Publications by Andrzej Kulik | EPFL Graph Search

Related publications (47)

E. coli Inactivation by High-Power Impulse Magnetron Sputtered (HIPIMS) Cu Surfaces

César Pulgarin, Juan Kiwi, Andrzej Kulik

This study reports HIPIMS-sputtered samples of Cu-particulate films with currents at 6 and 60 amps leading to E. coil inactivation. The Cu coverage and nanoparticle structure of the fibers is reported by TEM. Evidence is presented of redox processes in the ...

2011

Nanoscale spatially resolved infrared spectra from single microdroplets

Giovanni Dietler, Andrzej Kulik, Francesco Simone Ruggeri

Droplet microfluidics has emerged as a powerful platform allowing a large number of individual reactions to be carried out in spatially distinct microcompartments. Due to their small size, however, the spectroscopic characterisation of species encapsulated ...

Royal Society of Chemistry2014

The increase in protein contour length depends on mechanical unfolding conditions

László Forró, Andrzej Kulik

Many proteins in alive organisms have a domain structure providing them the possibility to reversible unfolding, which seems to play an essential role in those processes occurring in tissues which are controlled by mechanical cellular tension. In this work ...

2008

Assessing dystrophies and other muscle diseases at the nanometer scale by atomic force microscopy

Giovanni Dietler, Harald Brune, Andrzej Kulik, Nicolas Mermod, Guillaume Witz

Aim: Atomic force microscopy nanoindentation of myofibers was used to assess and quantitatively diagnose muscular dystrophies from human patients. Materials & methods: Myofibers were probed from fresh or frozen muscle biopsies from human dystrophic patient ...

Future Medicine2014

Model-Based Estimation of Three-Dimensional Stiffness Parameters in Photonic-Force Microscopy

Michaël Unser, Andrzej Kulik, Philippe Thévenaz, Elena Bertseva

We propose a system to characterize the 3-D diffusion properties of the probing bead trapped by a photonic-force microscope. We follow a model-based approach, where the model of the dynamics of the bead is given by the Langevin equation. Our procedure comb ...

Institute of Electrical and Electronics Engineers2010

Infrared nanospectroscopic mapping of a single metaphase chromosome

Giovanni Dietler, Andrzej Kulik, Francesco Simone Ruggeri, Ewelina Wioletta Lipiec

The integrity of the chromatin structure is essential to every process occurring within eukaryotic nuclei. However, there are no reliable tools to decipher the molecular composition of metaphase chromosomes. Here, we have applied infrared nanospectroscopy ...

Oxford University Press (OUP)2019

Probing fibronectin-antibody interactions using AFM force spectroscopy and lateral force microscopy

Andrzej Kulik, Kyumin Lee

The first experiment showing the effects of specific interaction forces using lateral force microscopy (LFM) was demonstrated for lectin-carbohydrate interactions some years ago. Such measurements are possible under the assumption that specific forces stro ...

Beilstein-Institut2015

Nanoscale resolution in infrared imaging of protein-containing lipid membranes

Giovanni Dietler, Andrzej Kulik

The precise imaging of biomolecular entities contributes to an understanding of the relationship between their structure and function. However, the resolution of conventional infrared microscopic imaging is diffraction limited and does not exceed a few mic ...

Royal Society of Chemistry2015

Diameter-Dependent Elastic Modulus Supports the Metastable-Catalyst Growth of Carbon Nanotubes

László Forró, Arnaud Magrez, Andrzej Kulik, Jin Won Seo, Kyumin Lee, Branimir Lukic

We measured the elastic modulus of individual multiwalled carbon nanotubes (MWCNTs) grown by catalytic chemical vapor deposition (CVD) over a broad diameter range (10-25 nm). Alternating current (ac) dielectrophoresis was used for efficient tube deposition ...

American Chemical Society (ACS)2007

MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation

Andrzej Kulik, Nicolas Mermod, Damien Saugy

Background: The in vivo transfer of naked plasmid DNA into organs such as muscles is commonly used to assess the expression of prophylactic or therapeutic genes in animal disease models. Results: In this study, we devised vectors allowing a tight regulatio ...

