: role of transition metals, hydrogen peroxide and sunlight

Andrzej Sienkiewicz, Tamar Kohn, Jessica Ivana Nieto Juarez

The inactivation of coliphage MS2 by iron- and copper-catalyzed Fenton systems was studied to assess the importance of this process for virus inactivation in natural systems and during water treatment by advanced oxidation processes. The influence of H2O2 ...

American Chemical Society2010

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