Polymer Coiled-Coil Conjugates: Potential for Development as a New Class of Therapeutic “Molecular Switch”

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We prove the non-planarity of a family of 3-regular graphs constructed from the solutions to the Markoff equation x2 + y2 + z2 = xyz modulo prime numbers greater than 7. The proof uses Euler characteristic and an enumeration of the short cycles in these gr ...

Our ability to study and valorize the lignin fraction of biomass is hampered by the fundamental and still unmet challenge of precisely quantifying native lignin's structural features. Here, we developed a rapid elevated-temperature H-1-C-13 Heteronuclear S ...

Motivated by the transfer of proofs between proof systems, and in particular from first order automated theorem provers (ATPs) to interactive theorem provers (ITPs), we specify an extension of the TPTP derivation text format to describe proofs in first-ord ...

We study the proof theory and algorithms for orthologic, a logical system based on ortholattices, which have shown practical relevance in simplification and normalization of verification conditions. Ortholattices weaken Boolean algebras while having polyno ...

A hash proof system (HPS) is a form of implicit proof of membership to a language. Out of the very few existing post-quantum HPS, most are based on languages of ciphertexts of code-based or lattice-based cryptosystems and inherently suffer from a gap cause ...

We present LISA, a proof system and proof assistant for constructing proofs in schematic first-order logic and axiomatic set theory. The logical kernel of the system is a proof checker for first-order logic with equality and schematic predicate and fun ...

Recent advancements in miniature devices with higher computational capabilities and ultralow power consumption have accelerated the development of wearable sensors, actuators, and energy harvesters everywhere. The ultimate aim of such a technological revol ...

BackgroundIt is generally accepted that most evolutionary transformations at the phenotype level are associated either with rearrangements of genomic regulatory elements, which control the activity of gene networks, or with changes in the amino acid conten ...

Advances in mobile computing have paved the way for new types of distributed applications that can be executed solely by mobile devices on Device-to-Device (D2D) ecosystems (e.g., crowdsensing). Sophisticated applications, like cryptocurrencies, need distr ...

Synthetic biology aims to engineer cells as miniature biological devices to sense, process, and respond to exogenous stimuli. Protein switches are designed to sense and respond to various molecular queues in a fast and specific manner, which fits the requi ...

The training of neural networks by gradient descent methods is a cornerstone of the deep learning revolution. Yet, despite some recent progress, a complete theory explaining its success is still missing. This article presents, for orthogonal input vectors, ...

Gene therapy offers the possibility to treat or even cure diseases originating from genetic defects by introducing a therapeutic gene in target cells or correcting the initial defective gene. Amongst different options, non-viral vectors rely on the deliver ...

Polymers when self-cross-linked into single-chain nanoparticles bear some resemblance to folded proteins; yet proteins have clear energy landscapes that determine precisely folded structures, while single-chain polymer nanoparticles (SCNPs) have more undef ...

We provide a counterexample to the performance guarantee obtained in the paper "Il'ev, V., Linker, N., 2006. Performance guarantees of a greedy algorithm for minimizing a supermodular set function on comatroid", which was published in Volume 171 of the Eur ...

Transient bioelectronics has grown fast, opening possibilities never thought before. In medicine, transient implantable devices are interesting because they could eliminate the risks related to surgical retrieval and reduce the chronic foreign body reactio ...

The controllability cost for the heat equation as the control time

T

goes to 0 is well-known of the order

e^{C/T}

for some positive constant

C

, depending on the controlled domain and for all initial datum. In this paper, we prove that the constant $C ...

The mechanism of photoinduced symmetry-breaking charge separation in solid cyanine salts at the base of organic photovoltaic and optoelectronic devices is still debated. Here, we employ femtosecond transient absorption spectroscopy (TAS) to monitor the cha ...

In this paper we study the moments of polynomials from the Askey scheme, and we focus on Askey-Wilson polynomials. More precisely, we give a combinatorial proof for the case where d = 0. Their values have already been computed by Kim and Stanton in 2015, h ...

Polymer brushes are a specific class of polymer thin films in which each chain is tethered to the underlying substrate via one chain end. In sufficiently densely grafted assemblies, the individual polymer chains are forced into an extended chain conformati ...

A promising approach to influence and control the photophysical properties of conjugated polymers is directing their molecular conformation by templating. We explore here the templating effect of single-stranded DNA oligomers (ssDNAs) on cationic polythiop ...

Polymer Coiled-Coil Conjugates: Potential for Development as a New Class of Therapeutic “Molecular Switch”

Chattez avec Graph Search

Non-planarity of Markoff graphs mod p

Quantification of Native Lignin Structural Features with Gel-Phase 2D-HSQC0 Reveals Lignin Structural Changes During Extraction

SC-TPTP: An Extension of the TPTP Derivation Format for Sequent-Based Calculus

Orthologic with Axioms

A Gapless Post-quantum Hash Proof System in the Hamming Metric

LISA – A Modern Proof System

Tailor-made Piezoelectric Elastomer Materials

Wide-scale identification of novel/eliminated genes responsible for evolutionary transformations

Toward Mobile Distributed Ledgers

Rational design of protein switches: applications in synthetic biology and cancer immunotherapy

Gradient flow dynamics of shallow ReLU networks for square loss and orthogonal inputs

Engineering of chitosan-based derivatives for non-viral gene delivery

Control and Characterization of the Compactness of Single-Chain Nanoparticles

A comment on performance guarantees of a greedy algorithm for minimizing a supermodular set function on comatroid

All-polymeric transient neural probe for prolonged in-vivo electrophysiological recordings

A dependence of the cost of fast controls for the heat equation on the support of initial datum

Critical role of H-aggregation for high-efficiency photoinduced charge generation in pristine pentamethine cyanine salts

Computation of Al-Salam Carlitz and Askey-Wilson moments using Motzkin paths

Mechanical Activation of Chemical Bonds at Polymer Interfaces

Structural and Photophysical Templating of Conjugated Polyelectrolytes with Single-Stranded DNA