BioMed Central2013

Photocatalytic and phototoxic properties of TiO2-based nanofilaments: ESR and AFM assays

László Forró, Arnaud Magrez, Andrzej Kulik, Andrzej Sienkiewicz, Katarzyna Pierzchala

There is uncertainty in understanding of the relationship between physico-chemical parameters of nanosized titanium dioxide (nano-TiO2) and its toxicity when brought into contact with living cells. This study provides a multidisciplinary experimental insig ...

Informa Healthcare2012

Innovative transparent non-scattering TiO2 bactericide thin films inducing increased E. coli cell wall fluidity

César Pulgarin, Juan Kiwi, Lioubov Kiwi, Sami Rtimi, Andrzej Kulik, Rosendo Sanjines, Mariusz Andrzejczuk

This study presents the first account for transparent, non-scattering TiO2 films on radio-frequency (RF) plasma and ultraviolet light in the C-spectral region (UVC) pretreated polyethylene (PE). These pretreatments allow the PE to bind higher amounts of Ti ...

Elsevier Science Sa2014

Uniformly Dispersed Deposition of Colloidal Nanoparticles and Nanowires by Boiling

Jürgen Brugger, László Forró, Arnaud Magrez, Andrzej Kulik, Sylvia Jeney, Jin Won Seo, Kyumin Lee, Gerit Kulik

Uniformly dispersed deposition of various nanoparticles (gold and silver of 20?50 nm) and nanowires (ZnO and VOx) on different surfaces (Si, GaAs, mica, and steel) was obtained by boiling colloid drops on preheated substrates. Our results suggest a deposit ...

AIP American Institute of Physics2007

Correlations between adhesion hysteresis and friction at molecular scales

Andrzej Kulik, Gérard Gremaud, Robert Szoszkiewicz

Correlations between adhesion hysteresis and local friction are theoretically and experimentally investigated. The model is based on the classical theory of adhesional friction, contact mechanics, capillary hysteresis, and nanoscale roughness. Adhesion hys ...

2005

Motion of a colloidal particle in an optical trap

László Forró, Andrzej Kulik, Sylvia Jeney, Branimir Lukic

Thermal position fluctuations of a colloidal particle in an optical trap are measured with microsecond resolution using back-focal-plane interferometry. The mean-square displacement MSD(t) and power spectral density are in excellent agreement with the theo ...

2007

Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds

Andrzej Kulik, Boris Hinz, Jean-Jacques Meister, Kyumin Lee, Philippe Pittet

We have previously shown that the switch from N-cadherin to OB-cadherin expression increases intercellular adhesion between fibroblasts during their transition from a migratory to a fibrogenic phenotype. Using atomic force microscopy we here show that part ...

2008

A single-molecule stretching method for lateral and normal AFM lever calibration

Giovanni Dietler, Andrzej Kulik, Fabrizio Benedetti

A novel method for quantitative lateral force measurement (LFM) calibration has been developed. Using a single-molecule spectroscopy approach it is possible to calibrate the AFM levers for both lateral and normal spring constants with a single image scan. ...

Institute of Physics2013

Gene-mediated Restoration of Normal Myofiber Elasticity in Dystrophic Muscles

Andrzej Kulik, Nicolas Mermod, Damien Saugy

Dystrophin mediates a physical link between the cytoskeleton of muscle fibers and the extracellular matrix, and its absence leads to muscle degeneration and dystrophy. In this article, we show that the lack of dystrophin affects the elasticity of individua ...

2009

Can Dissipative Properties of Single Molecules Be Extracted from a Force Spectroscopy Experiment?

Giovanni Dietler, Andrzej Kulik, Serguei Sekatski, Fabrizio Benedetti, Dmitry Klinov

We performed dynamic force spectroscopy of single dextran and titin 127 molecules using small-amplitude and low-frequency (40-240 Hz) dithering of an atomic force microscope tip excited by a sine wave voltage fed onto the tip-carrying piezo. We show that f ...

Elsevier2016

Temperature-Dependent Elasticity of Microtubules

László Forró, Andras Kis, Andrzej Kulik, Sandor Kasas

Central to the biological function of microtubules. is their ability to modify their length which occurs by addition and removal of subunits at the ends of the polymer, both in vivo and in vitro. This dynamic behavior is strongly influenced by temperature. ...

American Chemical Society2008