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Lecture

Cardiac Mechanics: Arterial Flow Modeling

Description

This lecture covers the measurement of cardiac oxygen consumption, calculation of work and power in the left ventricle, the relationship between oxygen consumption and pressure, the tension time index, and the rate-pressure product. It also discusses the concept of ventricular and arterial elastance, optimal power output, and the 1D model of the arterial system, including equations and boundary conditions. The presentation concludes with examples of aortic stenosis, MRI modeling, and comparisons between model predictions and measurements of flow rate and pressure in various arteries.

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Instructor

Nikolaos Stergiopoulos

Education MTE, Managing the Technology Enterprise Program (2000), IMD, Lausanne Ph.D. in Biomedical Engineering & Engineering Mechanics (1990) Iowa State University, Ames, Iowa. MS in Biomedical Engineering (1987) Iowa State University, Ames, Iowa. Diploma in Mechanical Engineering (1985) National Technical University of Athens. Professional Activities 2002 - present: Professor and director of LHTC 2010 - present: Founder and director of Rheon Medical SA, Préverenges, Switzerland 2008 - present: Founder and director of Antlia S.A., PSE-C, EPFL campus, Switzerland 1998 - 2007: Founder and Scientific Director of EndoArt S.A., Lausanne, Switzerland 1996 - 2002: Assistant professor at the Biomedical Engineering Laboratory, Swiss Federal Institute of Technology, Lausanne, Switzerland. 1991 - 1996: Research Associate at Swiss Federal Institute of Technology - Lausanne 1990 - 1991: Lecturer, Iowa State University

Official source

Ontological neighbourhood

Health sciences

Cardiology: Cardiovascular disease

Related concepts (32)

Aortic stenosis

Aortic stenosis (AS or AoS) is the narrowing of the exit of the left ventricle of the heart (where the aorta begins), such that problems result. It may occur at the aortic valve as well as above and below this level. It typically gets worse over time. Symptoms often come on gradually with a decreased ability to exercise often occurring first. If heart failure, loss of consciousness, or heart related chest pain occur due to AS the outcomes are worse. Loss of consciousness typically occurs with standing or exercising.

Ventricle (heart)

A ventricle is one of two large chambers toward the bottom of the heart that collect and expel blood towards the peripheral beds within the body and lungs. The blood pumped by a ventricle is supplied by an atrium, an adjacent chamber in the upper heart that is smaller than a ventricle. Interventricular means between the ventricles (for example the interventricular septum), while intraventricular means within one ventricle (for example an intraventricular block).

Blood pressure

Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery, where it is most commonly measured. Blood pressure is usually expressed in terms of the systolic pressure (maximum pressure during one heartbeat) over diastolic pressure (minimum pressure between two heartbeats) in the cardiac cycle.

Dirichlet boundary condition

In the mathematical study of differential equations, the Dirichlet (or first-type) boundary condition is a type of boundary condition, named after Peter Gustav Lejeune Dirichlet (1805–1859). When imposed on an ordinary or a partial differential equation, it specifies the values that a solution needs to take along the boundary of the domain. In finite element method (FEM) analysis, essential or Dirichlet boundary condition is defined by weighted-integral form of a differential equation.

Robin boundary condition

In mathematics, the Robin boundary condition (ˈrɒbɪn; properly ʁɔbɛ̃), or third type boundary condition, is a type of boundary condition, named after Victor Gustave Robin (1855–1897). When imposed on an ordinary or a partial differential equation, it is a specification of a linear combination of the values of a function and the values of its derivative on the boundary of the domain. Other equivalent names in use are Fourier-type condition and radiation condition.

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