Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Graph
Search

Course

CH-332: Medicinal chemistry

Summary

Sitting at the crossroad of organic chemistry and medicine, this course outlines how an initial hit compound transitions into a lead candidate, and ultimately a drug, in the modern drug discovery world.

Note: the course is held only during 2nd half of spring semester (10 - 14 h on Fri of Week 7-14)

Lectures

Instructors

Official source

https://edu.epfl.ch/coursebook/en/medicinal-chemistry-CH-332

Moodle Page

http://go.epfl.ch/CH-332

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Summary

Note: the course is held only during 2nd half of spring semester (10 - 14 h on Fri of Week 7-14)

Lectures

Instructors

Official source

https://edu.epfl.ch/coursebook/en/medicinal-chemistry-CH-332

Moodle Page

http://go.epfl.ch/CH-332

About this result

Lectures in this course (12)

Interrogating SAR in Medical Chemistry Log in to Mediaspace to watch this video

Delves into the fundamentals of medicinal chemistry, emphasizing the interrogation of Structure-Activity Relationships (SAR) in drug design.

Identifying Drug Targets: Safety and Efficacy Log in to Mediaspace to watch this video

Delves into identifying drug targets, ensuring efficacy, and maintaining safety in medical chemistry, covering genetic tests, chirality, stereochemistry, drug resistance, and drug-likeness rules.

Pharmacokinetic & Pharmacodynamic Evaluations Log in to Mediaspace to watch this video

Covers the principles of pharmacokinetics and pharmacodynamics, including drug exposure-response relationships.

Preclinical Animal Models: Selection & Rationale Log in to Mediaspace to watch this video

Explores the selection and rationale of preclinical animal models in drug development, emphasizing the 10 to 15-year path to a marketed small-molecule drug.

Fragment-Based Drug Discovery: Concepts & Technologies Log in to Mediaspace to watch this video

Covers the concepts and technologies of fragment-based drug discovery, exploring hit identification, lead optimization, and screening methods.

Related courses (26)

BIO-212: Biological chemistry I

Biochemistry is a key discipline for the Life Sciences. Biological Chemistry I and II are two tightly interconnected courses that aim to describe and understand in molecular terms the processes that make life possible. ...

CH-317: Drug discovery and development

This course discusses the molecular basis of diseases and how drugs work. Concepts and processes employed in today's drug discovery and development are covered. The first part of the course focuses on small molecule drugs and the second one on biotherapeut ...

BIOENG-320: Synthetic biology

This advanced Bachelor/Master level course will cover fundamentals and approaches at the interface of biology, chemistry, engineering and computer science for diverse fields of synthetic biology. This class requires critical and analytical thinking at the ...

ENG-436: Food biotechnology

The course will deliver basic knowledge on the principles of food fermentation and enzyme technology. The course will also present benefits that food biotechnology can bring in terms of Nutrition & Health and Sustainability. ...

BIOENG-399: Immunoengineering

Immunoengineering is an emerging field where engineering principles are grounded in immunology. This course provides students a broad overview of how engineering approaches can be utilized to study immunology, model immune systems, modulate immune response ...