Aurélien Bornet

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Related publications (48)

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Micromolar Concentration Affinity Study on a Benchtop NMR Spectrometer with Secondary 13C Labeled Hyperpolarized Ligands

Aurélien Bornet

Benchtop NMR is becoming an increasingly important tool, sometimes providing a simple and low-cost alternative to high-field NMR. The Achilles heel of NMR and even more critically of benchtop NMR is its limited sensitivity. However, when combined with hype ...

AMER CHEMICAL SOC2025

Dynamic Nuclear Polarization of Long-Lived Nuclear Spin States in Methyl Groups

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Basile Vuichoud, Arthur César Pinon, Gabriele Stevanato, Daniele Mammoli

We have induced hyperpolarized long-lived states in compounds containing C-13-bearing methyl groups by dynamic nuclear polarization (DNP) at cryogenic temperatures, followed by dissolution with a warm solvent. The hyper polarized methyl long-lived states g ...

Amer Chemical Soc2017

Microwave-gated dynamic nuclear polarization

Geoffrey Bodenhausen, David Lyndon Emsley, Sami Jannin, Aurélien Bornet, Arthur César Pinon, Xiao Ji

Dissolution dynamic nuclear polarization (D-DNP) has become a method of choice to enhance signals in nuclear magnetic resonance (NMR). Recently, we have proposed to combine cross-polarization (CP) with D-DNP to provide high polarization P(C-13) in short bu ...

Royal Society of Chemistry2016

Boosting Dissolution Dynamic Nuclear Polarization by Cross Polarization

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Angel Joaquin Perez Linde

The efficiency of dissolution dynamic nuclear polarization can be boosted by Hartmann-Hahn cross polarization at temperatures near 1.2 K. This enables high throughput of hyperpolarized solutions with substantial gains in buildup times and polarization leve ...

Amer Chemical Soc2013

Crowding reveals fundamental differences in local vs. global processing in humans and machines

Michael Herzog, Aurélien Bornet, Adrien Christophe Doerig, Oh-Hyeon Choung

Feedforward Convolutional Neural Networks (ffCNNs) have become state-of-the-art models both in computer vision and neuroscience. However, human-like performance of ffCNNs does not necessarily imply human-like computations. Previous studies have suggested t ...

2020

Operando Monitoring of Delignification Processes Using 2D 1H-13C HSQC NMR

Jeremy Luterbacher, Aurélien Bornet, Songlan Sun, Claire Laura Marion Charline Bourmaud

American Chemical Society (ACS)2025

Hyperpolarized NMR of plant and cancer cell extracts at natural abundance

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Jonas Milani, Basile Vuichoud

Natural abundance C-13 NMR spectra of biological extracts are recorded in a single scan provided that the samples are hyperpolarized by dissolution dynamic nuclear polarization combined with cross polarization. Heteronuclear 2D correlation spectra of hyper ...

Royal Society of Chemistry2015

Toward Quantitative Measurements of Enzyme Kinetics by Dissolution Dynamic Nuclear Polarization

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Jonas Milani

Dissolution dynamic nuclear polarization (D-DNP) experiments enabled us to study the kinetics of the enzymatic phosphorylation reaction of glucose to form glucose-6-phosphate (G6P) by hexokinase (HK), with or without the presence of an excess of G6P, which ...

2014