Rudolf HoviusExpertise
•Protein structure, expression & purification•Molecular interaction & receptor activation•Fluorescence imaging & spectroscopySignalling & sensing
Mission
=> Teaching: Lecture courses, tutorials and practicals in biochemistry, biophysical chemistry of membranes and signalling processes. Participating to the Commission d'Enseignement and Commission de l'Ecole Doctorale of Chemistry and Chemical Engineering.=> Research interests: Protein function and structure, Membrane protein (especially recepto
Henning Paul-Julius StahlbergMission
We use high-resolution cryo-electron microscopy to study neurodegeneration and other protein systems. We also develop novel imaging technology in the areas of electron microscopy hardware and applications, sample preparation, data collection schemes, and data analysis software systems. The Stahlberg group is supported by the University of Lausanne, Faculty of Medicine and Biology, and by the EPFL, Faculty of Basic Sciences, Physics Institute. The LBEM is a research laboratory of both UNIL and EPFL.
Horst PickTeaching & PhD PhD Students Vivek Prakash, Yang Wang Past EPFL PhD Students as codirector Olivia Baud, Thamani Dahoun, Enio Daniel Zanchetta Courses Biotechnology lab (for CGC) ChE-433 This laboratory-training course is designed to give students a comprehensive insight into laboratory research techniques in the field of biotechnology and pharmaceutical biotechnology with practices employed in the industry. Accompanying lectures provide the theoretical background. Chemosensory receptors:
Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Vladislav SlamaExpertise
Atomistic modeling of the biological pigment protein complexes consisting of molecular dynamics simulations (AMBER), computing ground and excited state properties of molecules and molecular aggregates including the effects of the environment (Gaussian, PyScf) and simulating excitation dynamics and optical spectra using quantum master equation approaches (Quantarhei).
Expertise
Atomistic modeling of the biological pigment protein complexes consisting of molecular dynamics simulations (AMBER), compu
Kumar Varoon AgrawalExpertise
Prof. Kumar Varoon Agrawal leads research at EPFL on advanced membrane materials and processes for energy-efficient molecular separations. His work focuses on atomically thin porous graphene film, and two-dimensional zeolite & metal–organic framework membranes that enable selective transport of gases and ions, with applications in carbon capture, hydrogen purification, ammonia separation, and resource recovery. By combining materials chemistry, nanofluidics, transport phenomena, atomistic simulati
Anne-Florence Raphaëlle BitbolI was trained in physics, and always had a strong interest in biology. I am broadly interested in understanding biological phenomena in a quantitative way, through physical concepts and mathematical and computational tools. I investigate the relative impacts of optimization and historical contingency in biological evolution, both at the scale of protein sequences and at the scale of microbial populations.Here is my research group website.Curriculum vitae Here is my complete CV. Professional experience:Since
Florence PojerExpertise
MER and Head of Unit - Protein Production and Structure Reseach Core Facility within the Life Sciences School - PTPSP: Expertise in Integrative protein Structural Biology (mainly X-ray Crystallography and Cryo-EM) and production of macromolecules in mammalian and bacterial cells. Innovate4Life team member at SV: i4L supports the next generation of entrepreneurs through education, mentorship, and funding, to translate life sciences discoveries into technologies that benefit society. Education and
Arnaud BertschTeaching & PhD PhD Students Tao Zhang, Pol Torres Vila, Nicolas Bruno Minazzo Past EPFL PhD Students as codirector Joan Teixidor, Clémentine Sophie Sarah Lipp, Nicolas Grégoire Maïno, Jiande Zhou, Jongeon Park Courses Advanced microfabrication practicals MICRO-373 This TP allows for in-depth training on advanced micro and nanofabrication methods in a clean-room environment for selected applications, gain deeper knowledge in MEMS/NEMS processes, work in a small group together with PhD stude
Michaël UnserExpertise
Image Processing, Medical Imaging, Biological Imaging, Wavelets, Splines, Multiresolution
Michael Unser is Full Professor with EPFL’s school of Engineering and the academic director of EPFL's Center for Imaging, Lausanne, Switzerland. His primary areas of investigation are signal processing, biomedical imaging and applied functional analysis. He is internationally recognized for his research contributions to sampling theory, wavelets, the use of splines for image processing, stochastic processes,
Daniel SageExpertise
PublicationsPublications
Coordinates Biomedical Imaging GroupAddressEPFL STI-IMT-LIB, BM 4.135, Station 17, CH-1015 Lausanne, SwitzerlandTel.+41 21 693 51 89Fax.+41 21 693 68 10Emaildaniel.sage@epfl.chWeb pagehttp://bigwww.epfl.ch/sage/OfficeBM 4.135
Teaching & PhD Past EPFL PhD Students as codirector Daniel Andreas Schmitter, Anaïs Badoual, Laurène Donati Courses Bioimage informatics BIO-410 The course provides a comprehensive overview of methods, algorithms, and computer tools us Coralie BussoExpériences professionnelles Apprentie Laborantine 2001–2004 CMU Dpt. de physiologie cellulaire et métabolisme
