Fides ZenkTeaching & PhD PhD Students Hanrong Hu, Eugenio Stefano Gentile, Ece Naz Bilgiç, Nahuel Jonas Simonet, Yong-Qi Gao, Tekin Can Sobaci, Angel Lizandro Polanco Maldonado Courses Neuroscience foundations for engineers BIOENG-310 This overview course bridges computational expertise with neuroscience fundamentals, aimed at fosteringinterdisciplinary communication and collaboration for engineering-based neuroscience programs. Practical - Zenk Lab BIO-625 You will learn to prepare
Heather Mary Elizabeth MurrayTeaching & PhD Courses Practical - Zenk Lab BIO-625 You will learn to prepare single nuclei suspensions from organoid and use them to generate chromatin accessibility (ATAC) or CUT&Tag sequencing libraries to probe the epigenetic landscape during development.You will also learn how to perform basic analysis and comparebetween samples.
Paul Joseph DysonPaul Dyson joined the Institute of Chemical Sciences and Engineering at the EPFL in 2002 where he heads the Laboratory of Organometallic and Medicinal Chemistry and between 2008 and 2016 chaired the Institute. He has won several prizes including the Werner Prize of the Swiss Chemical Society in 2004, the Award for Outstanding Achievements in Bioorganometallic Chemistry in 2010, the Centennial Luigi Sacconi Medal of the Italian Chemical Society in 2011, the Bioinorganic Chemistry Award of the Royal Society of Chemistry in 2015, the European Sustainable Chemistry Award of the European Chemical Society in 2018 and the Green Chemistry Award from the Royal Society of Chemistry in 2020. He is also a Clarivate Highly Cited Researcher and has an H-index >110 (web of science and google scholar). He was elected a Fellow of the Royal Society of Chemistry in 2010, a Fellow of the European Academy of Science in 2019 and a life-long fellow of the American Association for the Advancement of Science in 2020. Over the years he has held visiting professorships at the University of Bourgogne, University of Pierre et Marie Curie, University of Vienna, University of Rome Tor Vergara, Chimie Paristech and Shangai Jiao Tong University.Since 2016 he has been Member of the Council of the Division of Mathematics, Natural and Engineering Sciences at the Swiss National Science Foundation.Between 2016-2021 he has been Member of the Council of the Division of Mathematics, Natural and Engineering Sciences at the Swiss National Science Foundation. In 2021 he was appointed Dean of the Faculty of Basic Sciences.
Marion LeleuExpertise
Bioinformatics, Genomics, High-Throughput Sequencing, Data Mining
Mission
Provide advanced and personalised support and consulting in bioinformatics and biostatistics for the scientific community of EPFL, UNIL, and other Institutes.Her main areas of interest and expertise include but are not limited to, genomics, transcriptomics and epigenetics, with a strong interest in integrating multiple modalities, and choosing the appropriate statistical models, to gain a comprehensive understanding of compl
Maria Josefina Marcaida LopezExpertise
Protein crystallographyProtein-nucleic acid complexesKinase-small molecule interactions
FELLOWSHIPS & AWARDS • Marie Heim-Vögtlin Postdoctoral Fellowship SNSF March 2012-August 2014• CRUS Dual career couples, September 2011 & January 2012• Human Frontiers Short Term Fellowship, September- December 2009 • Juan de la Cierva Postdoctoral Fellowship 2009-2011• EMBO Long term Fellowship 2007-2008• Wellcome Trust Prize Studentship 2001-2005• Final Year Project Award, Imperial College, 2001 Education
Rudolf HoviusExpertise
•Protein structure, expression & purification•Molecular interaction & receptor activation•Fluorescence imaging & spectroscopySignalling & sensing
Mission
=> Teaching: Lecture courses, tutorials and practicals in biochemistry, biophysical chemistry of membranes and signalling processes. Participating to the Commission d'Enseignement and Commission de l'Ecole Doctorale of Chemistry and Chemical Engineering.=> Research interests: Protein function and structure, Membrane protein (especially recepto
David HackerExpertise
Animal cell cultivationTransient transfectionStable cell line generationExpression vector designProtein purification
