Optical imaging of molecules and their dynamics from surfaces to nanoscale confinement

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Optical manipulation and detection of biological particulates are crucial procedures in biophotonics. Optical sectioning (OS) opens the avenue to three-dimensional (3D) microscopy, but nonoptical approaches, including sample adhesion and mechanical scannin ...

Neurodegenerative diseases, such as Alzheimer's, Parkinson's, and Huntington's, afflict tens of millions of patients worldwide. They are characterized by protein aggregation and progressive neuronal loss, leading to cognitive and motor impairments, and ult ...

Latest advances in super-resolution microscopy allow the study of subcellular features at the level of single proteins, which could lead to discoveries in fundamental biological processes, specifically in cell signaling mediated by membrane receptors. Desp ...

Centrioles are evolutionarily conserved microtubule-based organelles essential for cell division, ciliogenesis, and cell polarity. While centrioles are critical for many cellular processes, their selective elimination is crucial during specific development ...

With the advancement of high harmonic generation and X-ray free-electron lasers (XFELs) to the attosecond domain, the studies of the ultrafast electron and spin dynamics became possible. Yet, the methods for efficient control and measurement of the quantum ...

Spin wave nonreciprocity is crucial for signal processing in magnonic circuits. Domain walls (DWs) have been suggested as channels for nonreciprocal spin waves (magnons) with directional‐dependent properties. However, the experimental investigations are ch ...

Epsilon-near-zero (ENZ) materials, i.e., materials with a vanishing real part of the permittivity, have become an increasingly desirable platform for exploring linear and nonlinear optical phenomena in nanophotonic and on-chip environments. ENZ materials i ...

The specific and covalent labeling of the protein HaloTag with fluorescent probes in living cells makes it a powerful tool for bioimaging. However, the irreversible attachment of the probe to HaloTag precludes imaging applications that require transient bi ...

Compound structural identification for non-targeted screening of organic molecules in complex mixtures is commonly carried out using liquid chromatography coupled to tandem mass spectrometry (UHPLC-HRMS/MS and related techniques). Instrumental developments ...

To date, the feasibility of super-resolution microscopy for imaging live and thick samples is still limited. Stimulated emission depletion (STED) microscopy requires high-intensity illumination to achieve sub-diffraction resolution, potentially introducing ...

We present an analog silicon photomultiplier (SiPM) based on a standard 55-nm Bipolar-CMOS-DMOS (BCD) technology. The SiPM is composed of 16 x 16 single-photon avalanche diodes (SPADs) and measures 0.29 x 0.32 mm(2). Each SPAD cell is passively quenched by ...

Optical imaging of molecules and their dynamics from surfaces to nanoscale confinement

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Optical tweeze-sectioning microscopy for 3D imaging and manipulation of suspended cells

Intelligent and Self-Driving Microscopy of Protein Aggregation in Neurodegenerative Diseases

Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution

Dissecting the mechanisms of centriole stability in Caenorhabditis elegans: Focus on SAS-1

Non-Resonant Magnetic X-ray Scattering as a Probe of Ultrafast Molecular Spin-State Dynamics: An Ab Initio Theory

Nonreciprocal Spin Waves in Nanoscale Hybrid Néel–Bloch–Néel Domain Walls Detected by Scanning X‐Ray Microscopy in Perpendicular Magnetic Anisotropic Fe/Gd Multilayers

Individual nanostructures in an epsilon-near-zero material probed with 3D-sculpted light

Exchangeable HaloTag Ligands for Super-Resolution Fluorescence Microscopy

Harnessing data science to improve molecular structure elucidation from tandem mass spectrometry

Focus image scanning microscopy for sharp and gentle super-resolved microscopy

On Analog Silicon Photomultipliers in Standard 55-nm BCD Technology for LiDAR Applications