Ayberk OzkirliDr. Ayberk Ozkirli is a vision neuroscientist whose research investigates how spatiotemporal context influences visual perception.He completed his PhD in Neuroscience at the Laboratory of Psychophysics at EPFL in 2025, under the supervision of Prof. Michael Herzog and Prof. David Pascucci. He holds an M.Sc. in Bioengineering from EPFL (Switzerland) and a B.Sc. in Electrical and Electronics Engineering from Bilkent University (Turkey).His expertise spans neuroimaging, statistics, experimental design, neural
Friedhelm Christoph HummelExpertise
Stroke recovery Healthy Aging Motor Control Motor Learning Cognitive Control Neuroplasticity Non-invasive Brain Stimulation Structural and functional Neuroimaging Connectivity
Postal Address Campus Biotech
Defitech Chair of Clinical Neuroengineering Brain Mind Institute, SV Neuro X Institute, Swiss Federal Institute of Technology EPFL Campus Biotech Rm H4.3.132.084, 9, Chemin des Mines 1202 Geneva
Teaching & PhD PhD Students Maria Ploumitsakou, Simona Losacco, Fabienne Windel, Andrea Protani, Sta
Henry MarkramHenry Markram started a dual scientific and medical career at the University of Cape Town, in South Africa. His scientific work in the 80s revealed the polymodal receptive fields of pontomedullary reticular formation neurons in vivo and how acetylcholine re-organized these sensory maps.
He moved to Israel in 1988 and obtained his PhD at the Weizmann Institute where he discovered a link between acetylcholine and memory mechanisms by being the first to show that acetylcholine modulates the NMDA receptor in vitro studies, and thereby gates which synapses can undergo synaptic plasticity. He was also the first to characterize the electrical and anatomical properties of the cholinergic neurons in the medial septum diagonal band.
He carried out a first postdoctoral study as a Fulbright Scholar at the NIH, on the biophysics of ion channels on synaptic vesicles using sub-fractionation methods to isolate synaptic vesicles and patch-clamp recordings to characterize the ion channels. He carried out a second postdoctoral study at the Max Planck Institute, as a Minerva Fellow, where he discovered that individual action potentials propagating back into dendrites also cause pulsed influx of Ca2 into the dendrites and found that sub-threshold activity could also activated a low threshold Ca2 channel. He developed a model to show how different types of electrical activities can divert Ca2 to activate different intracellular targets depending on the speed of Ca2 influx an insight that helps explain how Ca2 acts as a universal second messenger. His most well known discovery is that of the millisecond watershed to judge the relevance of communication between neurons marked by the back-propagating action potential. This phenomenon is now called Spike Timing Dependent Plasticity (STDP), which many laboratories around the world have subsequently found in multiple brain regions and many theoreticians have incorporated as a learning rule. At the Max-Planck he also started exploring the micro-anatomical and physiological principles of the different neurons of the neocortex and of the mono-synaptic connections that they form - the first step towards a systematic reverse engineering of the neocortical microcircuitry to derive the blue prints of the cortical column in a manner that would allow computer model reconstruction.
He received a tenure track position at the Weizmann Institute where he continued the reverse engineering studies and also discovered a number of core principles of the structural and functional organization such as differential signaling onto different neurons, models of dynamic synapses with Misha Tsodyks, the computational functions of dynamic synapses, and how GABAergic neurons map onto interneurons and pyramidal neurons. A major contribution during this period was his discovery of Redistribution of Synaptic Efficacy (RSE), where he showed that co-activation of neurons does not only alter synaptic strength, but also the dynamics of transmission. At the Weizmann, he also found the tabula rasa principle which governs the random structural connectivity between pyramidal neurons and a non-random functional connectivity due to target selection. Markram also developed a novel computation framework with Wolfgang Maass to account for the impact of multiple time constants in neurons and synapses on information processing called liquid computing or high entropy computing.
In 2002, he was appointed Full professor at the EPFL where he founded and directed the Brain Mind Institute. During this time Markram continued his reverse engineering approaches and developed a series of new technologies to allow large-scale multi-neuron patch-clamp studies. Markrams lab discovered a novel microcircuit plasticity phenomenon where connections are formed and eliminated in a Darwinian manner as apposed to where synapses are strengthening or weakened as found for LTP. This was the first demonstration that neural circuits are constantly being re-wired and excitation can boost the rate of re-wiring.