Teaching & PhD Past EPFL PhD Students as codirector Agata Oberbek, Yashas Rajendra, Xiao Shen, Dominique Terry Monteil Jr, Sowmya Balasubramanian Courses Recombinant protein expression in animal cells for appli-cations in medicine and structural biology BIO-701 Cultivated animal cells are important hosts for the production of recombinant proteins for biochemical and
Giovanna AmbrosiniCurrent Position Senior Scientist, School of Life Sciences, Bioinformatics Competence Center, école Polythechnique Fédérale de Lausanne, Lausanne.Senior bioinformatician and software engineer with proven experience working in higher education institutions. Solid experience in scientific computing and web design. Proficient in physics and computational genomics, with a focus on high-throughput genomic sequencing data analysis (ChIP-seq, ATAC-seq, RNA-seq, scRNA-seq, and exome sequencing) and other types of
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Didier TronoAfter obtaining an M.D. from the University of Geneva and completing a clinical training in pathology, internal medicine and infectious diseases in Geneva and at Massachusetts General Hospital in Boston, Didier Trono embarked in a scientific career at the Whitehead Institute for Biomedical Research of MIT. In 1990, he joined the faculty of the Salk Institute for Biological Studies to launch a center for AIDS research. He moved back to Europe seven years later, before taking the reins of the newly created EPFL School of Life Sciences, which he directed from 2004 to 2012. He is now actively engaged in the efforts of Switzerland to integrate new technologies in the fields of precision medicine and personalized health.
Vassily HatzimanikatisDr. Vassily Hatzimanikatis is currently Associate Professor of Chemical Engineering and Bioengineering at Ecole Polytechnique Federale de Lausanne (EPFL), in Lausanne, Switzerland. Vassily received a PhD and an MS in Chemical Engineering from the California Institute of Technology, and his Diploma in Chemical Engineering from the University of Patras, in Greece. After the completion of his doctoral studies, he held a research group leader position at the Swiss Federal Institute of Technology in Zurich (ETHZ), Switzerland. Prior to joining EPFL, Vassily worked for three years in DuPont, Cargill, and Cargill Dow, and he has been assistant professor at Northwestern University, at Illinois, USA.
Vassilys research interests are in the areas of computational systems biology, biotechnology, and complexity. He is associate editor of the journals Biotechnology & Bioengineering, Metabolic Engineering and Integrative Biology, and he serves on the editorial advisory board of the journals Bioprocess and Biosystems Engineering, Journal of Chemical Technology and Biotechnology, and Industrial Biotechnology. He has written over 70 technical publications and he is co-inventor in three patents and patent applications.
Vassily is a fellow of the American Institute for Medical and Biological Engineering (2010), he was a DuPont Young Professor (2001-2004), and he has also received the Jay Bailey Young Investigator Award in Metabolic Engineering (2000), and the ACS Elmar Gaden Award (2011).
Sandra Eloise KjeldsenPositions
2008- : Laborantine (Laboratoire du Pr D. Trono), Laboratoire de virologie et génétique, EPFL, Suisse.
2004-2008: Laborantine (Laboratoire du Pr A. Trumpp), ISREC, Suisse.
2004: Assistante de recherche (Laboratoire du Pr G. Corradin), Institut de Biochimie, Université de Lausanne, Suisse.
Éducation
1999 - 2004:
Diplôme en Biologie (spécialités : Immunologie, Biochimie et Pharmacologie)
Université de Lausanne, Suisse.
Juin 1999:
Baccalauréat Scientifique, France. Christian IseliTeaching & PhD Courses Bioinformatic Analysis of RNA-sequencing (Fall) BIO-693(a) Bioinformatic Analysis of RNA-sequencing (Spring) BIO-693(b) This course will take place at EPFL in June 2026, from 8th to 12th, in room AAC 137.It introduces the workflows and techniques that are used for the analysis of bulk and single-cell RNA-seq data. It empowers students to understand and analyze their own data. Methods: omics in biomedical research BIOENG-519 High-throughp
