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Related publications (122)

Page 4 of 7

gamma-aminobutyric acid measurement in the human brain at 7 T: Short echo-time or Mescher-Garwood editing

Lijing Xin, Songi Lim

The purposes of the current study were to introduce a Mescher-Garwood (MEGA) semi-adiabatic spin-echo full-intensity localization (MEGA-sSPECIAL) sequence with macromolecule (MM) subtraction and to compare the test-retest reproducibility of gamma-aminobuty ...

WILEY2022

Redox Dysregulation, Myelination Deficit and Dysconnectivity in Schizophrenia: A Translational Study in First Episode Patients and Experimental Models

Rolf Gruetter, Lijing Xin, Patric Hagmann, Alessandra Griffa

ELSEVIER SCIENCE INC2021

Redox Dysregulation, Myelination Deficit and Dysconnectivity in Schizophrenia: A Translational Study in First Episode Patients and Experimental Models

Rolf Gruetter, Lijing Xin, Patric Hagmann, Alessandra Griffa

ELSEVIER SCIENCE INC2020

Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans

Rolf Gruetter, Lijing Xin, Özlem Ipek, Maya Shevlyakova

The brain requires a large amount of energy, mostly derived from the metabolism of glucose, which decreases substantially with age and neurological diseases. While mounting evidence in model organisms illustrates the central role of brain nicotinamide aden ...

FRONTIERS MEDIA SA2020

Neuronal energy metabolism in the mouse brain measured by H-1-[C-13] MRS at 14.1T under [3-C-13]-Lactate infusion: a feasibility study

Lijing Xin, Hongxia Lei, Bernard Lanz, Nicolas Kunz

SAGE PUBLICATIONS INC2019

In vivo measurement of glycine with short echo-time H-1 MRS in human brain at 7 T

Rolf Gruetter, Lijing Xin, Wietske Van der Zwaag, Gunnar Krüger, Giulio Gambarota

To determine whether glycine can be measured at 7 T in human brain with H-1 magnetic resonance spectroscopy (MRS). ...

2009

Genetic Association with Prefrontal Glutathione Deficit: A 3T 1H MRS Study in Early Psychosis

Rolf Gruetter, Lijing Xin, Huanxiang Lu

Elsevier Science Inc2014

A double-quadrature radiofrequency coil design for proton-decoupled carbon-13 magnetic resonance spectroscopy in humans at 7T

Rolf Gruetter, Lijing Xin, Eulalia Serés Roig, Guillaume Donati, Özlem Ipek

Purpose Carbon-13 magnetic resonance spectroscopy (13C-MRS) is challenging because of the inherent low sensitivity of 13C detection and the need for radiofrequency transmission at the 1H frequency while receiving the 13C signal, the latter requiring electr ...

Wiley-Blackwell2015

Quantification of brain glycogen concentration and turnover through localized C-13 NMR of both the C1 and C6 resonances

Rolf Gruetter, Lijing Xin, Ruud van Heeswijk

We have recently shown that at isotopic steady state C-13 NMR can provide a direct measurement of glycogen concentration changes, but that the turnover of glycogen was not accessible with this protocol. The aim of the present study was to design, implement ...

Wiley-Blackwell2010

Are glutamate and lactate increases ubiquitous to physiological activation? A 1H functional MR spectroscopy study during motor activation in human brain at 7Tesla

Rolf Gruetter, Lijing Xin, Benoît Schaller

Recent studies at high field (7 Tesla) have reported small metabolite changes, in particular lactate and glutamate (below 0.3 μmol/g) during visual stimulation. These studies have been limited to the visual cortex because of its high energy metabolism and ...

Elsevier2014

Neurometabolism in Grey Matter of Children With Chronic Liver Disease or Portosystemic Shunting: A 1H-MRS Study at 7T

Cristina Ramona Cudalbu Moldovan, Lijing Xin

LIPPINCOTT WILLIAMS & WILKINS2019

Metabolic And Transcriptional Profiles Of Gbm Invasion: Comparison Of Patients And Paired Patient Derived Xenografts Using1H Magnetic Resonance Spectroscopy And Imaging (7T And 14T) And Rna-Sequencing

Rolf Gruetter, Cristina Ramona Cudalbu Moldovan, Lijing Xin, Mario Gaetano Lepore, Marta Lai

OXFORD UNIV PRESS INC2018

Quantification of in vivo short echo-time proton magnetic resonance spectra at 14.1 T using two different approaches of modelling the macromolecule spectrum

Rolf Gruetter, Cristina Ramona Cudalbu Moldovan, Lijing Xin

Reliable quantification of the macromolecule signals in short echo-time H-1 MRS spectra is particularly important at high magnetic fields for an accurate quantification of metabolite concentrations (the neurochemical profile) due to effectively increased s ...

IOP Publishing2009

Twisted pair transmission line coil - a flexible, self-decoupled and robust element for 7 T MRI

Lijing Xin, Daniel Wenz, Ying Xiao

Objective: This study evaluates the performance of a twisted pair transmission line coil as a transceive element for 7 T MRI in terms of physical flexibility, robustness to shape deformations, and interelement decoupling. Methods: Each coil element was cre ...

Elsevier Science Inc2024

Neurochemical characteristics of pathological tissues in epilepsy: A preliminary 1H MR spectroscopy study at 7 T

Lijing Xin

Background and purpose: This study aims to evaluate the neurochemical characteristics of pathological tissues by 1H magnetic resonance spectroscopy (MRS) in patient with pharmaco-resistant focal epilepsy at 7 T. Methods: Thirteen patients with drug-resista ...

2025

Profiling Glutamate And D-Serine Pathways In Treatment Resistant Early Psychosis Patients

Lijing Xin

OXFORD UNIV PRESS2020

Metabolite concentration changes during increase of the BOLD signal in the human visual cortex: a functional magnetic resonance spectroscopy study at 7T

Rolf Gruetter, Lijing Xin, Wietske Van der Zwaag, Yohan Boillat

Sage Publications Inc2017

Comparison of two approaches to model the macromolecule spectrum for the quantification of short TE H-1 MRS spectra

Rolf Gruetter, Cristina Ramona Cudalbu Moldovan, Lijing Xin

Accurate assessment of the macromolecule contributions in short echo-time proton MRS spectra is important for a reliable quantification of the neurochemical profile. The aim of the present study was to assess two approaches based on using LCModel, which ta ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2008

Clinical Neuroimaging Using 7 T MRI: Challenges and Prospects

Rolf Gruetter, Lijing Xin, François Lazeyras, Özlem Ipek

The aim of this article is to illustrate the principal challenges, from the medical and technical point of view, associated with the use of ultrahigh field (UHF) scanners in the clinical setting and to present available solutions to circumvent these limita ...

2018

N-Acetyl-Cysteine In A Doubleblind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment In Early Psychosis

Rolf Gruetter, Lijing Xin

Oxford Univ Press2017