At the EPFL he also completed the much of the reverse engineering studies on the neocortical microcircuitry, revealing deeper insight into the circuit design and built databases of the blue-print of the cortical column. In 2005 he used these databases to launched the Blue Brain Project. The BBP used IBMs most advanced supercomputers to reconstruct a detailed computer model of the neocortical column composed of 10000 neurons, more than 340 different types of neurons distributed according to a layer-based recipe of composition and interconnected with 30 million synapses (6 different types) according to synaptic mapping recipes. The Blue Brain team built dozens of applications that now allow automated reconstruction, simulation, visualization, analysis and calibration of detailed microcircuits. This Proof of Concept completed, Markrams lab has now set the agenda towards whole brain and molecular modeling.
With an in depth understanding of the neocortical microcircuit, Markram set a path to determine how the neocortex changes in Autism. He found hyper-reactivity due to hyper-connectivity in the circuitry and hyper-plasticity due to hyper-NMDA expression. Similar findings in the Amygdala together with behavioral evidence that the animal model of autism expressed hyper-fear led to the novel theory of Autism called the Intense World Syndrome proposed by Henry and Kamila Markram. The Intense World Syndrome claims that the brain of an Autist is hyper-sensitive and hyper-plastic which renders the world painfully intense and the brain overly autonomous. The theory is acquiring rapid recognition and many new studies have extended the findings to other brain regions and to other models of autism.
Markram aims to eventually build detailed computer models of brains of mammals to pioneer simulation-based research in the neuroscience which could serve to aggregate, integrate, unify and validate our knowledge of the brain and to use such a facility as a new tool to explore the emergence of intelligence and higher cognitive functions in the brain, and explore hypotheses of diseases as well as treatments.
Dario FloreanoProf. Dario Floreano is director of the Laboratory of Intelligent Systems at the Swiss Federal Institute of Technology Lausanne (EPFL). Since 2010, he is the founding director of the Swiss National Center of Competence in Robotics, a research program that brings together more than 20 labs across Switzerland. Prof. Floreano holds an M.A. in Vision, an M.S. in Neural Computation, and a PhD in Robotics. He has held research positions at Sony Computer Science Laboratory, at Caltech/JPL, and at Harvard University. His main research interests are Robotics and A.I. at the convergence of biology and engineering. Prof. Floreano made pioneering contributions to the fields of evolutionary robotics, aerial robotics, and soft robotics. He served in numerous advisory boards and committees, including the Future and Emerging Technologies division of the European Commission, the World Economic Forum Agenda Council, the International Society of Artificial Life, the International Neural Network Society, and in the editorial committee of several scientific journals. In addition, he helped spinning off two drone companies (senseFly.com and Flyability.com) and a non-for-profit portal on robotics and A.I. (RoboHub.org). Books
Manuale sulle Reti Neurali, il Mulino (in Italian), 1996 (first edition), 2006 (second edition)Evolutionary Robotics, MIT Press, 2000
Bio-Inspired Artificial Intelligence, MIT Press, 2008
Flying Insects and Robots, Springer Verlag, 2010
Wulfram GerstnerWulfram Gerstner is Director of the Laboratory of Computational Neuroscience LCN at the EPFL. His research in computational neuroscience concentrates on models of spiking neurons and spike-timing dependent plasticity, on the problem of neuronal coding in single neurons and populations, as well as on the link between biologically plausible learning rules and behavioral manifestations of learning. He teaches courses for Physicists, Computer Scientists, Mathematicians, and Life Scientists at the EPFL. After studies of Physics in Tübingen and at the Ludwig-Maximilians-University Munich (Master 1989), Wulfram Gerstner spent a year as a visiting researcher in Berkeley. He received his PhD in theoretical physics from the Technical University Munich in 1993 with a thesis on associative memory and dynamics in networks of spiking neurons. After short postdoctoral stays at Brandeis University and the Technical University of Munich, he joined the EPFL in 1996 as assistant professor. Promoted to Associate Professor with tenure in February 2001, he is since August 2006 a full professor with double appointment in the School of Computer and Communication Sciences and the School of Life Sciences. Wulfram Gerstner has been invited speaker at numerous international conferences and workshops. He has served on the editorial board of the Journal of Neuroscience, Network: Computation in Neural Systems', Journal of Computational Neuroscience', and `Science'.
