Wearable exoskeletons to support ambulation in people with neuromuscular diseases, design rules and control

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Publications associées (32)

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Gait Variability to Phenotype Common Orthopedic Gait Impairments Using Wearable Sensors

Wei Zhang

Mobility impairments are a common symptom of age-related degenerative diseases. Gait features can discriminate those with mobility disorders from healthy individuals, yet phenotyping specific pathologies remains challenging. This study aims to identify if ...

MDPI2022

Knee adduction moment decomposition: Toward better clinical decision-making

Kamiar Aminian, Xavier Crevoisier, Robin Martin, Mina Arabbaniasad

Knee adduction moment (KAM) is correlated with the progression of medial knee osteoarthritis (OA). Although a generic gait modification can reduce the KAM in some patients, it may have a reverse effect on other patients. We proposed the "decomposed ground ...

FRONTIERS MEDIA SA2022

Assessment of idiopathic inflammatory myopathy using a deep learning method for muscle T2 mapping segmentation

Qian Wang, Tobias Kober, Tom Hilbert

Objective To investigate the utility of an automatic deep learning (DL) method for segmentation of T2 maps in patients with idiopathic inflammatory myopathy (IIM) against healthy controls, and also the association of quantitative T2 values in patients with ...

SPRINGER2022

State-of-the-art of data collection, analytics, and future needs of transmission utilities worldwide to account for the continuous growth of sensing data

Mario Paolone

Nowadays, transmission system operators require higher degree of observability in real-time to gain situational awareness and improve the decision-making process to guarantee a safe and reliable operation. Digitalization of energy systems allows utilities ...

ELSEVIER SCI LTD2022

Dataset for the validation of a Computational Thinking test for upper primary school (grades 3-4)

Francesco Mondada, Barbara Bruno, Jessica Elke Dehler Zufferey, Laila Abdelsalam El-Hamamsy

This dataset contains quantitative student data acquired during the administration of a new computational thinking assessment for upper primary school (grades 3 and 4). Over 1500 students (approximately half in grade 3 and half in grade 4) participated in ...

2022

Graph Embedding for Retrieval

Chi Thang Duong

Information retrieval (IR) systems such as search engines are important for people to find what they need among the tremendous amount of data available in their organization or on the Internet. These IR systems enable users to search in a large data collec ...

EPFL2022

Astrocyte-targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast-fatigable motor units in a mouse model of amyotrophic lateral sclerosis

Patrick Aebischer, Bernard Schneider, Cylia Cloé Rochat, Nathalie Marie Géraldine Bernard

In amyotrophic lateral sclerosis (ALS) caused by SOD1 gene mutations, both cell-autonomous and noncell-autonomous mechanisms lead to the selective degeneration of motoneurons (MN). Here, we evaluate the therapeutic potential of gene therapy targeting mutat ...

WILEY2022

Sensor-based control strategies for integration of epidural electrical stimulation in rehabilitation after spinal cord injury

Miroslav Caban

Spinal Cord Injury (SCI) results in damage to neural circuitry connecting the brain to the periphery. Consequently, sensory and motor function is lost, to varying degree, depending on the site and severity of the lesion. More than half of spinal cord injur ...

EPFL2022

Extracting transport channel transmissions in scanning tunneling microscopy using superconducting excess current

Klaus Kern, Jacob Senkpiel

Transport through quantum coherent conductors, such as atomic junctions, is described by conduction channels. Information about the number of channels and their transmissions can be extracted from various sources, such as multiple Andreev reflections, dyna ...

AMER PHYSICAL SOC2022

Evaluation of anterior cruciate ligament surgical reconstruction through finite element analysis

Dimitar Yuriev Stanev

Anterior cruciate ligament (ACL) tear is one of the most common knee injuries. The ACL reconstruction surgery aims to restore healthy knee function by replacing the injured ligament with a graft. Proper selection of the optimal surgery parameters is a comp ...

Nature Portfolio2022

Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy

Johan Auwerx, Hao Li, Davide D'Amico, Pénélope Andreux, Tanes Imamura de Lima, Pirkka-Pekka Untamo Laurila, Martin Rainer Wohlwend, Peiling Luan

Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy, and despite advances in genetic and pharmacological disease-modifying treatments, its management remains a major challenge. Mitochondrial dysfunction contributes to DMD, yet the mecha ...

AMER ASSOC ADVANCEMENT SCIENCE2021

Gangliosides: Treatment Avenues in Neurodegenerative Disease

Pierre Magistretti

Gangliosides are cell membrane components, most abundantly in the central nervous system (CNS) where they exert among others neuro-protective and -restorative functions. Clinical development of ganglioside replacement therapy for several neurodegenerative ...

FRONTIERS MEDIA SA2019