Marion Leleu

Expertise Bioinformatics, Genomics, High-Throughput Sequencing, Data Mining Mission Provide advanced and personalised support and consulting in bioinformatics and biostatistics for the scientific community of EPFL, UNIL, and other Institutes.Her main areas of interest and expertise include but are not limited to, genomics, transcriptomics and epigenetics, with a strong interest in integrating multiple modalities, and choosing the appropriate statistical models, to gain a comprehensive understanding of complex biological questions.She has extensive experience in multi-omics analysis (scRNA-seq, scATAC-seq, Spatial-omics, SPLIT-seq, Ribo-seq), epigenetics and chromatin conformation studies ( 4C-seq, Hi-C, capture Hi-C, Drop-seq, ChIA-PET, ChIP-seq, DNAseq-seq, etc.), as well as in genomics and metagenomics analysis (WGS, Exome-seq, 16S rRNA-seq, etc.).Marion also assists with experimental design and participates to the development of specialised computational analysis pipelines. Marion has a background in Mathematics & computer science and obtained her PhD in data mining in 2004, completed jointly between academia (INSA in Lyon, France) and industry (CDC, a financial company, in Paris, France).During this time, she became interested in biological data and leveraged its repetitive structure to develop a more efficient mining algorithm for finding patterns in both financial and biological sequential data.She began her professional career as a bioinformatician and computer scientist at a Genomics Laboratory in London where she gained experience with gene expression arrays and the statistical analysis of genomics data. She then broaden her focus to epigenetics and other regulatory mechanisms by joining the Epigenetics Development and Cancer Department at the MRC in London, where she collaborated with leading researchers and worked with cutting-edge high-throughput sequencing technologies, contributing to several high-impact publications.With a wealth of experience, Marion joined the Bioinformatics & Biostatistics Core Facility at EPFL in 2009, and later moved to the BIƆC in 2020, providing advanced and personalised support and consulting to the scientific communities of EPFL, UNIL, and other institutions. Education PhD | Knowledge Discovery in Databases 2004 – 2004 INSA, Lyon, France & Caisse des d�p�ts et consignation, Paris, France Directed by Jean-Francois Boulicaut MSc in Computer Science | Information Systems, software engineering and networking 2000 – 2000 IRESTE, Nantes, France Professionals experiences Bioinformatician 2007–2009 MRC, Imperial College, LondonBioinformatician & Computer Scientist 2004–2007 Thrombosis Research Institute, London, UKResearch Engineer 2001–2004 Paris, France