Martinus Adela Maria Gijs

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We present three-dimensional (3D) micromixers realized in a monolithic glass substrate using a simple oblique powder-blasting microfabrication method and a single photosensitive elastomeric mask. The mixer topology consists of a curved microchannel that incorporates a series of nozzle-diffuser elements buried inside the glass substrate. The strongly varying microfluidic cross-section of these elements and multiple channel bends result in the generation of multiple vortices. This results in achieving a high

We demonstrate the drastic improvement in absorbance and photoluminescence (UV-PL) of CdSe nanocrystals (NCs) upon adding both a carboxylic acid and an amine ligand to the cadmium acetate green chemistry source. We combined carboxylate complexes of lauric ...

We introduce a new and simple microfluidic sorting device based on adjustable filter structures that can be easily tuned by external pressure for a specific size-dependent C. elegans worm sorting experiment. A single device can be used for selecting and so ...

We present a multiplexed and automated microfluidic platform for phenotyping of C. elegans during their full lifespan and at high-throughput. We used the fluorescent hsp-6::gfp strain of worms and performed experiments to observe the effect of four differe ...

Miniaturized system for bioanalysis have been constantly gaining importance and interest within the recent years. The reduction of sample consumption and reaction time are some of the major advantages of such lab-on-a-chip applications. One of the greatest ...

We performed a direct immunoassay inside a microfluidic channel on patterned streptavidin-coated beads, which captured fluorescently-labeled biotin target molecules from a continuous flow. We arranged the beads in a dot array at the bottom of the channel a ...

We present the microfabrication and characterisation of a ball valve micropump in glass, which is magnetically actuated using the sinusoidal current of an external electromagnet. We employ the use of a simple powder blasting technology for microstructuring ...

We present oblique powder blasting as a three-dimensional micromachining technology for brittle materials. Powder blasting is a microfabrication process, based on the use of a pressurised air beam containing eroding Al2O3 particles. By varying the angle of incidence of the incoming particles to a substrate, covered by a mask, one can exploit the oblique slopes of micropatterned holes and mask underetching phenomena to generate new options for three-dimensional microstructuring. We have identified and quanti

Parallel heat flux calculations at the JET divertor have been based on the assumption that all incoming heat is due to the projection of the heat flux parallel to the magnetic line, q, plus a constant background. This simplification led to inconsistencies ...

The invention discloses a microfluidic device for the culture, selection and/or analysis of sample organisms such as nematodes, as well as for other biological entities such as for instance animal embryos. The device features reservoirs, culture chambers a ...

This review describes recent advances in the handling and manipulation of magnetic particles in microfluidic systems. Starting from the properties of magnetic nanoparticles and microparticles, their use in magnetic separation, immuno-assays, magnetic resonance imaging, drug delivery, and hyperthermia is discussed. We then focus on new developments in magnetic manipulation, separation, transport, and detection of magnetic microparticles and nanoparticles in microfluidic systems, pointing out the advantages a

Separation of functional magnetic particles or magnetically labeled entities is a key feature for bioanalytical or biomedical applications and therefore also an important component of lab-on-a-chip devices for biological applications. We present a novel in ...

We have developed a flexible-substrate-based three-axial force sensor, composed of finger-shaped electrode capacitors, whose operation is based on the measurement of a capacitance change induced upon applying a three-axial load. The electrode design suppor ...

Simultaneous washing and concentration of functionalized magnetic beads in a complex sample solution was demonstrated by applying a rotational magnetic actuation system to a microfluidic chip under continuous flow conditions. The rotation of periodically a ...

We report the continuous growth of spherical assemblies of silica and titania nanoparticles, which were pre-activated to produce hydroxyl/ peroxy groups on their surface, by flowing a colloid-in-dioctyl phthalate emulsion into a polydimethylsiloxane microf ...

Martinus Adela Maria Gijs

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Three-dimensional mixers with non-planar microchannels in a monolithic glass substrate using oblique powder blasting

Synergistic effect of carboxylic and amine ligands on the synthesis of CdSe nanocrystals

Super-Resolution Biological Microscopy Using Virtual Imaging by a Microsphere Nanoscope

Size-dependent sorting of C. elegans nematodes through an adjustable microfluidic filter structure

A microfluidic platform for automated phenotyping during full lifespan of Caenorhabditis elegans at high-throughput

CMOS and 3D Printing for NMR Spectroscopy at the Single Embryo Scale

On-chip antibody handling and colorimetric detection in a magnetic droplet manipulation system

Study of Spatio-Temporal Immunofluorescence on Bead Patterns in a Microfluidic Channel

A ball valve micropump in glass fabricated by powder blasting

Oblique Powder Blasting for Three-dimensional Micromachining of Brittle Materials

An improved model for the accurate calculation of parallel heat fluxes at the JET bulk tungsten outer divertor

Use of a Parylene-C bonding layer fluorescence as reference for on-chip imaging and detection applications

Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation (vol 22, pg 560, 2022)

Microfluidic device, system and method for the study of organisms

Magnetic bead handling on-chip: new opportunities for analytical applications

Magnetic particle dosing and size separation in a microfluidic channel

Polymer-based flexible capacitive sensor for three-axial force measurements

Magnetic particle dosing, release and separation in a microfluidic chip with magnetic actuation

Simultaneous sample washing and concentration using a “trapping-and-releasing” mechanism of magnetic beads on a microfluidic chip

A microfluidic process for on-chip formation of assemblies of oxide nanoparticles