RechercheCentrosomes promote timely mitotic entry in C. ele Dev Cell. 2007 Apr;12(4):531-41.Centrosomes promote timely mitotic entry in C. elegans embryos.Hachet V, Canard C, Gönczy P.SourceSwiss Institute for Experimental Cancer Research (ISREC), and School of Life Sciences, Swiss Federal Institute of Technology (EPFL), CH-1066 Lausanne, Switzerland.AbstractSeveral mitotic regulators, including
Christoph BostedtTeaching & PhD PhD Students Eloisa Florence Manetti, Wenyi Jiang, Hankai Zhang, Loïc Lucien Cédric Bassement, Silas Strebel, Eliot Jermann Past EPFL PhD Students Jonas Knurr, Ningchen Yang Courses Optical methods in chemistry CH-417 Introduction and application of photon based tools for chemical sciences: from basic concepts to optical and x-ray lasers Physical Chemistry Seminar 1: Trends CH-643 Students can learn about the broader research in Phyiscal Chemistry and broaden
Patrick Daniel BarthProfessor Patrick Barth is Associate Professor at EPFL and Adjunct Associate Professor at Baylor College of Medicine, Houston, TX, USA. He received training in Physics, Chemistry and Biology (University of Paris, ENS) in France and performed his PhD at the Commissiariat a l'Energie Atomique in Saclay, France on structure/function studies of membrane proteins (photosystem I) using biochemical and biophysical experimental techniques. He carried out postdoctoral studies at University of California at Berkeley with Tom Alber on computational development for calculating protein electrostatics and designing de novo selective peptide inhibitors of cellular protein interactions. He then went to the University of Washington as a postdoctoral fellow and instructor in David Baker's laboratory to develop computational techniques in the software Rosetta for predicting and designing membrane protein structures. He started his independent career and received tenure at Baylor College of Medicine. He will continue at EPFL to marry computation and experiment for understanding the molecular determinants of signal transduction, as well as modeling and designing membrane proteins with novel functions for various synthetic biology and therapeutic applications.
Graham KnottGraham Knott received his degree in physiology from the University of Southampton, UK, in 1990, and his PhD in neuroscience from the University of Tasmania, Australia, in 1995. He moved to the University of Lausanne in Switzerland in 1999 where he researched the plasticity of neuronal connectivity in the adult brain, developing correlative light and electron microscopy methods for the analysis of in vivo imaged neurons. In 2006 Graham joined the Ecole Polytechnique Fédérale de Lausanne, establishing the Bio Electron Microscopy Facility and has continued his research interests in brain plasticity and 3D electron microscopy.
Yves PerriardYves Perriard was born in Lausanne in 1965. He received the M. Sc. in Microengineering from the Swiss Federal Institute of Technology - Lausanne (EPFL) in 1989 and the Ph D. degree in 1992. Co-founder of Micro-Beam SA, he was CEO of this company involved in high precision electric drive. Senior lecturer from 1998 and professor since 2003, he is currently director of Laboratory of Integrated Actuators. His research interests are in the field of new actuator design and associated electronic devices. In 2009, he is appointed Vice-Director of the Microengineering Institute in Neuchâtel until 2011. In 2013 the Federal Council has named him the the CTI commission in Bern. In 2014 he is appointed guest professor at Zhejiang University in China. In 2017, the lab is granted by the Werner Siemens Foundation of an amount of 12 millions CHF in order to set up a new Center for Artificial Muscules. Since 2018, he is Expert with Innosuisse, the new Swiss Innovation Agency. http://scholar.google.com/citations?hl=fr&user=V2onuO8AAAAJ https://actu.epfl.ch/news/a-12-million-franc-donation-to-create-a-center-for/ Anna Fontcuberta i Morral2014 Associate Professor at the Institut des Matériaux, EPFL
2008 Assistant Professor Tenure Track at the Institut des Matériaux, EPFL
2009 Habilitation in Physics, Technische Universität München
2005-2010 Marie Curie Excellence Grant Team Leader at Walter Schottky Institut, Technische Universität München, on leave from Centre National de la Recherche Scientifique (CNRS, France)
2004-2005 Visiting Scientist at the California Institute of Technology, on leave from CNRS; Senior Scientist and co-founder of Aonex Technologies (a startup company for large area layer transfer of InP and Ge on foreign substrates for the main application of multi-junction solar cells)
2003 Permanent Research Fellow at CNRS, Ecole Polytechnique, France
2001-2002 Postdoctoral Scholar at the California Institute of Technology
Study of wafer bonding and hydrogen-induced exfoliation processes for integration of mismatched materials in views of photovoltaic applications
Sponsor: Professor Harry A. Atwater
1998-2001 PhD in Materials Science, Ecole Polytechnique
Study of polymorphous silicon: growth mechanisms, optical and structural properties. Application to Solar Cells and Thin Film Transistors
Advisor: Pere Roca i Cabarrocas
1997-1998 Diplôme dEtudes Approfondis (D.E.A.) in Materials Science at Université Paris XI, France .
1993-1997 BA in Physics at Universitat de Barcelona