Arnaud BertschTeaching & PhD PhD Students Tao Zhang, Pol Torres Vila, Nicolas Bruno Minazzo Past EPFL PhD Students as codirector Joan Teixidor, Clémentine Sophie Sarah Lipp, Nicolas Grégoire Maïno, Jiande Zhou, Jongeon Park Courses Advanced microfabrication practicals MICRO-373 This TP allows for in-depth training on advanced micro and nanofabrication methods in a clean-room environment for selected applications, gain deeper knowledge in MEMS/NEMS processes, work in a small group together with PhD stude
Pierre VandergheynstPierre Vandergheynst received the M.S. degree in physics and the Ph.D. degree in mathematical physics from the Université catholique de Louvain, Louvain-la-Neuve, Belgium, in 1995 and 1998, respectively. From 1998 to 2001, he was a Postdoctoral Researcher with the Signal Processing Laboratory, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland. He was Assistant Professor at EPFL (2002-2007), where he is now a Full Professor of Electrical Engineering and, by courtesy, of Computer and Communication Sciences. As of 2015, Prof. Vandergheynst serves as EPFL’s Vice-Provost for Education. His research focuses on harmonic analysis, sparse approximations and mathematical data processing in general with applications covering signal, image and high dimensional data processing, computer vision, machine learning, data science and graph-based data processing. He was co-Editor-in-Chief of Signal Processing (2002-2006), Associate Editor of the IEEE Transactions on Signal Processing (2007-2011), the flagship journal of the signal processing community and currently serves as Associate Editor of Computer Vision and Image Understanding and SIAM Imaging Sciences. He has been on the Technical Committee of various conferences, serves on the steering committee of the SPARS workshop and was co-General Chairman of the EUSIPCO 2008 conference. Pierre Vandergheynst is the author or co-author of more than 70 journal papers, one monograph and several book chapters. He has received two IEEE best paper awards. Professor Vandergheynst is a laureate of the Apple 2007 ARTS award and of the 2009-2010 De Boelpaepe prize of the Royal Academy of Sciences of Belgium.
Touradj EbrahimiTouradj EBRAHIMI received his M.Sc. and Ph.D., both in Electrical Engineering, from the Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland, in 1989 and 1992 respectively. In 1993, he was a research engineer at the Corporate Research Laboratories of Sony Corporation in Tokyo, where he conducted research on advanced video compression techniques for storage applications. In 1994, he served as a research consultant at AT&T Bell Laboratories working on very low bitrate video coding. He is currently Professor at EPFL heading its Multimedia Signal Processing Group. He is also the Convenor of JPEG standardization Committee. He was also adjunct Professor with the Center of Quantifiable Quality of Service at Norwegian University of Science and Technology (NTNU)from 2008 to 2012.
Prof. Ebrahimi has been the recipient of various distinctions and awards, such as the IEEE and Swiss national ASE award, the SNF-PROFILE grant for advanced researchers, Four ISO-Certificates for key contributions to MPEG-4 and JPEG 2000, and the best paper award of IEEE Trans. on Consumer Electronics . He became a Fellow of the international society for optical engineering (SPIE) in 2003. Prof. Ebrahimi has initiated more than two dozen National, European and International cooperation projects with leading companies and research institutes around the world. He is a co-founder of Genista SA, a high-tech start-up company in the field of multimedia quality metrics. In 2002, he founded Emitall SA, start-up active in the area of media security and surveillance. In 2005, he founded EMITALL Surveillance SA, a start-up active in the field of privacy and protection. He is or has been associate Editor with various IEEE, SPIE, and EURASIP journals, such as IEEE Signal Processing Magazine, IEEE Trans. on Image Processing, IEEE Trans. on Multimedia, EURASIP Image Communication Journal, EURASIP Journal of Applied Signal Processing, SPIE Optical Engineering Magazine. Prof. Ebrahimi is a member of Scientific Advisory Board of various start-up and established companies in the general field of Information Technology. He has served as Scientific Expert and Evaluator for Research Funding Agencies such as those of European Commission, The Greek Ministry of Development, The Austrian National Foundation for Scientific Research, The Portuguese Science Foundation, as well as a number of Venture Capital Companies active in the field of Information Technologies and Communication Systems. His research interests include still, moving, and 3D image processing and coding, visual information security (rights protection, watermarking, authentication, data integrity, steganography), new media, and human computer interfaces (smart vision, brain computer interface).
He is the author or the co-author of more than 200 research publications, and holds 14 patents. Prof. Ebrahimi is a member of IEEE, SPIE, ACM and IS&T.
See the URL below for more details:
http://mmspl.epfl.ch Gioele La MannoTeaching & PhD PhD Students Albert Dominguez Mantes, Xinyi Huang, Laura Lapeña Gil, Alessandro Valente, Luca Fusar Bassini, Hao-An Hsiung, Alireza Gargoorimotlagh, Morgane Alice Storey, Rosan Martine Hans, María Cristina Loureiro Casalderrey, Lada Polyakova Past EPFL PhD Students Alex Russell Lederer, Irina Khven Past EPFL PhD Students as codirector Alexandre Coudray, Alex Russell Lederer, Halima Hannah Emilie Schede, Irina Khven Courses Biological data science I: statistical learning BIOENG-210
Marion LeleuExpertise
Bioinformatics, Genomics, High-Throughput Sequencing, Data Mining
Mission
Provide advanced and personalised support and consulting in bioinformatics and biostatistics for the scientific community of EPFL, UNIL, and other Institutes.Her main areas of interest and expertise include but are not limited to, genomics, transcriptomics and epigenetics, with a strong interest in integrating multiple modalities, and choosing the appropriate statistical models, to gain a comprehensive understanding of compl
Sabine SüsstrunkProf. Dr. Sabine Süsstrunk leads the Image and Visual Representation Lab in the School of Computer and Communication Sciences (IC) at EPFL since 1999. From 2015-2020, she was also the first Director of the Digital Humanities Institute (DHI), College of Humanities (CdH). Her main research areas are in computational photography, computational imaging, color image processing and computer vision, machine learning, and computational image quality and aesthetics. Sabine has authored and co-authored over 200 publications, of which 7 have received best paper/demo awards, and holds over 10 patents. Sabine served as chair and/or committee member in many international conferences on image processing, computer vision, and image systems engineering. She is President of the Swiss Science Council SSC, Founding Member and Member of the Board (President 2014-2018) of the EPFL-WISH (Women in Science and Humanities) Foundation, Member of the Board of the SRG SSR (Swiss Radio and Television Corporation), and Member of the Board of Largo Films. She received the IS&T/SPIE 2013 Electronic Imaging Scientist of the Year Award for her contributions to color imaging, computational photography, and image quality, and the 2018 IS&T Raymond C. Bowman and the 2020 EPFL AGEPoly IC Polysphere Awards for excellence in teaching. Sabine is a Fellow of IEEE and IS&T.
Mihai Adrian IonescuAdrian M. Ionescu is Full Professor at the Swiss Federal Institute of Technology, Lausanne, Switzerland. He received the B.S./M.S. and Ph.D. degrees from the Polytechnic Institute of Bucharest, Romania and the National Polytechnic Institute of Grenoble, France, in 1989 and 1997, respectively. He has held staff and/or visiting positions at LETI-CEA, Grenoble, France and INP Grenoble, France and Stanford University, USA, in 1998 and 1999. Dr. Ionescu has published more than 600 articles in international journals and conferences. He received many Best Paper Awards in international conferences, the Annual Award of the Technical Section of the Romanian Academy of Sciences in 1994 and the Blondel Medal in 2009 for contributions to the progress in engineering sciences in the domain of electronics. He is the 2013 recipient of the IBM Faculty Award in Engineering. He served the IEDM and VLSI conference technical committees and was the Technical Program Committee (Co)Chair of ESSDERC in 2006 and 2013. He is a member of the SATW. He is director of the Laboratory of Micro/Nanoelectronic Devices (NANOLAB).
Jean-Louis ScartezziniDirector of EPFL Solar Energy and Building Physics Laboratory (1994-present); Founder & Director of ENAC Institute of Infrastructures, Resources and Environment (2002-2009); Founder & Director of EPFL Doctoral Program in Environment (2002-2009); Co-Director of EPFL Institute of Building Technology (1994-1997); Associate Professor of Building Physics at EPFL (1994-1997); Associate Professor of Building Physics at University of Geneva (1990-1997); Group Leader & Research Fellow at the EPFL Solar Energy Research Group (1981-1989); Research Fellow at the Applied Geophysics Institute of University of Lausanne (1980-1981).
Pascal FuaPascal Fua received an engineering degree from Ecole Polytechnique, Paris, in 1984 and the Ph.D. degree in Computer Science from the University of Orsay in 1989. He then worked at SRI International and INRIA Sophia-Antipolis as a Computer Scientist. He joined EPFL in 1996 where he is now a Professor in the School of Computer and Communication Science and heads the Computer Vision Laboratory. His research interests include shape modeling and motion recovery from images, analysis of microscopy images, and Augmented Reality. His research interests include shape modeling and motion recovery from images, analysis of microscopy images, and machine learning. He has (co)authored over 300 publications in refereed journals and conferences. He is an IEEE Fellow and has been an Associate Editor of IEEE journal Transactions for Pattern Analysis and Machine Intelligence. He often serves as program committee member, area chair, and program chair of major vision conferences and has cofounded three spinoff companies (Pix4D, PlayfulVision, and NeuralConcept).
Mathieu SalzmannI am a Senior Researcher at EPFL-CVLab, and, since May 2020, an Artificial Intelligence Engineer at ClearSpace (50%). Previously, I was a Senior Researcher and Research Leader in NICTA's computer vision research group. Prior to this, from Sept. 2010 to Jan 2012, I was a Research Assistant Professor at TTI-Chicago, and, from Feb. 2009 to Aug. 2010, a postdoctoral fellow at ICSI and EECS at UC Berkeley under the supervision of Prof. Trevor Darrell. I obtained my PhD in Jan. 2009 from EPFL under the supervision of Prof. Pascal Fua.
